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Many motile biological cells navigate along concentration gradients of signaling molecules: This chemotaxis guides for instance sperm cells from marine invertebrates, which have to find egg cells in the ocean. While chemotaxis has been…

Biological Physics · Physics 2022-09-21 Steffen Lange , Benjamin M. Friedrich

Living cells are capable of interacting with their environments in a variety of ways, including cell signalling, adhesion, and directed motion. These behaviours are often mediated by receptor molecules embedded in the cell membrane, which…

Biological Physics · Physics 2023-10-17 Hannah Sleath , Bortolo Mognetti , Yuval Elani , Lorenzo Di Michele

We investigate the boundary between chemotaxis driven by spatial estimation of gradients and chemotaxis driven by temporal estimation. While it is well known that spatial chemotaxis becomes disadvantageous for small organisms at high noise…

Neural and Evolutionary Computing · Computer Science 2024-06-18 Albert Alonso , Julius B. Kirkegaard

Many motile microorganisms react to environmental light cues with a variety of motility responses guiding cells towards better conditions for survival and growth. The use of spatial light modulators could help to elucidate the mechanisms of…

The Keller-Segel system has been widely proposed as a model for bacterial waves driven by chemotactic processes. Current experiments on {\em E. coli} have shown precise structure of traveling pulses. We present here an alternative…

Adaptive response to a varying environment is a common feature of biological organisms. Reproducing such features in electronic systems and circuits is of great importance for a variety of applications. Here, we consider memory models…

Cell Behavior · Quantitative Biology 2013-10-29 Fabio Lorenzo Traversa , Yuriy V. Pershin , Massimiliano Di Ventra

Understanding how the physical properties of a fluid influence bacterial behavior is essential for explaining how microorganisms interact with their environment and with animal hosts. Here, we examine how changes in fluid viscosity and…

Soft Condensed Matter · Physics 2026-02-05 Chunhe Li , Zixiang Lin , Hongyi Bian , Anqi Li , Honyi Xin , Zijie Qu

Conjugation accelerates bacterial evolution by enabling bacteria to acquire genes horizontally from their neighbors. Plasmid donors must physically encounter and connect with recipients to allow plasmid transfer, and different environments…

Biological Physics · Physics 2025-08-08 Matti Zbinden , Jana S. Huisman , Natasha Blitvic , Roman Stocker , Jonasz Słomka

Experiments have recently shown the feasibility of utilising bacteria as micro-scale robotic devices, with special attention paid to the development of bacteria-driven micro-swimmers taking advantage of built-in actuation and sensing…

Soft Condensed Matter · Physics 2019-02-14 Christian Esparza Lopez , Albane Thery , Eric Lauga

Recent research has shown that motile cells can adapt their mode of propulsion to the mechanical properties of the environment in which they find themselves--crawling in some environments while swimming in others. The latter can involve…

Biological Physics · Physics 2018-05-24 Hao Wu , Marco Avila Ponce de Leon , Hans G. Othmer

The flagellated bacterium Escherichia coli is increasingly used experimentally as a self-propelled swimmer. To obtain meaningful, quantitative results that are comparable between different laboratories, reproducible protocols are needed to…

Bacteria seem masters of chemotaxis, yet recent work suggests otherwise. Henry Mattingly and colleagues (Nature Physics, 2026) argue that Escherichia coli uses only a small fraction of the sensory information available at its surface,…

Cell Behavior · Quantitative Biology 2026-01-16 Robert G. Endres

The chemotactic pathway allows bacteria to respond and adapt to environmental changes, by tuning the tumbling and running motions that are due to clockwise and counterclockwise rotations of their flagella. The pathway is tightly regulated…

Molecular Networks · Quantitative Biology 2009-10-09 Daniela Besozzi , Paolo Cazzaniga , Matteo Dugo , Dario Pescini , Giancarlo Mauri

Response time-delay is an ubiquitous phenomenon in biological systems. Here we use a simple stochastic population model with time-delayed switching-rate conversion to quantitatively study the biological influence of the response time-delay…

Populations and Evolution · Quantitative Biology 2009-04-14 Xiao chuan Xue , Jinhua Zhao , Fei Liu , Zhong-can Ou-Yang

We recently found that marine bacteria Vibrio alginolyticus execute a cyclic 3-step (run- reverse-flick) motility pattern that is distinctively different from the 2-step (run-tumble) pattern of Escherichia coli. How this novel swimming…

Cell Behavior · Quantitative Biology 2017-07-26 Tuba Altindal , Li Xie , Xiao-Lun Wu

Bacteria are able to respond to environmental signals by changing their rules of movement. When we take into account chemical signals in the environment, this behaviour is often called chemotaxis. At the individual-level, chemotaxis…

Analysis of PDEs · Mathematics 2007-05-23 Radek Erban , Hyung Ju Hwang

We explore how different types and uses of memory can aid spatial navigation in changing uncertain environments. In the simple foraging task we study, every day, our agent has to find its way from its home, through barriers, to food.…

Artificial Intelligence · Computer Science 2026-02-18 Omid Madani , J. Brian Burns , Reza Eghbali , Thomas L. Dean

Motivated by observations of the dynamics of {\it Myxococcus xanthus}, we present a self-interacting random walk model that describes the competition between chemokinesis and chemotaxis. Cells are constrained to move in one dimension, but…

Statistical Mechanics · Physics 2016-08-31 Maria R. D'Orsogna , Marc Suchard , Tom Chou

A large number of biological systems - from bacteria to sheep - can be described as ensembles of self-propelled agents (active particles) with a complex internal dynamic that controls the agent's behavior: resting, moving slow, moving fast,…

Biological Physics · Physics 2021-09-03 L. Gómez-Nava , T. Goudon , F. Peruani

The Keller-Segel model is a system of partial differential equations modelling chemotactic aggregation in cellular systems. This model has blowing up solutions for large enough initial conditions in dimensions d >= 2, but all the solutions…

Analysis of PDEs · Mathematics 2009-11-11 Carlos Escudero