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We propose a novel matrix autoencoder to map functional connectomes from resting state fMRI (rs-fMRI) to structural connectomes from Diffusion Tensor Imaging (DTI), as guided by subject-level phenotypic measures. Our specialized autoencoder…

Resting-state functional Magnetic Resonance Imaging (fMRI) is a powerful imaging technique for studying functional development of the brain in utero. However, unpredictable and excessive movement of fetuses has limited clinical application…

The field of neuroimaging has truly become data rich, and novel analytical methods capable of gleaning meaningful information from large stores of imaging data are in high demand. Those methods that might also be applicable on the level of…

Task-based functional magnetic resonance imaging (task fMRI) is a non-invasive technique that allows identifying brain regions whose activity changes when individuals are asked to perform a given task. This contributes to the understanding…

Functional magnetic resonance imaging (fMRI) data is characterized by its complexity and high--dimensionality, encompassing signals from various regions of interests (ROIs) that exhibit intricate correlations. Analyzing fMRI data directly…

Applications · Statistics 2024-01-18 Yeseul Jeon , Jeong-Jae Kim , SuMin Yu , Junggu Choi , Sanghoon Han

The goal of the present study is to identify autism using machine learning techniques and resting-state brain imaging data, leveraging the temporal variability of the functional connections (FC) as the only information. We estimated and…

Neurons and Cognition · Quantitative Biology 2017-12-22 Ravi Tejwani , Adam Liska , Hongyuan You , Jenna Reinen , Payel Das

Fetal brain magnetic resonance imaging (MRI) offers exquisite images of the developing brain but is not suitable for second-trimester anomaly screening, for which ultrasound (US) is employed. Although expert sonographers are adept at…

Image and Video Processing · Electrical Eng. & Systems 2020-08-21 Jianbo Jiao , Ana I. L. Namburete , Aris T. Papageorghiou , J. Alison Noble

Magnetic resonance imaging (MRI) has played a crucial role in fetal neurodevelopmental research. Structural annotations of MR images are an important step for quantitative analysis of the developing human brain, with Deep Learning providing…

The goal of emotional brain state classification on functional MRI (fMRI) data is to recognize brain activity patterns related to specific emotion tasks performed by subjects during an experiment. Distinguishing emotional brain states from…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Maxime Tchibozo , Donggeun Kim , Zijing Wang , Xiaofu He

We investigate whether and how we can improve the cost efficiency of neuroimaging studies with well-tailored fMRI tasks. The comparative study is conducted using a novel network science-driven Bayesian connectome-based predictive method,…

Applications · Statistics 2024-11-05 Xinzhi Zhang , Leslie A Hulvershorn , Todd Constable , Yize Zhao , Selena Wang

Functional MRI measuring BOLD signal is an increasingly important imaging modality in studying brain functions and neurological disorders. It can be acquired in either a resting-state or a task-based paradigm. Compared to resting-state…

Image and Video Processing · Electrical Eng. & Systems 2025-02-18 Jiyao Wang , Nicha C. Dvornek , Peiyu Duan , Lawrence H. Staib , James S. Duncan

Functional magnetic resonance imaging (fMRI) is a powerful tool for investigating human brain function. However, the high cost of data acquisition and the inherent subjectivity of psychiatric rating scales often lead to datasets with small…

Machine Learning · Computer Science 2026-05-29 Jiyao Wang , Peiyu Duan , Nicha C. Dvornek , Lawrence H. Staib , Denis Sukhodolsky , Pamela Ventola , James S. Duncan

Many fMRI analyses examine functional connectivity, or statistical dependencies among remote brain regions. Yet popular methods for studying whole-brain functional connectivity often yield results that are difficult to interpret. Factor…

Methodology · Statistics 2024-09-24 Kyle Stanley , Nicole Lazar , Matthew Reimherr

Dynamic functional connectivity (DFC) analysis involves measuring correlated neural activity over time across multiple brain regions. Significant regional correlations among neural signals, such as those obtained from resting-state…

Understanding the neural mechanisms underlying the transitions between different states of consciousness is a fundamental challenge in neuroscience. Thus, we investigate the underlying drivers of changes during the resting-state dynamics of…

Neurons and Cognition · Quantitative Biology 2024-07-10 Joseph Bodenheimer , Paul Bogdan , Sérgio Pequito , Arian Ashourvan

Lesion detection in brain Magnetic Resonance Images (MRI) remains a challenging task. State-of-the-art approaches are mostly based on supervised learning making use of large annotated datasets. Human beings, on the other hand, even…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Xiaoran Chen , Ender Konukoglu

Functional connectomes capture brain interactions via synchronized fluctuations in the functional magnetic resonance imaging signal. If measured during rest, they map the intrinsic functional architecture of the brain. With task-driven…

Neurons and Cognition · Quantitative Biology 2013-04-16 Gaël Varoquaux , R. C. Craddock

This paper describes an approach of using dynamic Structural Equation Modeling (SEM) analysis to estimate the connectivity networks from resting-state fMRI data measured by a multiband EPI sequence. Two structural equation models were…

Neurons and Cognition · Quantitative Biology 2017-04-03 Jiancheng Zhuang

The human brain can be conceptualized as a dynamical system. Utilizing resting state fMRI time series imaging, we can study the underlying dynamics at ear-marked Regions of Interest (ROIs) to understand structure or lack thereof. This…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Ninad Aithal , Chakka Sai Pradeep , Neelam Sinha

We propose a method for estimating more reproducible functional networks that are more strongly associated with dynamic task activity by using recurrent neural networks with long short term memory (LSTMs). The LSTM model is trained in an…

Quantitative Methods · Quantitative Biology 2021-05-07 Nicha C. Dvornek , Pamela Ventola , James S. Duncan
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