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Stereotactic radiosurgery is a minimally-invasive treatment option for a large number of patients with intracranial tumors. As part of the therapy treatment, accurate delineation of brain tumors is of great importance. However,…

Brain metastases occur frequently in patients with metastatic cancer. Early and accurate detection of brain metastases is very essential for treatment planning and prognosis in radiation therapy. To improve brain metastasis detection…

Detecting and segmenting brain metastases is a tedious and time-consuming task for many radiologists, particularly with the growing use of multi-sequence 3D imaging. This study demonstrates automated detection and segmentation of brain…

Image and Video Processing · Electrical Eng. & Systems 2019-12-30 Endre Grøvik , Darvin Yi , Michael Iv , Elisabeth Tong , Daniel L. Rubin , Greg Zaharchuk

Brain metastases are a complication of primary cancer, representing the most common type of brain tumor in adults. The management of multiple brain metastases represents a clinical challenge worldwide in finding the optimal treatment for…

Image and Video Processing · Electrical Eng. & Systems 2024-03-28 Ana Sofia Santos , Matheus Silva , Crystian Saraiva , José Soares , Victor Alves

Brain metastases (BMs) are the most frequently occurring brain tumors. The treatment of patients having multiple BMs with stereo tactic radiosurgery necessitates accurate localization of the metastases. Neural networks can assist in this…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Ayhan Can Erdur , Daniel Scholz , Josef A. Buchner , Stephanie E. Combs , Daniel Rueckert , Jan C. Peeken

Background: Manual delineation of target volumes in head and neck cancer (HNC) remains a significant bottleneck in radiotherapy planning, characterized by high inter-observer variability and time consumption. This study evaluates the…

Background: Differentiating radiation necrosis (RN) from tumor progression after stereotactic radiosurgery (SRS) remains a critical challenge in brain metastases. While histopathology represents the gold standard, its invasiveness limits…

Resection and whole brain radiotherapy (WBRT) are the standards of care for the treatment of patients with brain metastases (BM) but are often associated with cognitive side effects. Stereotactic radiosurgery (SRS) involves a more targeted…

Stereotactic radiotherapy (SRT) is one of the most important treatment for patients with brain metastases (BM). Conventionally, following SRT patients are monitored by serial imaging and receive salvage treatments in case of significant…

Computer Vision and Pattern Recognition · Computer Science 2023-02-20 Philipp Sommer , Yixing Huang , Christoph Bert , Andreas Maier , Manuel Schmidt , Arnd Dörfler , Rainer Fietkau , Florian Putz

This study's objective was to segment spinal metastases in diagnostic MR images using a deep learning-based approach. Segmentation of such lesions can present a pivotal step towards enhanced therapy planning and validation, as well as…

Image and Video Processing · Electrical Eng. & Systems 2020-01-29 Georg Hille , Johannes Steffen , Max Dünnwald , Mathias Becker , Sylvia Saalfeld , Klaus Tönnies

Multimodal brain tumor segmentation challenge (BraTS) brings together researchers to improve automated methods for 3D MRI brain tumor segmentation. Tumor segmentation is one of the fundamental vision tasks necessary for diagnosis and…

Image and Video Processing · Electrical Eng. & Systems 2020-01-08 Andriy Myronenko , Ali Hatamizadeh

Brain metastasis segmentation poses a significant challenge in medical imaging due to the complex presentation and variability in size and location of metastases. In this study, we first investigate the impact of different imaging…

Image and Video Processing · Electrical Eng. & Systems 2024-07-22 Yousef Sadegheih , Dorit Merhof

Deep learning methods are actively used for brain lesion segmentation. One of the most popular models is DeepMedic, which was developed for segmentation of relatively large lesions like glioma and ischemic stroke. In our work, we consider…

Computer Vision and Pattern Recognition · Computer Science 2018-08-02 Egor Krivov , Valery Kostjuchenko , Alexandra Dalechina , Boris Shirokikh , Gleb karchuk , Alexander Denisenko , Andrey Golanov , Mikhail Belyaev

Brain Metastases (BM) are a large contributor to mortality of patients with cancer. They are treated with Stereotactic Radiosurgery (SRS) and monitored with Magnetic Resonance Imaging (MRI) at regular follow-up intervals according to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Lorenz Achim Kuhn , Daniel Abler , Jonas Richiardi , Andreas F. Hottinger , Luis Schiappacasse , Vincent Dunet , Adrien Depeursinge , Vincent Andrearczyk

The magnetic resonance (MR) analysis of brain tumors is widely used for diagnosis and examination of tumor subregions. The overlapping area among the intensity distribution of healthy, enhancing, non-enhancing, and edema regions makes the…

Image and Video Processing · Electrical Eng. & Systems 2020-06-01 Mohammad Hamghalam , Baiying Lei , Tianfu Wang

Automatic segmentation of brain tumors is an essential but challenging step for extracting quantitative imaging biomarkers for accurate tumor detection, diagnosis, prognosis, treatment planning and assessment. Multimodal Brain Tumor…

Image and Video Processing · Electrical Eng. & Systems 2020-11-30 Yading Yuan

Brain cancer can be very fatal, but chances of survival increase through early detection and treatment. Doctors use Magnetic Resonance Imaging (MRI) to detect and locate tumors in the brain, and very carefully analyze scans to segment brain…

Computer Vision and Pattern Recognition · Computer Science 2018-11-08 Ryan Sherman

Background: A growing number of cancer patients with brain metastases can benefit from stereotactic radiosurgery (SRS) thanks to recent advances in systemic therapies. With an increasing patient load, single-isocenter treatments on widely…

Medical Physics · Physics 2025-10-08 Johan Sundström , Anton Finnson , Elin Hynning , Geert De Kerf , Albin Fredriksson

Semantic segmentation of medical images with deep learning models is rapidly developed. In this study, we benchmarked state-of-the-art deep learning segmentation algorithms on our clinical stereotactic radiosurgery dataset, demonstrating…

Image and Video Processing · Electrical Eng. & Systems 2020-07-24 Siang-Ruei Wu , Hao-Yun Chang , Florence T Su , Heng-Chun Liao , Wanju Tseng , Chun-Chih Liao , Feipei Lai , Feng-Ming Hsu , Furen Xiao

Despite continuous advancements in cancer treatment, brain metastatic disease remains a significant complication of primary cancer and is associated with an unfavorable prognosis. One approach for improving diagnosis, management, and…

Other Quantitative Biology · Quantitative Biology 2025-07-11 Nazanin Maleki , Raisa Amiruddin , Ahmed W. Moawad , Nikolay Yordanov , Athanasios Gkampenis , Pascal Fehringer , Fabian Umeh , Crystal Chukwurah , Fatima Memon , Bojan Petrovic , Justin Cramer , Mark Krycia , Elizabeth B. Shrickel , Ichiro Ikuta , Gerard Thompson , Lorenna Vidal , Vilma Kosovic , Adam E. Goldman-Yassen , Virginia Hill , Tiffany So , Sedra Mhana , Albara Alotaibi , Nathan Page , Prisha Bhatia , Melisa S. Guelen , Yasaman Sharifi , Marko Jakovljevic , Salma Abosabie , Sara Abosabie , Mohanad Ghonim , Mohamed Ghonim , Amirreza Manteghinejad , Anastasia Janas , Kiril Krantchev , Maruf Adewole , Jake Albrecht , Udunna Anazodo , Sanjay Aneja , Syed Muhammad Anwar , Timothy Bergquist , Veronica Chiang , Verena Chung , Gian Marco Conte , Farouk Dako , James Eddy , Ivan Ezhov , Nastaran Khalili , Keyvan Farahani , Juan Eugenio Iglesias , Zhifan Jiang , Elaine Johanson , Anahita Fathi Kazerooni , Florian Kofler , Dominic LaBella , Koen Van Leemput , Hongwei Bran Li , Marius George Linguraru , Xinyang Liu , Zeke Meier , Bjoern H Menze , Harrison Moy , Klara Osenberg , Marie Piraud , Zachary Reitman , Russell Takeshi Shinohara , Chunhao Wang , Benedikt Wiestler , Walter Wiggins , Umber Shafique , Klara Willms , Arman Avesta , Khaled Bousabarah , Satrajit Chakrabarty , Nicolo Gennaro , Wolfgang Holler , Manpreet Kaur , Pamela LaMontagne , MingDe Lin , Jan Lost , Daniel S. Marcus , Ryan Maresca , Sarah Merkaj , Gabriel Cassinelli Pedersen , Marc von Reppert , Aristeidis Sotiras , Oleg Teytelboym , Niklas Tillmans , Malte Westerhoff , Ayda Youssef , Devon Godfrey , Scott Floyd , Andreas Rauschecker , Javier Villanueva-Meyer , Irada Pflüger , Jaeyoung Cho , Martin Bendszus , Gianluca Brugnara , Gloria J. Guzman Perez-Carillo , Derek R. Johnson , Anthony Kam , Benjamin Yin Ming Kwan , Lillian Lai , Neil U. Lall , Satya Narayana Patro , Lei Wu , Anu Bansal , Frederik Barkhof , Cristina Besada , Sammy Chu , Jason Druzgal , Alexandru Dusoi , Luciano Farage , Fabricio Feltrin , Amy Fong , Steve H. Fung , R. Ian Gray , Michael Iv , Alida A. Postma , Amit Mahajan , David Joyner , Chase Krumpelman , Laurent Letourneau-Guillon , Christie M. Lincoln , Mate E. Maros , Elka Miller , Fanny Morón , Esther A. Nimchinsky , Ozkan Ozsarlak , Uresh Patel , Saurabh Rohatgi , Atin Saha , Anousheh Sayah , Eric D. Schwartz , Robert Shih , Mark S. Shiroishi , Juan E. Small , Manoj Tanwar , Jewels Valerie , Brent D. Weinberg , Matthew L. White , Robert Young , Vahe M. Zohrabian , Aynur Azizova , Melanie Maria Theresa Brüßeler , Abdullah Okar , Luca Pasquini , Yasaman Sharifi , Gagandeep Singh , Nico Sollmann , Theodora Soumala , Mahsa Taherzadeh , Philipp Vollmuth , Martha Foltyn-Dumitru , Ajay Malhotra , Francesco Dellepiane , Víctor M. Pérez-García , Hesham Elhalawani , Maria Correia de Verdier , Sanaria Al Rubaiey , Rui Duarte Armindo , Kholod Ashraf , Moamen M. Asla , Mohamed Badawy , Jeroen Bisschop , Nima Broomand Lomer , Jan Bukatz , Jim Chen , Petra Cimflova , Felix Corr , Alexis Crawley , Lisa Deptula , Tasneem Elakhdar , Islam H. Shawali , Shahriar Faghani , Alexandra Frick , Vaibhav Gulati , Muhammad Ammar Haider , Fátima Hierro , Rasmus Holmboe Dahl , Sarah Maria Jacobs , Kuang-chun Jim Hsieh , Sedat G. Kandemirli , Katharina Kersting , Laura Kida , Sofia Kollia , Ioannis Koukoulithras , Xiao Li , Ahmed Abouelatta , Aya Mansour , Ruxandra-Catrinel Maria-Zamfirescu , Marcela Marsiglia , Yohana Sarahi Mateo-Camacho , Mark McArthur , Olivia McDonnel , Maire McHugh , Mana Moassefi , Samah Mostafa Morsi , Alexander Munteanu , Khanak K. Nandolia , Syed Raza Naqvi , Yalda Nikanpour , Mostafa Alnoury , Abdullah Mohamed Aly Nouh , Francesca Pappafava , Markand D. Patel , Samantha Petrucci , Eric Rawie , Scott Raymond , Borna Roohani , Sadeq Sabouhi , Laura M. Sanchez Garcia , Zoe Shaked , Pokhraj P. Suthar , Talissa Altes , Edvin Isufi , Yaseen Dhemesh , Jaime Gass , Jonathan Thacker , Abdul Rahman Tarabishy , Benjamin Turner , Sebastiano Vacca , George K. Vilanilam , Daniel Warren , David Weiss , Fikadu Worede , Sara Yousry , Wondwossen Lerebo , Alejandro Aristizabal , Alexandros Karargyris , Hasan Kassem , Sarthak Pati , Micah Sheller , Katherine E. Link , Evan Calabrese , Nourel Hoda Tahon , Ayman Nada , Jeffrey D. Rudie , Janet Reid , Kassa Darge , Aly H. Abayazeed , Philipp Lohmann , Yuri S. Velichko , Spyridon Bakas , Mariam Aboian
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