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This study proposes an efficient neural network with convolutional layers to classify significantly class-imbalanced clinical data. The data are curated from the National Health and Nutritional Examination Survey (NHANES) with the goal of…

Quantitative Methods · Quantitative Biology 2020-04-24 Aniruddha Dutta , Tamal Batabyal , Meheli Basu , Scott T. Acton

Imbalanced Data (ID) is a problem that deters Machine Learning (ML) models for achieving satisfactory results. ID is the occurrence of a situation where the quantity of the samples belonging to one class outnumbers that of the other by a…

Small, imbalanced datasets and poor input image quality can lead to high false predictions rates with deep learning models. This paper introduces Class-Based Image Composition, an approach that allows us to reformulate training inputs…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Hlali Azzeddine , Majid Ben Yakhlef , Soulaiman El Hazzat

Cryo-electron tomography (cryo-ET) is an imaging technique that allows three-dimensional visualization of macro-molecular assemblies under near-native conditions. Cryo-ET comes with a number of challenges, mainly low signal-to-noise and…

One challenging property lurking in medical datasets is the imbalanced data distribution, where the frequency of the samples between the different classes is not balanced. Training a model on an imbalanced dataset can introduce unique…

Image and Video Processing · Electrical Eng. & Systems 2022-04-06 Ashkan Khakzar , Yawei Li , Yang Zhang , Mirac Sanisoglu , Seong Tae Kim , Mina Rezaei , Bernd Bischl , Nassir Navab

Deep learning plays an important role in modern agriculture, especially in plant pathology using leaf images where convolutional neural networks (CNN) are attracting a lot of attention. While numerous reviews have explored the applications…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Jianping Yao , Son N. Tran , Saurabh Garg , Samantha Sawyer

Learning from imbalanced data is a challenging task. Standard classification algorithms tend to perform poorly when trained on imbalanced data. Some special strategies need to be adopted, either by modifying the data distribution or by…

Machine Learning · Computer Science 2022-08-26 Asif Newaz , Shahriar Hassan , Farhan Shahriyar Haq

Clinicians usually combine information from multiple sources to achieve the most accurate diagnosis, and this has sparked increasing interest in leveraging multimodal deep learning for diagnosis. However, in real clinical scenarios, due to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Kai Han , Chongwen Lyu , Lele Ma , Chengxuan Qian , Siqi Ma , Zheng Pang , Jun Chen , Zhe Liu

Class imbalance is a challenging issue in practical classification problems for deep learning models as well as traditional models. Traditionally successful countermeasures such as synthetic over-sampling have had limited success with…

Machine Learning · Computer Science 2017-07-14 Shin Ando , Chun-Yuan Huang

Morphologies of red blood cells are normally interpreted by a pathologist. It is time-consuming and laborious. Furthermore, a misclassified red blood cell morphology will lead to false disease diagnosis and improper treatment. Thus, a…

Image and Video Processing · Electrical Eng. & Systems 2025-02-06 Kitsuchart Pasupa , Supawit Vatathanavaro , Suchat Tungjitnob

Intelligent diagnosis method based on data-driven and deep learning is an attractive and meaningful field in recent years. However, in practical application scenarios, the imbalance of time-series fault is an urgent problem to be solved.…

Machine Learning · Computer Science 2021-07-15 Xingtai Gui , Jiyang Zhang

Deep convolutional neural network (DCNN) models have been widely explored for skin disease diagnosis and some of them have achieved the diagnostic outcomes comparable or even superior to those of dermatologists. However, broad…

Computer Vision and Pattern Recognition · Computer Science 2022-02-14 Peng Yao , Shuwei Shen , Mengjuan Xu , Peng Liu , Fan Zhang , Jinyu Xing , Pengfei Shao , Benjamin Kaffenberger , Ronald X. Xu

The application of data mining, machine learning and artificial intelligence techniques in the field of diagnostics is not a new concept, and these techniques have been very successfully applied in a variety of applications, especially in…

Machine Learning · Computer Science 2020-08-07 Ayush Khaneja , Siddharth Srivastava , Astha Rai , A S Cheema , P K Srivastava

Many natural language processing (NLP) tasks are naturally imbalanced, as some target categories occur much more frequently than others in the real world. In such scenarios, current NLP models still tend to perform poorly on less frequent…

Computation and Language · Computer Science 2023-02-23 Sophie Henning , William Beluch , Alexander Fraser , Annemarie Friedrich

Cryogenic electron microscopy (Cryo-EM) has become an essential tool for capturing high-resolution biological structures. Despite its advantage in visualizations, the large storage size of Cryo-EM data file poses significant challenges for…

Machine Learning · Computer Science 2025-12-16 Chunyu Zou

Cellular Electron Cryotomography (CryoET) offers the ability to look inside cells and observe macromolecules frozen in action. A primary challenge for this technique is identifying and extracting the molecular components within the crowded…

Quantitative Methods · Quantitative Biology 2021-08-04 Muyuan Chen , Wei Dai , Ying Sun , Darius Jonasch , Cynthia Y He , Michael F. Schmid , Wah Chiu , Steven J Ludtke

Segmentation and classification of cell nuclei in histopathology images using deep neural networks (DNNs) can save pathologists' time for diagnosing various diseases, including cancers, by automating cell counting and morphometric…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Amruta Parulekar , Utkarsh Kanwat , Ravi Kant Gupta , Medha Chippa , Thomas Jacob , Tripti Bameta , Swapnil Rane , Amit Sethi

Class imbalance is a problem of significant importance in applied deep learning where trained models are exploited for decision support and automated decisions in critical areas such as health and medicine, transportation, and finance. The…

Machine Learning · Computer Science 2020-12-07 Colin Bellinger , Roberto Corizzo , Nathalie Japkowicz

Cryo-electron tomography (cryo-ET) provides direct 3D visualization of macromolecules inside the cell, enabling analysis of their in situ morphology. This morphology can be regarded as an SE(3)-invariant, denoised volumetric representation…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Mostofa Rafid Uddin , Mahek Vora , Qifeng Wu , Muyuan Chen , Min Xu

Deep neural networks may perform poorly when training datasets are heavily class-imbalanced. Recently, two-stage methods decouple representation learning and classifier learning to improve performance. But there is still the vital issue of…

Computer Vision and Pattern Recognition · Computer Science 2021-04-02 Zhisheng Zhong , Jiequan Cui , Shu Liu , Jiaya Jia