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Early detection of brain metastases (BM) is one of the determining factors for the successful treatment of patients with cancer; however, the accurate detection of small BM lesions (< 15mm) remains a challenging task. We previously…

Image and Video Processing · Electrical Eng. & Systems 2021-05-31 Engin Dikici , Xuan V. Nguyen , Matthew Bigelow , Luciano M. Prevedello

The detection of brain metastases (BM) in their early stages could have a positive impact on the outcome of cancer patients. We previously developed a framework for detecting small BM (with diameters of less than 15mm) in T1-weighted…

Image and Video Processing · Electrical Eng. & Systems 2021-11-22 Engin Dikici , Xuan V. Nguyen , Matthew Bigelow , John. L. Ryu , Luciano M. Prevedello

Resection and whole brain radiotherapy (WBRT) are the standards of care for the treatment of patients with brain metastases (BM) but are often associated with cognitive side effects. Stereotactic radiosurgery (SRS) involves a more targeted…

Brain metastases (BMs) are the most frequently occurring brain tumors. The treatment of patients having multiple BMs with stereo tactic radiosurgery necessitates accurate localization of the metastases. Neural networks can assist in this…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Ayhan Can Erdur , Daniel Scholz , Josef A. Buchner , Stephanie E. Combs , Daniel Rueckert , Jan C. Peeken

Detecting and segmenting brain metastases is a tedious and time-consuming task for many radiologists, particularly with the growing use of multi-sequence 3D imaging. This study demonstrates automated detection and segmentation of brain…

Image and Video Processing · Electrical Eng. & Systems 2019-12-30 Endre Grøvik , Darvin Yi , Michael Iv , Elisabeth Tong , Daniel L. Rubin , Greg Zaharchuk

Brain metastasis segmentation poses a significant challenge in medical imaging due to the complex presentation and variability in size and location of metastases. In this study, we first investigate the impact of different imaging…

Image and Video Processing · Electrical Eng. & Systems 2024-07-22 Yousef Sadegheih , Dorit Merhof

Brain metastases occur frequently in patients with metastatic cancer. Early and accurate detection of brain metastases is very essential for treatment planning and prognosis in radiation therapy. To improve brain metastasis detection…

Melanoma brain metastases (MBM) are common and spatially heterogeneous lesions, complicating cohort-level analyses due to anatomical variability and differing MRI protocols. We propose a fully differentiable, deep-learning-based deformable…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Nanna E. Wielenberg , Ilinca Popp , Oliver Blanck , Lucas Zander , Jan C. Peeken , Stephanie E. Combs , Anca-Ligia Grosu , Dimos Baltas , Tobias Fechter

Brain metastases are a common complication of systemic cancer, affecting over 20% of patients with primary malignancies. Longitudinal magnetic resonance imaging (MRI) is essential for diagnosing patients, tracking disease progression,…

Glioblastoma, the most aggressive primary brain tumor, poses a severe clinical challenge due to its diffuse microscopic infiltration, which remains largely undetected on standard MRI. As a result, current radiotherapy planning employs a…

A medical AI system's generalizability describes the continuity of its performance acquired from varying geographic, historical, and methodologic settings. Previous literature on this topic has mostly focused on "how" to achieve high…

Image and Video Processing · Electrical Eng. & Systems 2022-12-19 Engin Dikici , Xuan Nguyen , Noah Takacs , Luciano M. Prevedello

The translation of AI-generated brain metastases (BM) segmentation into clinical practice relies heavily on diverse, high-quality annotated medical imaging datasets. The BraTS-METS 2023 challenge has gained momentum for testing and…

Other Quantitative Biology · Quantitative Biology 2024-12-10 Ahmed W. Moawad , Anastasia Janas , Ujjwal Baid , Divya Ramakrishnan , Rachit Saluja , Nader Ashraf , Nazanin Maleki , Leon Jekel , Nikolay Yordanov , Pascal Fehringer , Athanasios Gkampenis , Raisa Amiruddin , Amirreza Manteghinejad , Maruf Adewole , Jake Albrecht , Udunna Anazodo , Sanjay Aneja , Syed Muhammad Anwar , Timothy Bergquist , Veronica Chiang , Verena Chung , Gian Marco Conte , Farouk Dako , James Eddy , Ivan Ezhov , Nastaran Khalili , Keyvan Farahani , Juan Eugenio Iglesias , Zhifan Jiang , Elaine Johanson , Anahita Fathi Kazerooni , Florian Kofler , Kiril Krantchev , Dominic LaBella , Koen Van Leemput , Hongwei Bran Li , Marius George Linguraru , Xinyang Liu , Zeke Meier , Bjoern H Menze , Harrison Moy , Klara Osenberg , Marie Piraud , Zachary Reitman , Russell Takeshi Shinohara , Chunhao Wang , Benedikt Wiestler , Walter Wiggins , Umber Shafique , Klara Willms , Arman Avesta , Khaled Bousabarah , Satrajit Chakrabarty , Nicolo Gennaro , Wolfgang Holler , Manpreet Kaur , Pamela LaMontagne , MingDe Lin , Jan Lost , Daniel S. Marcus , Ryan Maresca , Sarah Merkaj , Gabriel Cassinelli Pedersen , Marc von Reppert , Aristeidis Sotiras , Oleg Teytelboym , Niklas Tillmans , Malte Westerhoff , Ayda Youssef , Devon Godfrey , Scott Floyd , Andreas Rauschecker , Javier Villanueva-Meyer , Irada Pfluger , Jaeyoung Cho , Martin Bendszus , Gianluca Brugnara , Justin Cramer , Gloria J. Guzman Perez-Carillo , Derek R. Johnson , Anthony Kam , Benjamin Yin Ming Kwan , Lillian Lai , Neil U. Lall , Fatima Memon , Mark Krycia , Satya Narayana Patro , Bojan Petrovic , Tiffany Y. So , Gerard Thompson , Lei Wu , E. Brooke Schrickel , Anu Bansal , Frederik Barkhof , Cristina Besada , Sammy Chu , Jason Druzgal , Alexandru Dusoi , Luciano Farage , Fabricio Feltrin , Amy Fong , Steve H. Fung , R. Ian Gray , Ichiro Ikuta , Michael Iv , Alida A. Postma , Amit Mahajan , David Joyner , Chase Krumpelman , Laurent Letourneau-Guillon , Christie M. Lincoln , Mate E. Maros , Elka Miller , Fanny Moron , Esther A. Nimchinsky , Ozkan Ozsarlak , Uresh Patel , Saurabh Rohatgi , Atin Saha , Anousheh Sayah , Eric D. Schwartz , Robert Shih , Mark S. Shiroishi , Juan E. Small , Manoj Tanwar , Jewels Valerie , Brent D. Weinberg , Matthew L. White , Robert Young , Vahe M. Zohrabian , Aynur Azizova , Melanie Maria Theresa Bruseler , Mohanad Ghonim , Mohamed Ghonim , Abdullah Okar , Luca Pasquini , Yasaman Sharifi , Gagandeep Singh , Nico Sollmann , Theodora Soumala , Mahsa Taherzadeh , Philipp Vollmuth , Martha Foltyn-Dumitru , Ajay Malhotra , Aly H. Abayazeed , Francesco Dellepiane , Philipp Lohmann , Victor M. Perez-Garcia , Hesham Elhalawani , Maria Correia de Verdier , Sanaria Al-Rubaiey , Rui Duarte Armindo , Kholod Ashraf , Moamen M. Asla , Mohamed Badawy , Jeroen Bisschop , Nima Broomand Lomer , Jan Bukatz , Jim Chen , Petra Cimflova , Felix Corr , Alexis Crawley , Lisa Deptula , Tasneem Elakhdar , Islam H. Shawali , Shahriar Faghani , Alexandra Frick , Vaibhav Gulati , Muhammad Ammar Haider , Fatima Hierro , Rasmus Holmboe Dahl , Sarah Maria Jacobs , Kuang-chun Jim Hsieh , Sedat G. Kandemirli , Katharina Kersting , Laura Kida , Sofia Kollia , Ioannis Koukoulithras , Xiao Li , Ahmed Abouelatta , Aya Mansour , Ruxandra-Catrinel Maria-Zamfirescu , Marcela Marsiglia , Yohana Sarahi Mateo-Camacho , Mark McArthur , Olivia McDonnell , Maire McHugh , Mana Moassefi , Samah Mostafa Morsi , Alexander Munteanu , Khanak K. Nandolia , Syed Raza Naqvi , Yalda Nikanpour , Mostafa Alnoury , Abdullah Mohamed Aly Nouh , Francesca Pappafava , Markand D. Patel , Samantha Petrucci , Eric Rawie , Scott Raymond , Borna Roohani , Sadeq Sabouhi , Laura M. Sanchez-Garcia , Zoe Shaked , Pokhraj P. Suthar , Talissa Altes , Edvin Isufi , Yaseen Dhemesh , Jaime Gass , Jonathan Thacker , Abdul Rahman Tarabishy , Benjamin Turner , Sebastiano Vacca , George K. Vilanilam , Daniel Warren , David Weiss , Fikadu Worede , Sara Yousry , Wondwossen Lerebo , Alejandro Aristizabal , Alexandros Karargyris , Hasan Kassem , Sarthak Pati , Micah Sheller , Katherine E. Link , Evan Calabrese , Nourel hoda Tahon , Ayman Nada , Yuri S. Velichko , Spyridon Bakas , Jeffrey D. Rudie , Mariam Aboian

Tumor segmentation from multi-modal brain MRI images is a challenging task due to the limited samples, high variance in shapes and uneven distribution of tumor morphology. The performance of automated medical image segmentation has been…

Image and Video Processing · Electrical Eng. & Systems 2024-02-13 Tianyi Ren , Ethan Honey , Harshitha Rebala , Abhishek Sharma , Agamdeep Chopra , Mehmet Kurt

Brain tumor detection can make the difference between life and death. Recently, deep learning-based brain tumor detection techniques have gained attention due to their higher performance. However, obtaining the expected performance of such…

Image and Video Processing · Electrical Eng. & Systems 2022-02-22 Wessam M. Salama , Ahmed Shokry

Accurate and automatic segmentation of brain tumors in multi-parametric magnetic resonance imaging (mpMRI) is essential for quantitative measurements, which play an increasingly important role in clinical diagnosis and prognosis. The…

Previous studies on computer aided detection/diagnosis (CAD) in 4D breast magnetic resonance imaging (MRI) regard lesion detection, segmentation and characterization as separate tasks, and typically require users to manually select 2D MRI…

Image and Video Processing · Electrical Eng. & Systems 2020-07-08 Hang Min , Darryl McClymont , Shekhar S. Chandra , Stuart Crozier , Andrew P. Bradley

Brain Metastases (BM) are a large contributor to mortality of patients with cancer. They are treated with Stereotactic Radiosurgery (SRS) and monitored with Magnetic Resonance Imaging (MRI) at regular follow-up intervals according to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Lorenz Achim Kuhn , Daniel Abler , Jonas Richiardi , Andreas F. Hottinger , Luis Schiappacasse , Vincent Dunet , Adrien Depeursinge , Vincent Andrearczyk

Background: Deep learning has demonstrated significant potential for automated brain metastases (BM) segmentation; however, models trained at a singular institution often exhibit suboptimal performance at various sites due to disparities in…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Yuchen Yang , Shuangyang Zhong , Haijun Yu , Langcuomu Suo , Hongbin Han , Florian Putz , Yixing Huang

Brain metastases are a common diagnosis that affects between 20% and 40% of cancer patients. Subsequent to radiation therapy, patients with brain metastases undergo follow-up sessions during which the response to treatment is monitored. In…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Margarida Fernandes , José Soares , Matheus Silva , Crystian Saraiva , Victor Alves

Objective: Brain metastases (BMs) are common in cancer patients and determining the primary tumor site is crucial for effective treatment. This study aims to predict the primary tumor site from BM MRI data using radiomic features and…

Machine Learning · Computer Science 2024-07-09 Hamidreza Sadeghsalehi
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