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Most of the current state-of-the-art methods for tumor segmentation are based on machine learning models trained on manually segmented images. This type of training data is particularly costly, as manual delineation of tumors is not only…
Accurate segmentation of infant brain MRI is critical for studying early neurodevelopment and diagnosing neurological disorders. Yet, it remains a fundamental challenge due to continuously evolving anatomy of the subjects, motion artifacts,…
Transfer learning with pre-trained neural networks is a common strategy for training classifiers in medical image analysis. Without proper channel selections, this often results in unnecessarily large models that hinder deployment and…
Graph neural networks (GNNs), which learn the node representations by recursively aggregating information from its neighbors, have become a predominant computational tool in many domains. To handle large-scale graphs, most of the existing…
Recent advances in deep learning for medical image segmentation demonstrate expert-level accuracy. However, in clinically realistic environments, such methods have marginal performance due to differences in image domains, including…
Despite their impressive performance, Deep Neural Networks (DNNs) typically underperform Gradient Boosting Trees (GBTs) on many tabular-dataset learning tasks. We propose that applying a different regularization coefficient to each weight…
Transfer learning refers to machine learning techniques that focus on acquiring knowledge from related tasks to improve generalization in the tasks of interest. In MRI, transfer learning is important for developing strategies that address…
Generalization of neural networks is crucial for deploying them safely in the real world. Common training strategies to improve generalization involve the use of data augmentations, ensembling and model averaging. In this work, we first…
Domain shift is a significant problem in histopathology. There can be large differences in data characteristics of whole-slide images between medical centers and scanners, making generalization of deep learning to unseen data difficult. To…
Supervised Fine-Tuning (SFT) on domain-specific datasets is a common approach to adapt Large Language Models (LLMs) to specialized tasks but is often believed to degrade their general capabilities. In this work, we revisit this trade-off…
Deep learning-based models in medical imaging often struggle to generalize effectively to new scans due to data heterogeneity arising from differences in hardware, acquisition parameters, population, and artifacts. This limitation presents…
Self-supervised learning (SSL) has advanced medical image analysis be enabling learning form large unlabelled data. However, in brain magnetic resonance imaging (MRI), most 3D models remain specialized for either segmentation of…
White matter (WM) tract segmentation is a crucial step for brain connectivity studies. It is performed on diffusion magnetic resonance imaging (dMRI), and deep neural networks (DNNs) have achieved promising segmentation accuracy. Existing…
Many clinical and research studies of the human brain require an accurate structural MRI segmentation. While traditional atlas-based methods can be applied to volumes from any acquisition site, recent deep learning algorithms ensure very…
Background: Synthetic computed tomography (sCT) has been proposed and increasingly clinically adopted to enable magnetic resonance imaging (MRI)-based radiotherapy. Deep learning (DL) has recently demonstrated the ability to generate…
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition whose rising prevalence places increasing demands on a lengthy diagnostic process. Machine learning (ML) has shown promise in automating ASD diagnosis, but most…
Medical image classification plays an increasingly vital role in identifying various diseases by classifying medical images, such as X-rays, MRIs and CT scans, into different categories based on their features. In recent years, deep…
Contrast-enhanced Computed Tomography (CT) is important for diagnosis and treatment planning for various medical conditions. Deep learning (DL) based segmentation models may enable automated medical image analysis for detecting and…
Differential diagnosis of dementia is challenging due to overlapping symptoms, with structural magnetic resonance imaging (MRI) being the primary method for diagnosis. Despite the clinical value of computer-aided differential diagnosis,…
Multi-Task Learning (MTL) is a framework, where multiple related tasks are learned jointly and benefit from a shared representation space, or parameter transfer. To provide sufficient learning support, modern MTL uses annotated data with…