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The outstanding progress in nanostructure fabrication and cooling technologies allows what was unthinkable a few decades ago: bringing single-mode mechanical vibrations to the quantum regime. The coupling between photon and phonon…

Quantum Physics · Physics 2015-10-14 H. Flayac , M. Minkov , V. Savona

Surface-Enhanced Raman Scattering (SERS) allows for detection and identification of molecular vibrational fingerprints in minute sample quantities. The SERS process can be also exploited for optical manipulation of molecular vibrations. We…

We report measurements of vibrational mode shapes of mechanical resonators made from ultrathin carbon nanomembranes (CNMs) with a thickness of approximately 1 nm. CNMs are prepared from electron irradiation induced cross-linking of aromatic…

Materials Science · Physics 2018-04-30 Xianghui Zhang , Reimar Waitz , Fan Yang , Carolin Lutz , Polina Angelova , Armin Gölzhäuser , Elke Scheer

Optical circuits and light sources, such as lasers, undergo continuous miniaturization. In its extreme, nanolasers might be comprised of only a few molecules confined in plasmonic nanoresonators. Few-emitter lasers promise low energy…

Quantum Physics · Physics 2026-05-08 Kai Müller , Kimmo Luoma , Christian Schäfer

The ability to precisely visualize the atomic geometry of the interactions between a drug and its protein target in structural models is critical in predicting the correct modifications in previously identified inhibitors to create more…

Biomolecules · Quantitative Biology 2018-08-14 Erick Martins Ratamero , Dom Bellini , Christopher G. Dowson , Rudolf A. Roemer

Magnetic resonance imaging (MRI) relies on radiofrequency (RF) excitation of proton spin. Clinical diagnosis requires a comprehensive collation of biophysical data via multiple MRI contrasts, acquired using a series of RF sequences that…

Medical Physics · Physics 2025-12-24 Dinor Nagar , Moritz Zaiss , Or Perlman

We present a theoretical investigation of photonuclear tomography as a novel technique for probing the internal structure of nuclei. In this approach, ultraperipheral heavy-ion collisions (UPCs) serve as a source of intense fluxes of…

Nuclear Theory · Physics 2025-08-29 J. D. Baker , C. A. Bertulani , Victor P. Goncalves

All-atom and coarse-grained molecular dynamics are two widely used computational tools to study the conformational states of proteins. Yet, these two simulation methods suffer from the fact that without access to supercomputing resources,…

Quantitative Methods · Quantitative Biology 2022-06-13 Gregory Schwing , Luigi L. Palese , Ariel Fernández , Loren Schwiebert , Domenico L. Gatti

Pathologies associated with calcified tissue, such as osteoporosis, demand in vivo and/or in situ spectroscopic analysis to assess the role of chemical substitutions in the inorganic component. High energy X-ray or NMR spectroscopies are…

Spectroscopy is a crucial laboratory technique for understanding quantum systems through their interactions with electromagnetic radiation. Particularly, spectroscopy is capable of revealing the physical structure of molecules, leading to…

Quantum Physics · Physics 2018-05-24 Ling Hu , YueChi Ma , Y. Xu , W. Wang , Y. Ma , K. Liu , M. -H. Yung , L. Sun

The detection of ensembles of spins under ambient conditions has revolutionized the biological, chemical, and physical sciences through magnetic resonance imaging and nuclear magnetic resonance. Pushing sensing capabilities to the…

Mesoscale and Nanoscale Physics · Physics 2013-04-05 M. S. Grinolds , S. Hong , P. Maletinsky , L. Luan , M. D. Lukin , R. L. Walsworth , A. Yacoby

When studying multi-body protein complexes, biochemists use computational tools that can suggest hundreds or thousands of their possible spatial configurations. However, it is not feasible to experimentally verify more than only a very…

Human-Computer Interaction · Computer Science 2019-09-25 Katarína Furmanová , Adam Jurčík , Barbora Kozlíková , Helwig Hauser , Jan Byška

A virtual vibrational spectrometer, based on efficient software exploring unrestricted Hartree-Fock approximation, has been proposed to perform computational spectroscopy of radicals. The computational device allows obtaining spectra of IR…

Chemical Physics · Physics 2020-08-26 Elena F. Sheka , V. A. Popova

We report on the fabrication and operation of a multi-element vibrational structure consisting of two graphene mechanical resonators coupled by a nanotube beam. The whole structure is suspended. Each graphene resonator is clamped by two…

Mesoscale and Nanoscale Physics · Physics 2013-10-22 I. Tsioutsios , J. Moser , J. A. Plaza , A. Bachtold

For localized and oriented vibrationally excited molecules, the one-body probability density of the nuclei (one-nucleus density) is studied. Like the familiar and widely used one-electron density that represents the probability of finding…

Chemical Physics · Physics 2019-02-21 Axel Schild

Imaging the vibrations of nanomechanical resonators means measuring their flexural mode shapes from the dependence of their frequency response on in-plane position. Applied to two-dimensional resonators, this technique provides a wealth of…

We present a simple one-pot co-assembly method for the synthesis of hierarchically structured pigment particles consisting of silica inverse-opal bricks that are doped with plasmonic absorbers. We study the interplay between the plasmonic…

There have been continuous efforts to seek for novel functional two-dimensional semiconductors with high performance for future applications in nanoelectronics and optoelectronics. In this work, we introduce a successful experimental…

Nuclear Magnetic Resonance (NMR) spectroscopy is the cornerstone of small-molecule structure elucidation. While deep learning has demonstrated significant potential in automating structure elucidation and spectral simulation, current…

Computational Engineering, Finance, and Science · Computer Science 2026-01-23 Zheng Fang , Chen Yang , Hai-tao Yu , Haoming Luo , Haitao He , Jiaqing Xie , Zhuo Yang , Jun Xia

Frequency modulation (FM) Atomic Force Microscopy (AFM) with metal tips functionalized with a CO molecule at the tip apex has provided access to the internal structure of molecules with totally unprecedented resolution. We propose a model…

Materials Science · Physics 2022-05-03 Jaime Carracedo-Cosme , Rubén Pérez