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We study a general setting of neutral evolution in which the population is of finite, constant size and can have spatial structure. Mutation leads to different genetic types ("traits"), which can be discrete or continuous. Under minimal…

Populations and Evolution · Quantitative Biology 2018-11-02 Alex McAvoy , Ben Adlam , Benjamin Allen , Martin A. Nowak

A general multi-type population model is considered, where individuals live and reproduce according to their age and type, but also under the influence of the size and composition of the entire population. We describe the dynamics of the…

Probability · Mathematics 2019-03-13 Jie Yen Fan , Kais Hamza , Peter Jagers , Fima C. Klebaner

Background: The accumulation of deleterious mutations of a population directly contributes to the fate as to how long the population would exist. Muller's ratchet provides a quantitative framework to study the effect of accumulation.…

Populations and Evolution · Quantitative Biology 2011-09-22 Shuyun Jiao , Yanbo Wang , Bo Yuan , Ping Ao

We investigate local-density dependent Markov processes on a class of large graphs sampled from a graphon, where the transition rates of the vertices are influenced by the states of their neighbors. We show that as the average degree…

Probability · Mathematics 2020-11-24 Daniel Keliger , Illes Horvath , Balint Takacs

We study a stochastic branching model for a population structured by a quantitative phenotypic trait and subject to births, deaths, and mutations. In a regime of large population and small mutations, and in logarithmic scales of size and…

Probability · Mathematics 2026-04-21 Nicolas Champagnat , Sylvie Méléard , Sepideh Mirrahimi , Viet Chi Tran

$\Lambda$-Wright--Fisher processes provide a robust framework to describe the type-frequency evolution of an infinite neutral population. We add a polynomial drift to the corresponding stochastic differential equation to incorporate…

Probability · Mathematics 2023-04-26 Fernando Cordero , Sebastian Hummel , Emmanuel Schertzer

The dynamics of adaptation is difficult to predict because it is highly stochastic even in large populations. The uncertainty emerges from number fluctuations, called genetic drift, arising in the small number of particularly fit…

Populations and Evolution · Quantitative Biology 2015-06-30 Oskar Hallatschek , Lukas Geyrhofer

We consider a particle system in continuous time, discrete population, with spatial motion and nonlocal branching. The offspring's weights and their number may depend on the mother's weight. Our setting captures, for instance, the processes…

Probability · Mathematics 2012-10-12 Bertrand Cloez

We present stochastic, finite-population formulations of the Crow-Kimura and Eigen models of quasispecies theory, for fitness functions that depend in an arbitrary way on the number of mutations from the wild type. We include back mutations…

Populations and Evolution · Quantitative Biology 2010-02-23 Jeong-Man Park , Enrique Munoz , Michael W. Deem

We study the multi-strategy stochastic evolutionary game with death-birth updating in expanding spatial populations of size $N\to \infty$. The model is a voter model perturbation. For typical populations, we require perturbation strengths…

Probability · Mathematics 2021-01-13 Yu-Ting Chen

We develop a global and hierarchical scheme for the forward Kolmogorov (Fokker-Planck) equation of the diffusion approximation of the Wright-Fisher model of population genetics. That model describes the random genetic drift of several…

Analysis of PDEs · Mathematics 2015-09-21 Julian Hofrichter , Tat Dat Tran , Jürgen Jost

This chapter focuses on the derivation of a doubly nonlocal Fisher-KPP model, which is a macroscopic nonlocal evolution equation describing population dynamics in the large population limit. The derivation starts from a microscopic…

Analysis of PDEs · Mathematics 2024-06-11 Jasper Hoeksema , Anastasiia Hraivoronska , Oliver Tse

We consider a general interacting particle system with interactions on a random graph, and study the large population limit of this system. When the sequence of underlying graphs converges to a graphon, we show convergence of the…

Probability · Mathematics 2024-10-16 Carla Crucianelli , Ludovic Tangpi

Consider a two-type Moran population of size $N$ with selection and mutation, where the selective advantage of the fit individuals is amplified at extreme environmental conditions. Assume selection and mutation are weak with respect to $N$,…

Probability · Mathematics 2023-04-26 Fernando Cordero , Grégoire Véchambre

We study voter models defined on large sets. Through a perspective emphasizing the martingale property of voter density processes, we prove that in general, their convergence to the Wright-Fisher diffusion only involves certain averages of…

Probability · Mathematics 2013-11-25 Yu-Ting Chen , Jihyeok Choi , J. Theodore Cox

We study the evolution of gene frequencies in a population living in $\mathbb{R}^d$, modelled by the spatial Lambda Fleming-Viot process with natural selection (Barton, Etheridge and Veber, 2010 and Etheridge, Veber and Yu, 2014). We…

Probability · Mathematics 2022-10-04 Raphaël Forien , Sarah Penington

In this note, we investigate fundamental relations between exploration processes in random graphs, and branching processes. We formulate a class of models that we call {\em rank-$k$ random graphs}, and that are special in that their…

Probability · Mathematics 2022-07-26 Suman Chakraborty , Kjell Raaijmakers , Remco van der Hofstad

We consider time-continuous Markovian discrete-state dynamics on random networks of interacting agents and study the large population limit. The dynamics are projected onto low-dimensional collective variables given by the shares of each…

Probability · Mathematics 2026-03-19 Marvin Lücke , Jobst Heitzig , Péter Koltai , Nora Molkenthin , Stefanie Winkelmann

To learn about the past from a sample of genomic sequences, one needs to understand how evolutionary processes shape genetic diversity. Most population genetic inference is based on frameworks assuming adaptive evolution is rare. But if…

Populations and Evolution · Quantitative Biology 2014-03-25 Richard A. Neher

Our principal aim is to observe the Markov discrete-time process of population growth with long-living trajectory. First we study asymptotical decay of generating function of Galton-Watson process for all cases as the Basic Lemma.…

Probability · Mathematics 2020-04-21 Azam A. Imomov
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