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Estimating the uncertainty in (probabilistic) image registration enables, e.g., surgeons to assess the operative risk based on the trustworthiness of the registered image data. If surgeons receive inaccurately calculated registration…

Computer Vision and Pattern Recognition · Computer Science 2020-04-27 Jie Luo , Alireza Sedghi , Karteek Popuri , Dana Cobzas , Miaomiao Zhang , Frank Preiswerk , Matthew Toews , Alexandra Golby , Masashi Sugiyama , William M. Wells , Sarah Frisken

While linear registration is a critical step in MRI preprocessing pipelines, its numerical uncertainty is understudied. Using Monte-Carlo Arithmetic (MCA) simulations, we assessed the most commonly used linear registration tools within…

Quantitative Methods · Quantitative Biology 2025-09-01 Niusha Mirhakimi , Yohan Chatelain , Tristan Glatard , Jean-Baptiste Poline

Over recent years, deep learning based image registration has achieved impressive accuracy in many domains, including medical imaging and, specifically, human neuroimaging with magnetic resonance imaging (MRI). However, the uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Xiaoling Hu , Karthik Gopinath , Peirong Liu , Malte Hoffmann , Koen Van Leemput , Oula Puonti , Juan Eugenio Iglesias

Being a task of establishing spatial correspondences, medical image registration is often formalized as finding the optimal transformation that best aligns two images. Since the transformation is such an essential component of registration,…

Computer Vision and Pattern Recognition · Computer Science 2017-05-19 Jie Luo , Karteek Popuri , Dana Cobzas , Hongyi Ding , William M. Wells , Masashi Sugiyama

Recent works in medical image registration have proposed the use of Implicit Neural Representations, demonstrating performance that rivals state-of-the-art learning-based methods. However, these implicit representations need to be optimized…

Image and Video Processing · Electrical Eng. & Systems 2023-10-04 Louis D. van Harten , Jaap Stoker , Ivana Išgum

Acquisition-to-acquisition signal intensity variations (non-standardness) are inherent in MR images. Standardization is a post processing method for correcting inter-subject intensity variations through transforming all images from the…

Computer Vision and Pattern Recognition · Computer Science 2015-05-18 Ulas Bagci , Jayaram K. Udupa , Li Bai

Deformable image registration is fundamental to many medical imaging applications. Registration is an inherently ambiguous task often admitting many viable solutions. While neural network-based registration techniques enable fast and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Leonard Siegert , Paul Fischer , Mattias P. Heinrich , Christian F. Baumgartner

Image registration aims to establish spatial correspondence across pairs, or groups of images, and is a cornerstone of medical image computing and computer-assisted-interventions. Currently, most deep learning-based registration methods…

Image and Video Processing · Electrical Eng. & Systems 2021-07-12 Xiang Chen , Nishant Ravikumar , Yan Xia , Alejandro F Frangi

Medical image registration is critical for aligning anatomical structures across imaging modalities such as computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound. Among existing techniques, non-rigid registration (NRR)…

Image and Video Processing · Electrical Eng. & Systems 2025-12-17 Sneha Sree C. , Dattesh Shanbhag , Sudhanya Chatterjee

Image registration is the basis for many applications in the fields of medical image computing and computer assisted interventions. One example is the registration of 2D X-ray images with preoperative three-dimensional computed tomography…

Computer Vision and Pattern Recognition · Computer Science 2020-12-16 Darya Trofimova , Tim Adler , Lisa Kausch , Lynton Ardizzone , Klaus Maier-Hein , Ulrich Köthe , Carsten Rother , Lena Maier-Hein

In this paper, we address the point cloud registration problem, where well-known methods like ICP fail under uncertainty arising from sensor noise, pose-estimation errors, and partial overlap due to occlusion. We develop a novel approach,…

Robotics · Computer Science 2025-09-25 Johannes A. Gaus , Loris Schneider , Yitian Shi , Jongseok Lee , Rania Rayyes , Rudolph Triebel

Accurate image registration is essential in many medical imaging applications, yet most deep registration networks provide little indication of when or where their predictions are unreliable. Existing uncertainty estimation approaches, such…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lin Tian , Xiaoling Hu , Juan Eugenio Iglesias

Image registration is a research field in which images must be compared and aligned independently of the point of view or camera characteristics. In some applications (such as forensic biometrics, satellite photography or outdoor scene…

Computer Vision and Pattern Recognition · Computer Science 2022-07-14 Carlos Francisco Moreno-Garcia , Francesc Serratosa

Deformable medical image registration is an essential task in computer-assisted interventions. This problem is particularly relevant to oncological treatments, where precise image alignment is necessary for tracking tumor growth, assessing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Stefano Fogarollo , Gregor Laimer , Reto Bale , Matthias Harders

During tumor resection surgery, surgeons rely on neuronavigation to locate tumors and other critical structures in the brain. Most neuronavigation is based on preoperative images, such as MRI and ultrasound, to navigate through the brain.…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Mahsa Geshvadi

In healthcare applications, predictive uncertainty has been used to assess predictive accuracy. In this paper, we demonstrate that predictive uncertainty estimated by the current methods does not highly correlate with prediction error by…

Machine Learning · Computer Science 2021-07-08 Shi Hu , Nicola Pezzotti , Max Welling

In order to tackle the difficulty associated with the ill-posed nature of the image registration problem, regularization is often used to constrain the solution space. For most learning-based registration approaches, the regularization…

Computer Vision and Pattern Recognition · Computer Science 2022-03-03 Zhe Xu , Jie Luo , Donghuan Lu , Jiangpeng Yan , Sarah Frisken , Jayender Jagadeesan , William Wells , Xiu Li , Yefeng Zheng , Raymond Tong

Uncertainty estimation methods are expected to improve the understanding and quality of computer-assisted methods used in medical applications (e.g., neurosurgical interventions, radiotherapy planning), where automated medical image…

Computer Vision and Pattern Recognition · Computer Science 2018-06-08 Alain Jungo , Raphael Meier , Ekin Ermis , Marcela Blatti-Moreno , Evelyn Herrmann , Roland Wiest , Mauricio Reyes

Image registration is a widely-used technique in analysing large scale datasets that are captured through various imaging modalities and techniques in biomedical imaging such as MRI, X-Rays, etc. These datasets are typically collected from…

Computer Vision and Pattern Recognition · Computer Science 2020-09-22 Hassan Mahmood , Asim Iqbal , Syed Mohammed Shamsul Islam

Medical image registration is a challenging task involving the estimation of spatial transformations to establish anatomical correspondence between pairs or groups of images. Recently, deep learning-based image registration methods have…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Xiang Chen , Yan Xia , Nishant Ravikumar , Alejandro F Frangi
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