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Cell nuclei segmentation is one of the most important tasks in the analysis of biomedical images. With ever-growing sizes and amounts of three-dimensional images to be processed, there is a need for better and faster segmentation methods.…

Computer Vision and Pattern Recognition · Computer Science 2017-02-20 Julian Arz , Peter Sanders , Johannes Stegmaier , Ralf Mikut

With the increasing popularity of calcium imaging data in neuroscience research, methods for analyzing calcium trace data are critical to address various questions. The observed calcium traces are either analyzed directly or deconvolved to…

Neurons and Cognition · Quantitative Biology 2021-03-04 Tong Shen , Gyorgy Lur , Xiangmin Xu , Zhaoxia Yu

Deep learning models (DLMs) frequently achieve accurate segmentation and classification of tumors from medical images. However, DLMs lacking feedback on their image segmentation mechanisms, such as Dice coefficients and confidence in their…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Elhoucine Elfatimi , Pratik Shah

Models based on deep convolutional neural networks (CNN) have significantly improved the performance of semantic segmentation. However, learning these models requires a large amount of training images with pixel-level labels, which are very…

Computer Vision and Pattern Recognition · Computer Science 2018-02-05 Linwei Ye , Zhi Liu , Yang Wang

Z-disks are complex structures that delineate repeating sarcomeres in striated muscle. They play significant roles in cardiomyocytes such as providing mechanical stability for the contracting sarcomere, cell signalling and autophagy.…

Image and Video Processing · Electrical Eng. & Systems 2024-01-25 Mihaela Croitor Ibrahim , Nishant Ravikumar , Alistair Curd , Joanna Leng , Oliver Umney , Michelle Peckham

Accurate cell segmentation in pathology images typically requires dense pixel-wise annotations, which are costly and time-consuming to obtain. This challenge is especially important for emerging biological imaging modalities and multiplexed…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Gunjan Shrivastava , Saad Nadeem

Skin cancer is a frequently occurring cancer in the human population, and it is very important to be able to diagnose malignant tumors in the body early. Lesion segmentation is crucial for monitoring the morphological changes of skin…

Image and Video Processing · Electrical Eng. & Systems 2023-09-06 Changlu Guo , Jiangyan Dai , Marton Szemenyei , Yugen Yi

Digital pathology is one of the most significant developments in modern medicine. Pathological examinations are the gold standard of medical protocols and play a fundamental role in diagnosis. Recently, with the advent of digital scanners,…

Image and Video Processing · Electrical Eng. & Systems 2021-12-09 Mahdi Arab Loodaricheh , Nader Karimi , Shadrokh Samavi

The accurate segmentation and tracking of cells in microscopy image sequences is an important task in biomedical research, e.g., for studying the development of tissues, organs or entire organisms. However, the segmentation of touching…

Computer Vision and Pattern Recognition · Computer Science 2020-12-10 Tim Scherr , Katharina Löffler , Moritz Böhland , Ralf Mikut

Microcalcifications are small deposits of calcium that appear in mammograms as bright white specks on the soft tissue background of the breast. Microcalcifications may be a unique indication for Ductal Carcinoma in Situ breast cancer, and…

Computer Vision and Pattern Recognition · Computer Science 2021-02-24 Roee Zamir , Shai Bagon , David Samocha , Yael Yagil , Ronen Basri , Miri Sklair-Levy Meirav Galun

A shape filter is presented to repair segmentation results obtained in calcium imaging of neurons in vivo. This post-segmentation algorithm can automatically smooth the shapes obtained from a preliminary segmentation, while precluding the…

Image and Video Processing · Electrical Eng. & Systems 2018-06-04 Jie Wang , Zhongxiao Fu , Nasrin Sadeghzadehyazdi , Jonathan Kipnis , Scott T. Acton

We propose a 3D convolutional neural network to simultaneously segment and detect cell nuclei in confocal microscopy images. Mirroring the co-dependency of these tasks, our proposed model consists of two serial components: the first part…

Image and Video Processing · Electrical Eng. & Systems 2018-09-07 Sundaresh Ram , Vicky T. Nguyen , Kirsten H. Limesand , Mert R. Sabuncu

Automated and semi-automated techniques in biomedical electron microscopy (EM) enable the acquisition of large datasets at a high rate. Segmentation methods are therefore essential to analyze and interpret these large volumes of data, which…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Anusha Aswath , Ahmad Alsahaf , Ben N. G. Giepmans , George Azzopardi

Surgical instrument segmentation (SIS) on endoscopic images stands as a long-standing and essential task in the context of computer-assisted interventions for boosting minimally invasive surgery. Given the recent surge of deep learning…

Computer Vision and Pattern Recognition · Computer Science 2024-11-08 Mingyu Sheng , Jianan Fan , Dongnan Liu , Ron Kikinis , Weidong Cai

The Segment Anything Model (SAM) exhibits a capability to segment a wide array of objects in natural images, serving as a versatile perceptual tool for various downstream image segmentation tasks. In contrast, medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Yizhe Zhang , Tao Zhou , Shuo Wang , Ye Wu , Pengfei Gu , Danny Z. Chen

Deep Neural Networks (DNNs) have shown remarkable success in various computer vision tasks. However, their black-box nature often leads to difficulty in interpreting their decisions, creating an unfilled need for methods to explain the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Daniel Siegismund , Mario Wieser , Stephan Heyse , Stephan Steigele

The semantic segmentation of skin lesions is an important and common initial task in the computer aided diagnosis of dermoscopic images. Although deep learning-based approaches have considerably improved the segmentation accuracy, there is…

Computer Vision and Pattern Recognition · Computer Science 2020-03-24 Kumar Abhishek , Ghassan Hamarneh , Mark S. Drew

The recent surge in performance for image analysis of digitised pathology slides can largely be attributed to the advances in deep learning. Deep models can be used to initially localise various structures in the tissue and hence facilitate…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Simon Graham , Quoc Dang Vu , Mostafa Jahanifar , Shan E Ahmed Raza , Fayyaz Minhas , David Snead , Nasir Rajpoot

3D image segmentation is a recent and crucial step in many medical analysis and recognition schemes. In fact, it represents a relevant research subject and a fundamental challenge due to its importance and influence. This paper provides a…

Image and Video Processing · Electrical Eng. & Systems 2022-07-22 Omar Boudraa

Particle competition and cooperation (PCC) is a graph-based semi-supervised learning approach. When PCC is applied to interactive image segmentation tasks, pixels are converted into network nodes, and each node is connected to its k-nearest…

Computer Vision and Pattern Recognition · Computer Science 2020-02-17 Fabricio Breve