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Myosin motor proteins drive vigorous steady-state fluctuations in the actin cytoskeleton of cells. Endogenous embedded semiflexible filaments such as microtubules, or added filaments such as single-walled carbon nanotubes are used as novel…

Biological Physics · Physics 2016-06-21 J. Gladrow , N. Fakhri , F. C. MacKintosh , C. F. Schmidt , C. P. Broedersz

This paper compares simulation results and experimental published data concerning the interaction between $\alpha_2\beta_1$ integrin and collagen.This phenomenon is characterized by a competition among steric, reciprocal orientation…

Biomolecules · Quantitative Biology 2015-05-12 Patrizio Ansalone

The interaction of fluid membranes with a scaffold, which can be a planar surface or a more complex structure, is intrinsic to a number of systems - from artificial supported bilayers and vesicles to cellular membranes. In principle, these…

Soft Condensed Matter · Physics 2014-05-07 Daniel Schmidt , Cornelia Monzel , Timo Bihr , Rudolf Merkel , Udo Seifert , Kheya Sengupta , Ana-Sunčana Smith

Cell adhesion proteins are transmembrane proteins that bind cells to their environment. These proteins typically cluster into disk-shaped or linear structures. Here we show that such clustering patterns spontaneously emerge when the protein…

Soft Condensed Matter · Physics 2023-07-10 Shao-Zhen Lin , Rishita Changede , Michael P. Sheetz , Jacques Prost , Jean-Francois Rupprecht

The paper presents new results on localisation and transmission of flexural waves in a structured plate containing a semi-infinite two-dimensional array of rigid pins. In particular, surface waves are identified and studied at the interface…

A Fermi-liquid (FL) with spin-orbit coupling (SOC) supports a special type of collective modes--chiral spin waves--which are oscillations of magnetization even in the absence of the external magnetic field. We study the chiral spin waves of…

Mesoscale and Nanoscale Physics · Physics 2017-05-03 Abhishek Kumar , Dmitrii L. Maslov

When a fluid flows past a solid surface, its macroscopic motion arises from a subtle interplay between microscopic hydrodynamic and thermodynamic effects at the fluid-solid interface. Classical hydrodynamic models often rely on an…

Fluid Dynamics · Physics 2026-02-04 Haodong Zhang , Fei Wang , Britta Nestler

We explore how inherent flexibility of a protein molecule influences the mechanism controlling the kinetics of allosteric transitions using a variational model inspired from work in protein folding. The striking differences in the predicted…

Quantitative Methods · Quantitative Biology 2009-11-13 Swarnendu Tripathi , John J. Portman

Many biological materials consist of sparse networks of disordered fibres, embedded in a soft elastic matrix. The interplay between rigid and soft elements in such composite networks leads to mechanical properties that can go far beyond the…

Soft Condensed Matter · Physics 2017-04-26 Jan Maarten van Doorn , Luuk Lageschaar , Joris Sprakel , Jasper van der Gucht

A Potts associative memory network has been proposed as a simplified model of macroscopic cortical dynamics, in which each Potts unit stands for a patch of cortex, which can be activated in one of S local attractor states. The internal…

Adaptation and Self-Organizing Systems · Physics 2012-03-07 Eleonora Russo , Alessandro Treves

Interfacial hydration structures are crucial in wide-ranging applications, including battery, colloid, lubrication etc. Multivalent ions like Mg2+ and La3+ show irreplaceable roles in these applications, which are hypothesized due to their…

Chemical Physics · Physics 2024-06-28 Han Li , Zhi Xu , Jiacheng Li , Alessandro Siria , Ming Ma

Sliding along frictional interfaces separating dissimilar elastic materials is qualitatively different from sliding along interfaces separating identical materials due to the existence of an elastodynamic coupling between interfacial slip…

Materials Science · Physics 2017-12-07 Michael Aldam , Shiqing Xu , Efim A. Brener , Yehuda Ben-Zion , Eran Bouchbinder

When a flexible filament is confined to a fluid interface, the balance between capillary attraction, bending resistance, and tension from an external source can lead to a self-buckling instability. We perform an analysis of this instability…

Soft Condensed Matter · Physics 2013-02-12 Arthur A. Evans , Saverio E. Spagnolie , Denis Bartolo , Eric Lauga

The toe pads of frogs consist of soft hexagonal structures and a viscous liquid contained between and within the hexagonal structures. It has been hypothesized that this configuration creates adhesion by allowing for long range capillary…

Soft Condensed Matter · Physics 2017-06-12 A. Tulchinsky , A. D. Gat

The cytoskeleton is a model active matter system that controls diverse cellular processes from division to motility. While both active actomyosin dynamics and actin-microtubule interactions are key to the cytoskeleton's versatility and…

Buckling plays a critical role in the transport and dynamics of elastic microfilaments in Stokesian fluids. However, previous work has only considered filaments with homogeneous structural properties. Filament backbone stiffness can be…

Soft Condensed Matter · Physics 2023-01-20 Thomas Nguyen , Harishankar Manikantan

We demonstrate that an array of discrete waveguides on a slab substrate, both featuring the $\chi^{2}$ nonlinearity, supports stable solitons composed of discrete and continuous components. Two classes of fundamental composite solitons are…

Pattern Formation and Solitons · Physics 2009-11-11 Nicolae C. Panoiu , Richard M. Osgood , Boris A. Malomed

Adhesion between a T cell and an antigen presenting cell is achieved by TCR-pMHC and LFA1-ICAM1 protein complexes. These segregate to form a special pattern, known as the immunological synapse (IS), consisting of a central quasi-circular…

Soft Condensed Matter · Physics 2017-10-06 Nadiv Dharan , Oded Farago

Cooperative binding affects many processes in biology, but it is commonly addressed only in equilibrium. In this work we explore dynamical cooperativity in driven systems, where the cooperation occurs because some of the bonds change the…

Biological Physics · Physics 2015-05-13 Jørgen Kjoshagen Trømborg , Alfredo Alexander-Katz

The interaction of the actin cytoskeleton with cell-substrate adhesions is necessary for cell migration. While the trajectories of motile cells have a stochastic character, investigations of cell motility mechanisms rarely elaborate on the…

Quantitative Methods · Quantitative Biology 2019-03-21 Aydar Uatay