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Sensing of a few unpaired electron spins, such as metal ions and radicals, is a useful but difficult task in nanoscale physics, biology, and chemistry. Single nitrogen-vacancy (NV) centers in diamond offer high sensitivity and spatial…

Mesoscale and Nanoscale Physics · Physics 2018-08-13 F. Gorrini , R. Giri , C. E. Avalos , S. Tambalo , S. Mannucci , L. Basso , N. Bazzanella , C. Dorigoni , M. Cazzanelli , P. Marzola , A. Miotello , A. Bifone

Nitrogen-vacancy (NV) centers in nanodiamonds are excellent nanoscale sensors for measuring parameters such as temperature, magnetic field, and viscosity in complex fluidic environments, including living cells. However, the rapid motion of…

Owing to the unique electronic spin properties, the nitrogen-vacancy (NV) centers hosted in diamond have emerged as a powerful quantum sensor for various physical parameters and biological species. In this work, a miniature optical-fiber…

Photonic spin density (PSD) in the near-field gives rise to exotic phenomena such as photonic skyrmions, optical spin-momentum locking and unidirectional topological edge waves. Experimental investigation of these phenomena requires a…

Quantum Physics · Physics 2021-10-04 Farid Kalhor , Li-Ping Yang , Leif Bauer , Zubin Jacob

Dopamine levels are linked to neurological illnesses like Parkinson's and Alzheimer's. Thus, reliable and sensitive detection of dopamine is crucial for early diagnosis and surveillance of neurodegenerative diseases. Non-noble-metal-based…

Paramagnetic magnetic resonance, a powerful technique for characterizing and identifying chemical targets, is increasingly used for imaging; however, low spin polarization at room temperature and moderate magnetic fields poses challenges…

Mesoscale and Nanoscale Physics · Physics 2019-09-04 C. M. Purser , V. P. Bhallamudi , C. S. Wolfe , H. Yusuf , B. A. McCullian , C. Jayaprakash , M. E. Flatté , P. C. Hammel

An important tool in the investigation of the early stages of neurodegenerative disease is the study of dissected living tissue from the brain of an animal model. Such investigations allow the physical structure of individual neurons and…

Nitrogen-vacancy (NV) based quantum sensors hold great potential for real-time single-cell sensing with far-reaching applications in fundamental biology and medical diagnostics. Although highly sensitive, the mapping of quantum measurements…

Nitrogen-vacancy (NV) centers in diamond are a leading modality for magnetic sensing and imaging under ambient conditions. However, these sensors suffer from degraded performance due to paramagnetic impurities and regions of stress in the…

Quantum Physics · Physics 2024-04-22 Connor Roncaioli , Connor Hart , Ronald Walsworth , Donald P. Fahey

Sensing of signals from biological processes, such as action potential propagation in nerves, are essential for clinical diagnosis and basic understanding of physiology. Sensing can be performed electrically by placing sensor probes near or…

Biocompatible nanoscale probes for sensitive detection of paramagnetic species and molecules associated with their (bio)chemical transformations would provide a desirable tool for a better understanding of cellular redox processes. Here, we…

We report on a novel flow-based method for high-precision chemical detection that integrates quantum sensing with droplet microfluidics. We deploy nanodiamond particles hosting fluorescent nitrogen vacancy defects as quantum sensors in…

The integration of light and materials technology is key to the creation of innovative sensing technologies. Sensing of electric and magnetic fields, and temperature with high spatio-temporal resolution is a critical task for the…

The protocols for the control and readout of Nitrogen Vacancy (NV) centres electron spins in diamond offer an advanced platform for quantum computation, metrology and sensing. These protocols are based on the optical readout of photons…

Mesoscale and Nanoscale Physics · Physics 2019-06-26 E. Bourgeois , A. Jarmola , M. Gulka , J. Hruby , D. Budker , M. Nesladek

Spin relaxometry using fluorescent nanodiamonds (FNDs) has been applied successfully to sense numerous paramagnetic target molecules such as free radicals and metalloproteins. However, despite their high sensitivity, T1 spin relaxation…

Mesoscale and Nanoscale Physics · Physics 2026-02-23 Trent Ralph , Erin S. Grant , Lianne Lay , Sepehr Ahmadi , David A. Simpson

Optically accessible spin-active nanomaterials are promising as quantum nanosensors for probing biological samples. However, achieving bioimaging-level brightness and high-quality spin properties for these materials is challenging and…

Recently significant attention has been paid to magnetic-field-dependent photoluminescence (PL) features of the negatively charged nitrogen-vacancy (NV) centers in diamond. These features are used for microwave-free sensing and are…

Quantum Physics · Physics 2024-09-24 Irena Rodzoń , Xue Zhang , Viktor Ivády , Huijie Zheng , Arne Wickenbrock , Dmitry Budker

The investigation of paramagnetic species (such as point defects, dopants, and impurities) in solid-state electronic devices is significant because of their effect on device performance. Conventionally, these species are detected and imaged…

Materials Science · Physics 2015-05-20 Itai Katz , Matthias Fehr , Alexander Schnegg , Klaus Lips , Aharon Blank

The detection of physiological activity at the microscopic level is key for understanding the function of biosystems and relating this to physical structure. Current sensing methods often rely on invasive probes to stimulate and detect…

Probing electrical and magnetic properties in aqueous environments remains a frontier challenge in nanoscale sensing. Our inability to do so with quantitative accuracy imposes severe limitations, for example, on our understanding of the…

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