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In clinical CT, the x-ray source emits polychromatic x-rays, which are detected in the current-integrating mode. This physical process is accurately described by an energy-dependent non-linear integral model on the basis of the Beer-Lambert…

Medical Physics · Physics 2018-01-11 Wenxiang Cong , Ge Wang

Deep learning based computed tomography (CT) reconstruction has demonstrated outstanding performance on simulated 2D low-dose CT data. This applies in particular to domain adapted neural networks, which incorporate a handcrafted physics…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Jevgenija Rudzusika , Buda Bajić , Thomas Koehler , Ozan Öktem

Data augmentation can effectively resolve a scarcity of images when training machine-learning algorithms. It can make them more robust to unseen images. We present a lesion conditional Generative Adversarial Network LcGAN to generate…

Image and Video Processing · Electrical Eng. & Systems 2020-08-10 Manohar Karki , Junghwan Cho , Seokhwan Ko

Dual-energy computed tomography (CT) is to reconstruct images of an object from two projection datasets generated from two distinct x-ray source energy spectra. It can provide more accurate attenuation quantification than conventional CT…

Medical Physics · Physics 2018-05-15 Wenxiang Cong , Daniel Harrison , Yan Xi , Ge Wang

Positron Emission Tomography (PET) is a vital imaging modality widely used in clinical diagnosis and preclinical research but faces limitations in image resolution and signal-to-noise ratio due to inherent physical degradation factors.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-11 Boxiao Yu , Kuang Gong

Photomultiplier tubes (PMTs) are widely employed in particle and nuclear physics experiments. The accuracy of PMT waveform reconstruction directly impacts the detector's spatial and energy resolution. A key challenge arises when multiple…

High Energy Physics - Experiment · Physics 2026-02-06 Kainan Liu , Jingyu Huang , Guihong Huang , Jianyi Luo

To obtain high-quality Positron emission tomography (PET) images while minimizing radiation exposure, numerous methods have been proposed to reconstruct standard-dose PET (SPET) images from the corresponding low-dose PET (LPET) images.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-10 Jiaqi Cui , Yan Wang , Lu Wen , Pinxian Zeng , Xi Wu , Jiliu Zhou , Dinggang Shen

In this work we present a novel system for PET estimation using CT scans. We explore the use of fully convolutional networks (FCN) and conditional generative adversarial networks (GAN) to export PET data from CT data. Our dataset includes…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Avi Ben-Cohen , Eyal Klang , Stephen P. Raskin , Michal Marianne Amitai , Hayit Greenspan

The use of CT imaging is important for screening, diagnosis, therapy planning, and prognosis of lung cancers. Unfortunately, due to differences in imaging protocols and scanner models, CT images acquired by different means may show large…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Md Shifatul Ahsan Apurba , Md Selim , Jin Chen

Quantitative imaging is an important feature of spectral X-ray and CT systems, especially photon-counting CT (PCCT) imaging systems, which is achieved through material decomposition (MD) using spectral measurements. In this work, we present…

Medical Physics · Physics 2026-03-04 Sen Wang , Yirong Yang , Jooho Lee , Grant M. Stevens , Adam S. Wang

Purpose: To evaluate a proposed method to reconstruct CT numbers that accurately mimic conventional CT numbers from spectral CT data, as would have been produced by a conventional system without effects of beam hardening. Approach: We…

Medical Physics · Physics 2022-08-10 Fredrik Grönberg , Hans Bornefalk

This paper applies the recent fast iterative neural network framework, Momentum-Net, using appropriate models to low-dose X-ray computed tomography (LDCT) image reconstruction. At each layer of the proposed Momentum-Net, the model-based…

Image and Video Processing · Electrical Eng. & Systems 2020-09-10 Siqi Ye , Yong Long , Il Yong Chun

Two algorithms for solving misalignment issues in penalized PET/CT reconstruction using anatomical priors are proposed. Both approaches are based on a recently published joint motion estimation and image reconstruction method. The first…

Imitation learning considerably simplifies policy synthesis compared to alternative approaches by exploiting access to expert demonstrations. For such imitation policies, errors away from the training samples are particularly critical. Even…

Machine Learning · Computer Science 2024-03-19 Kaustubh Sridhar , Souradeep Dutta , Dinesh Jayaraman , James Weimer , Insup Lee

One of the major challenges in design and developing of PET, scanners are the presence of inactive areas between the detector blocks which degrade the image spatial resolution and leads to streaking artifacts especially when we employ…

Medical Physics · Physics 2019-06-19 Isaac Shiri , Peyman Sheikhzadeh , Mohammad Reza Ay

Magnetic resonance imaging (MRI)-based synthetic computed tomography (sCT) simplifies radiation therapy treatment planning by eliminating the need for CT simulation and error-prone image registration, ultimately reducing patient radiation…

Image and Video Processing · Electrical Eng. & Systems 2023-06-01 Shaoyan Pan , Elham Abouei , Jacob Wynne , Tonghe Wang , Richard L. J. Qiu , Yuheng Li , Chih-Wei Chang , Junbo Peng , Justin Roper , Pretesh Patel , David S. Yu , Hui Mao , Xiaofeng Yang

Differential phase-contrast computed tomography (DPC-CT) is a powerful analysis tool for soft-tissue and low-atomic-number samples. Limited by the implementation conditions, DPC-CT with incomplete projections happens quite often.…

Medical Physics · Physics 2020-07-01 Jianbing Dong , Jian Fu , Zhao He

PET image reconstruction is challenging due to the ill-poseness of the inverse problem and limited number of detected photons. Recently deep neural networks have been widely and successfully used in computer vision tasks and attracted…

Computer Vision and Pattern Recognition · Computer Science 2017-10-11 Kuang Gong , Jiahui Guan , Kyungsang Kim , Xuezhu Zhang , Georges El Fakhri , Jinyi Qi , Quanzheng Li

Dynamic positron emission tomography (PET) reconstruction often presents high noise due to the use of short duration frames to describe the kinetics of the radiotracer. Here we introduce a new method to calculate a kernel matrix to be used…

Medical Physics · Physics 2026-01-01 Alan Miranda , Steven Staelens

We propose in this work a framework for synergistic positron emission tomography (PET)/computed tomography (CT) reconstruction using a joint generative model as a penalty. We use a synergistic penalty function that promotes PET/CT pairs…

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