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This research paper outlines the development and implementation of a novel Clinical Decision Support System (CDSS) that integrates AI predictive modeling with medical knowledge bases. It utilizes the quantifiable information elements in lab…

Artificial Intelligence · Computer Science 2026-03-17 Muhammad Hammad Maqsood , Mubashir Sajid , Khubaib Ahmed , Muhammad Usamah Shahid , Muddassar Farooq

Cardiotoxicity induced by cancer treatment has become a major clinical concern, affecting the long-term survival and quality of life of cancer patients. Effective clinical decision-making, including the detection of cancer treatment-induced…

Human-Computer Interaction · Computer Science 2024-08-08 Siyi Wu , Weidan Cao , Shihan Fu , Bingsheng Yao , Ziqi Yang , Changchang Yin , Varun Mishra , Daniel Addison , Ping Zhang , Dakuo Wang

The aim of a clinical decision support tool is to reduce the complexity of clinical decisions. However, when decision support tools are poorly implemented they may actually confuse physicians and complicate clinical care. This paper argues…

Human-Computer Interaction · Computer Science 2020-03-03 Teus H. Kappen , Mirko Noordegraaf , Wilton A. van Klei , Karel G. M. Moons , Cor J. Kalkman

As artificial intelligence (AI) becomes increasingly embedded in healthcare delivery, this chapter explores the critical aspects of developing reliable and ethical Clinical Decision Support Systems (CDSS). Beginning with the fundamental…

Artificial Intelligence · Computer Science 2025-02-18 Muhammet Alkan , Idris Zakariyya , Samuel Leighton , Kaushik Bhargav Sivangi , Christos Anagnostopoulos , Fani Deligianni

Scientific publications about machine learning in healthcare are often about implementing novel methods and boosting the performance - at least from a computer science perspective. However, beyond such often short-lived improvements, much…

The automation of the medical evidence acquisition and diagnosis process has recently attracted increasing attention in order to reduce the workload of doctors and democratize access to medical care. However, most works proposed in the…

Computation and Language · Computer Science 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Julien Martel , Zhi Wen , Gaetan Marceau Caron , Joumana Ghosn

Clinical decision-making is a feedback system where risk estimates influence treatment, which in turn changes disease trajectories, and both shape clinicians' measurement practices. Static prediction often fails clinically: models trained…

Artificial Intelligence · Computer Science 2026-05-19 Pujun Feng , Xiaoyu Guo , Seyed Ehsan Saffari , Min Hun Lee , Siew-Kei Lam , Erik Cambria , Xibin Sun , Yangtao Zhou , Tong Yang , Xiaoyu Zhang , Tao Tan , Yue Sun , Bin Cui

Adopting a good health information system (HIS) is essential for providing high-quality healthcare. With rapid advances in technology in the healthcare industry in recent years, healthcare providers seek effective options to deal with…

Computers and Society · Computer Science 2022-07-26 Soliman S M Aljarboa , Shah J Miah

Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis…

Computation and Language · Computer Science 2025-05-21 Kevin Wu , Eric Wu , Rahul Thapa , Kevin Wei , Angela Zhang , Arvind Suresh , Jacqueline J. Tao , Min Woo Sun , Alejandro Lozano , James Zou

A third of adults in America use the Internet to diagnose medical concerns, and online symptom checkers are increasingly part of this process. These tools are powered by diagnosis models similar to clinical decision support systems, with…

Machine Learning · Computer Science 2019-12-18 Anitha Kannan , Jason Alan Fries , Eric Kramer , Jen Jen Chen , Nigam Shah , Xavier Amatriain

Clinical diagnosis is critical in medical practice, typically requiring a continuous and evolving process that includes primary diagnosis, differential diagnosis, and final diagnosis. However, most existing clinical diagnostic tasks are…

Artificial Intelligence · Computer Science 2024-12-17 Ruihui Hou , Shencheng Chen , Yongqi Fan , Guangya Yu , Lifeng Zhu , Jing Sun , Jingping Liu , Tong Ruan

Medical imaging is an essential tool for diagnosing various healthcare diseases and conditions. However, analyzing medical images is a complex and time-consuming task that requires expertise and experience. This article aims to design a…

Image and Video Processing · Electrical Eng. & Systems 2023-05-15 Ayyub Alzahem , Shahid Latif , Wadii Boulila , Anis Koubaa

Major advances have been made regarding the utilization of artificial intelligence in health care. In particular, deep learning approaches have been successfully applied for automated and assisted disease diagnosis and prognosis based on…

Methodology · Statistics 2020-03-24 Max Westphal , Antonia Zapf , Werner Brannath

Background: Clinical decision support systems (CDSS) are a category of health information technologies that can assist clinicians to choose optimal treatments. These support systems are based on clinical trials and expert knowledge;…

Clinical decision support systems (CDSS) are widely used to assist with medical decision making. However, CDSS typically require manually curated rules and other data which are difficult to maintain and keep up-to-date. Recent systems…

Human-Computer Interaction · Computer Science 2020-11-20 Zhuochen Jin , Jingshun Yang , Shuyuan Cui , David Gotz , Jimeng Sun , Nan Cao

Clinical decision support systems are software tools that help clinicians to make medical decisions. However, their acceptance by clinicians is usually rather low. A known problem is that they often require clinicians to manually enter lots…

Artificial Intelligence · Computer Science 2023-09-20 Jean-Baptiste Lamy , Abdelmalek Mouazer , Karima Sedki , Sophie Dubois , Hector Falcoff

Clinical Decision Support Systems (CDSS) utilize evidence-based knowledge and patient data to offer real-time recommendations, with Large Language Models (LLMs) emerging as a promising tool to generate plain-text explanations for medical…

Computation and Language · Computer Science 2023-10-04 D. Umerenkov , G. Zubkova , A. Nesterov

There is a growing need to understand how digital systems can support clinical decision-making, particularly as artificial intelligence (AI) models become increasingly complex and less human-interpretable. This complexity raises concerns…

The paper presents an approach for building consistent and applicable clinical decision support systems (CDSSs) using a data-driven predictive model aimed at resolving the problem of low applicability and scalability of CDSSs in real-world…

Artificial Intelligence · Computer Science 2022-02-18 Sergey V. Kovalchuk , Georgy D. Kopanitsa , Ilia V. Derevitskii , Daria A. Savitskaya

In early clinical test evaluations the potential benefits of the introduction of a new technology into the healthcare system are assessed in the challenging situation of limited available empirical data. The aim of these evaluations is to…

Applications · Statistics 2020-05-21 Sara Graziadio , Kevin J. Wilson
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