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Neural circuits are able to perform computations under very diverse conditions and requirements. The required computations impose clear constraints on their fine-tuning: a rapid and maximally informative response to stimuli in general…

Neurons and Cognition · Quantitative Biology 2019-10-22 Jens Wilting , Jonas Dehning , Joao Pinheiro Neto , Lucas Rudelt , Michael Wibral , Johannes Zierenberg , Viola Priesemann

Inhibition is considered to shape neural activity, and broaden its pattern repertoire. In the sensory organs, where the anatomy of neural circuits is highly structured, lateral inhibition sharpens contrast among stimulus properties. The…

Neurons and Cognition · Quantitative Biology 2018-09-18 Netta Haroush , Shimon Marom

Recurrent neural networks with balanced excitation and inhibition exhibit irregular asynchronous dynamics, which is fundamental for cortical computations. Classical balance mechanisms require strong external inputs to sustain finite firing…

Neurons and Cognition · Quantitative Biology 2025-10-21 David Angulo-Garcia , Alessandro Torcini

Neurons in the central nervous system are affected by complex and noisy signals due to fluctuations in their cellular environment and in the inputs they receive from many other cells 1,2. Such noise usually increases the probability that a…

Neurons and Cognition · Quantitative Biology 2008-05-06 Boris S. Gutkin , Juergen Jost , Henry C. Tuckwell

We study a network of spiking neurons with heterogeneous excitabilities connected via inhibitory delayed pulses. For globally coupled systems the increase of the inhibitory coupling reduces the number of firing neurons by following a Winner…

Disordered Systems and Neural Networks · Physics 2019-05-29 Stefano Luccioli , David Angulo Garcia , Alessandro Torcini

We study analytically the dynamics of a network of sparsely connected inhibitory integrate-and-fire neurons in a regime where individual neurons emit spikes irregularly and at a low rate. In the limit when the number of neurons N tends to…

Disordered Systems and Neural Networks · Physics 2007-05-23 N. Brunel , V. Hakim

Collective oscillations and their suppression by external stimulation are analyzed in a large-scale neural network consisting of two interacting populations of excitatory and inhibitory quadratic integrate-and-fire neurons. In the limit of…

Neurons and Cognition · Quantitative Biology 2021-07-14 Kestutis Pyragas , Augustinas P. Fedaravičius , Tatjana Pyragienė

The theory of `Balanced Neural Networks' is a very popular explanation for the high degree of variability and stochasticity in the brain's activity. We determine equations for the hydrodynamic limit of a balanced all-to-all network of 2n…

Mathematical Physics · Physics 2024-12-24 James MacLaurin , Pedro Vilanova

Experimental manipulations perturb the neuronal activity. This phenomenon is manifested in the fMRI response. Dynamic causal model and its variants can model these neuronal responses along with the BOLD responses [1, 2, 3, 4, 5] .…

Neurons and Cognition · Quantitative Biology 2021-01-15 Sayan Nag

The "edge of chaos" phase transition in artificial neural networks is of renewed interest in light of recent evidence for criticality in brain dynamics. Statistical mechanics traditionally studied this transition with connectivity $k$ as…

Disordered Systems and Neural Networks · Physics 2019-07-17 Lorenz Baumgarten , Stefan Bornholdt

Many mathematical models of interacting agents assume that individual interactions scale down in proportion to the network size, ensuring that the combined input received from the network does not diverge. In theoretical neuroscience,…

Analysis of PDEs · Mathematics 2025-11-10 Cristobal Quininao , Jonathan Touboul

The dynamical properties of a diluted fully-inhibitory network of pulse-coupled neurons are investigated. Depending on the coupling strength, two different phases can be observed. At low coupling the evolution rapidly converges towards…

Disordered Systems and Neural Networks · Physics 2009-11-11 Ruediger Zillmer , Roberto Livi , Antonio Politi , Alessandro Torcini

We revisit the dynamics of a prototypical model of balanced activity in networks of spiking neutrons. A detailed investigation of the thermodynamic limit for fixed density of connections (massive coupling) shows that, when inhibition…

Adaptation and Self-Organizing Systems · Physics 2018-09-03 Ekkehard Ullner , Antonio Politi , Alessandro Torcini

In view of ever-changing conditions both in the external world and in intrinsic brain states, maintaining the robustness of computations poses a challenge, adequate solutions to which we are only beginning to understand. At the level of…

Neurons and Cognition · Quantitative Biology 2022-03-29 Nelson Niemeyer , Jan-Hendrik Schleimer , Susanne Schreiber

We introduce and solve a general model of dynamic response under external perturbations. This model captures a wide range of systems out of equilibrium including Ising models of physical systems, social opinions, and population genetics.…

Exactly Solvable and Integrable Systems · Physics 2007-11-19 David D. Chinellato , Marcus A. M. de Aguiar , Irving R. Epstein , Dan Braha , Yaneer Bar-Yam

Commonly studied cellular automata are memoryless and have fixed topology of connections between cells. However by allowing updates of links and short-term memory in cells we may potentially discover novel complex regimes of spatio-temporal…

Cellular Automata and Lattice Gases · Physics 2012-12-13 Ramon Alonso-Sanz , Andrew Adamatzky

Synaptic connections between neurons in the brain are dynamic because of continuously ongoing spine dynamics, axonal sprouting, and other processes. In fact, it was recently shown that the spontaneous synapse-autonomous component of spine…

Neurons and Cognition · Quantitative Biology 2018-01-08 David Kappel , Robert Legenstein , Stefan Habenschuss , Michael Hsieh , Wolfgang Maass

Biological cortical networks are potentially fully recurrent networks without any distinct output layer, where recognition may instead rely on the distribution of activity across its neurons. Because such biological networks can have rich…

Neurons and Cognition · Quantitative Biology 2022-11-14 Pakorn Uttayopas , Xiaoxiao Cheng , Udaya Bhaskar Rongala , Henrik Jörntell , Etienne Burdet

At functional scales, cortical behavior results from the complex interplay of a large number of excitable cells operating in noisy environments. Such systems resist to mathematical analysis, and computational neurosciences have largely…

Neurons and Cognition · Quantitative Biology 2014-03-05 Mathieu Galtier , Jonathan Touboul

Balanced neural networks -- in which excitatory and inhibitory inputs compensate each other on average -- give rise to a dynamical phase dominated by fluctuations called asynchronous state, crucial for brain functioning. However, structural…

Statistical Mechanics · Physics 2024-03-05 Jorge Pretel , Victor Buendía , Joaquín J. Torres , Miguel A. Muñoz