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In digital pathology, both detection and classification of cells are important for automatic diagnostic and prognostic tasks. Classifying cells into subtypes, such as tumor cells, lymphocytes or stromal cells is particularly challenging.…

Computer Vision and Pattern Recognition · Computer Science 2022-06-07 Shahira Abousamra , David Belinsky , John Van Arnam , Felicia Allard , Eric Yee , Rajarsi Gupta , Tahsin Kurc , Dimitris Samaras , Joel Saltz , Chao Chen

The task of spatial clustering of transcriptomics data is of paramount importance. It enables the classification of tissue samples into diverse subpopulations of cells, which, in turn, facilitates the analysis of the biological functions of…

Machine Learning · Computer Science 2025-07-29 Mehrad Soltani , Luis Rueda

In this paper, we examine the strength of deep learning technique for diagnosing lung cancer on medical image analysis problem. Convolutional neural networks (CNNs) models become popular among the pattern recognition and computer vision…

Computer Vision and Pattern Recognition · Computer Science 2018-04-24 Mehdi Fatan Serj , Bahram Lavi , Gabriela Hoff , Domenec Puig Valls

In recent years, advances in the development of whole-slide images have laid a foundation for the utilization of digital images in pathology. With the assistance of computer images analysis that automatically identifies tissue or cell…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Jun Wang , Qianying Liu , Haotian Xie , Zhaogang Yang , Hefeng Zhou

Traditional breast cancer image classification methods require manual extraction of features from medical images, which not only require professional medical knowledge, but also have problems such as time-consuming and labor-intensive and…

Image and Video Processing · Electrical Eng. & Systems 2021-04-26 Mengfan Li

Breast cancer is one of the most serious types of cancer that can occur in women. The automatic diagnosis of breast cancer by analyzing histological images (HIs) is important for patients and their prognosis. The classification of HIs…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Hayder A. Khikani , Naira Elazab , Ahmed Elgarayhi , Mohammed Elmogy , Mohammed Sallah

Histopathological analysis of Whole Slide Images (WSIs) has seen a surge in the utilization of deep learning methods, particularly Convolutional Neural Networks (CNNs). However, CNNs often fall short in capturing the intricate spatial…

Computer Vision and Pattern Recognition · Computer Science 2024-06-24 Siemen Brussee , Giorgio Buzzanca , Anne M. R. Schrader , Jesper Kers

Fine-grained classification of cervical cells into different abnormality levels is of great clinical importance but remains very challenging. Contrary to traditional classification methods that rely on hand-crafted or engineered features,…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Haoming Lin , Yuyang Hu , Siping Chen , Jianhua Yao , Ling Zhang

Breast cancer is the most common cancer in women. Classification of cancer/non-cancer patients with clinical records requires high sensitivity and specificity for an acceptable diagnosis test. The state-of-the-art classification model -…

Computer Vision and Pattern Recognition · Computer Science 2024-02-12 Anuraganand Sharma , Dinesh Kumar

Convolutional neural networks (CNNs) are a standard tool for computer vision tasks such as image classification. However, typical model architectures may result in the loss of topological information. In specific domains such as…

Image and Video Processing · Electrical Eng. & Systems 2026-03-05 Shrunal Pothagoni , Benjamin Schweinhart

In this paper, we present different architectures of Convolutional Neural Networks (CNN) to analyze and classify the brain tumors into benign and malignant types using the Magnetic Resonance Imaging (MRI) technique. Different CNN…

Image and Video Processing · Electrical Eng. & Systems 2023-07-17 Aupam Hamran , Marzieh Vaeztourshizi , Amirhossein Esmaili , Massoud Pedram

In recent years, deep learning based methods have shown success in essential medical image analysis tasks such as segmentation. Post-processing and refining the results of segmentation is a common practice to decrease the misclassifications…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Ufuk Demir , Atahan Ozer , Yusuf H. Sahin , Gozde Unal

While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowledge, and are often considered as a "black-box." The lack of…

Computer Vision and Pattern Recognition · Computer Science 2018-06-05 Shiwen Shen , Simon X. Han , Denise R. Aberle , Alex A. T. Bui , Willliam Hsu

Early detection of cancerous tissue is crucial for long-term patient survival. In the head and neck region, a typical diagnostic procedure is an endoscopic intervention where a medical expert manually assesses tissue using RGB camera…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Marcel Bengs , Nils Gessert , Wiebke Laffers , Dennis Eggert , Stephan Westermann , Nina A. Mueller , Andreas O. H. Gerstner , Christian Betz , Alexander Schlaefer

The objective of image manipulation detection is to identify and locate the manipulated regions in the images. Recent approaches mostly adopt the sophisticated Convolutional Neural Networks (CNNs) to capture the tampering artifacts left in…

Computer Vision and Pattern Recognition · Computer Science 2022-01-19 Wenyan Pan , Zhili Zhou , Miaogen Ling , Xin Geng , Q. M. Jonathan Wu

Segmentation of histological images is one of the most crucial tasks for many biomedical analyses including quantification of certain tissue type. However, challenges are posed by high variability and complexity of structural features in…

Computer Vision and Pattern Recognition · Computer Science 2020-07-30 Xiaohang Fu , Tong Liu , Zhaohan Xiong , Bruce H. Smaill , Martin K. Stiles , Jichao Zhao

Early detection of cancer plays a key role in improving survival rates, but identifying reliable biomarkers from RNA-seq data is still a major challenge. The data are high-dimensional, and conventional statistical methods often fail to…

Machine Learning · Computer Science 2025-12-09 Shreyas Shende , Varsha Narayanan , Vishal Fenn , Yiran Huang , Dincer Goksuluk , Gaurav Choudhary , Melih Agraz , Mengjia Xu

We propose a novel computational framework leveraging hypergraph theory to analyse cancer stem cell markers (CSCMs) across multiple organs. Hypergraphs provide a robust representation of CSCM co-expression patterns, capturing their complex…

Biological Physics · Physics 2025-08-01 David H. Margarit , Gustavo Paccosi , Marcela V. Reale , Lilia M. Romanelli

Accurate diagnosis of breast cancer in histopathology images is challenging due to the heterogeneity of cancer cell growth as well as of a variety of benign breast tissue proliferative lesions. In this paper, we propose a practical and…

Computer Vision and Pattern Recognition · Computer Science 2020-05-06 Xingyu Li , Marko Radulovic , Ksenija Kanjer , Konstantinos N. Plataniotis

Predicting outcomes, such as survival or metastasis for individual cancer patients is a crucial component of precision oncology. Machine learning (ML) offers a promising way to exploit rich multi-modal data, including clinical information…

Machine Learning · Computer Science 2021-06-04 Michal Kazmierski , Benjamin Haibe-Kains
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