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Tensor factorization has been proved as an efficient unsupervised learning approach for health data analysis, especially for computational phenotyping, where the high-dimensional Electronic Health Records (EHRs) with patients' history of…

Machine Learning · Computer Science 2022-11-04 Jing Ma , Qiuchen Zhang , Jian Lou , Li Xiong , Sivasubramanium Bhavani , Joyce C. Ho

Tensor factorization models offer an effective approach to convert massive electronic health records into meaningful clinical concepts (phenotypes) for data analysis. These models need a large amount of diverse samples to avoid population…

Machine Learning · Computer Science 2017-10-13 Yejin Kim , Jimeng Sun , Hwanjo Yu , Xiaoqian Jiang

Computational phenotyping allows for unsupervised discovery of subgroups of patients as well as corresponding co-occurring medical conditions from electronic health records (EHR). Typically, EHR data contains demographic information,…

Machine Learning · Computer Science 2023-10-18 Florian Becker , Age K. Smilde , Evrim Acar

The increased availability of electronic health records (EHRs) have spearheaded the initiative for precision medicine using data driven approaches. Essential to this effort is the ability to identify patients with certain medical conditions…

Healthcare industries frequently handle sensitive and proprietary data, and due to strict privacy regulations, they are often reluctant to share data directly. In today's context, Federated Learning (FL) stands out as a crucial remedy,…

Quantum Physics · Physics 2024-07-08 Amandeep Singh Bhatia , David E. Bernal Neira

Phenotyping electronic health records (EHR) focuses on defining meaningful patient groups (e.g., heart failure group and diabetes group) and identifying the temporal evolution of patients in those groups. Tensor factorization has been an…

Machine Learning · Computer Science 2019-11-15 Ardavan Afshar , Ioakeim Perros , Haesun Park , Christopher deFilippi , Xiaowei Yan , Walter Stewart , Joyce Ho , Jimeng Sun

Non-negative tensor factorization has been shown a practical solution to automatically discover phenotypes from the electronic health records (EHR) with minimal human supervision. Such methods generally require an input tensor describing…

Machine Learning · Computer Science 2020-11-13 Kejing Yin , William K. Cheung , Benjamin C. M. Fung , Jonathan Poon

Data privacy is an important issue for organizations and enterprises to securely outsource data storage, sharing, and computation on clouds / fogs. However, data encryption is complicated in terms of the key management and distribution;…

Cryptography and Security · Computer Science 2021-01-13 Jenn-Bing Ong , Wee-Keong Ng , Ivan Tjuawinata , Chao Li , Jielin Yang , Sai None Myne , Huaxiong Wang , Kwok-Yan Lam , C. -C. Jay Kuo

Federated learning is an emerging distributed machine learning framework aiming at protecting data privacy. Data heterogeneity is one of the core challenges in federated learning, which could severely degrade the convergence rate and…

Machine Learning · Statistics 2025-11-27 Feifei Wang , Huiyun Tang , Yang Li

Machine learning on large-scale genomic or transcriptomic data is important for many novel health applications. For example, precision medicine tailors medical treatments to patients on the basis of individual biomarkers, cellular and…

Machine Learning · Computer Science 2025-05-26 Anika Hannemann , Jan Ewald , Leo Seeger , Erik Buchmann

It has been recently shown that sparse, nonnegative tensor factorization of multi-modal electronic health record data is a promising approach to high-throughput computational phenotyping. However, such approaches typically do not leverage…

Machine Learning · Computer Science 2018-08-09 Jette Henderson , Bradley A. Malin , Joyce C. Ho , Joydeep Ghosh

Protecting sensitive health data while enabling collaborative analysis is a central challenge in healthcare. Traditional machine learning (ML) requires institutions to pool anonymized patient records, centralizing analytical development and…

Machine Learning · Computer Science 2026-05-05 Gaurang Sharma , Juha Pajula , Aada Illikainen , Markus Rautell , Noora Lipsonen , Petri Alhainen , Mika Hilvo

Due to patient privacy protection concerns, machine learning research in healthcare has been undeniably slower and limited than in other application domains. High-quality, realistic, synthetic electronic health records (EHRs) can be…

Machine Learning · Computer Science 2023-02-10 Huan He , Shifan Zhao , Yuanzhe Xi , Joyce C Ho

In many signal processing and machine learning applications, datasets containing private information are held at different locations, requiring the development of distributed privacy-preserving algorithms. Tensor and matrix factorizations…

Machine Learning · Statistics 2019-04-23 Hafiz Imtiaz , Anand D. Sarwate

Tensor decomposition is an effective tool for learning multi-way structures and heterogeneous features from high-dimensional data, such as the multi-view images and multichannel electroencephalography (EEG) signals, are often represented by…

Machine Learning · Computer Science 2022-06-29 Wanguang Yin , Youzhi Qu , Zhengming Ma , Quanying Liu

Homomorphic encryption is a very useful gradient protection technique used in privacy preserving federated learning. However, existing encrypted federated learning systems need a trusted third party to generate and distribute key pairs to…

Cryptography and Security · Computer Science 2020-11-26 Hangyu Zhu , Rui Wang , Yaochu Jin , Kaitai Liang , Jianting Ning

Electronic Health Records (EHRs) are rich sources of patient-level data, offering valuable resources for medical data analysis. However, privacy concerns often restrict access to EHRs, hindering downstream analysis. Current EHR…

Machine Learning · Computer Science 2024-12-03 Muhang Tian , Bernie Chen , Allan Guo , Shiyi Jiang , Anru R. Zhang

Background: The increasing adoption of electronic health records (EHR) across the US has created troves of computable data, to which machine learning methods have been applied to extract useful insights. EHR data, represented as a…

Machine Learning · Computer Science 2021-12-28 Francisco Y Cai , Chengsheng Mao , Yuan Luo

Decentralized learning is an efficient emerging paradigm for boosting the computing capability of multiple bounded computing agents. In the big data era, performing inference within the distributed and federated learning (DL and FL)…

Multiagent Systems · Computer Science 2022-05-11 Mohamed Ridha Znaidi , Gaurav Gupta , Paul Bogdan

We propose a privacy-aware hybrid framework for federated medical image classification that combines tensor-network representation learning, MPC-secured aggregation, and post-aggregation quantum refinement. The framework is motivated by two…

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