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Simple expressions for the bending and the base-stacking energy of double-stranded semiflexible biopolymers (such as DNA and actin) are derived. The distribution of the folding angle between the two strands is obtained by solving a…

Soft Condensed Matter · Physics 2009-10-31 Zhou Haijun , Ou-Yang Zhong-can

We propose a mathematical model of DNA self-assembly using 2D tiles to form 3D nanostructures. This is the first work to combine studies in self-assembly and nanotechnology in 3D, just as Rothemund and Winfree did in the 2D case. Our model…

Computational Complexity · Computer Science 2007-05-23 Ming-Yang Kao , Vijay Ramachandran

Nanoparticle gels have attracted considerable attention due to their highly tunable properties. One strategy for producing nanoparticle gels involves using strong local attractions between polymeric molecules, such as DNA hybridization or…

We introduce an analytical method to generate the pathway of a closed protein-bound DNA minicircle. This is a general method which can be used to connect any two open curves with well defined mathematical definitions as well as pairs of…

Biological Physics · Physics 2019-10-04 Seyed A. Sabok-Sayr , Wilma K. Olson

Strongly correlated materials exhibit complex electronic phenomena that are challenging to capture with traditional theoretical methods, yet understanding these systems is crucial for discovering new quantum materials. Addressing the…

Strongly Correlated Electrons · Physics 2024-11-22 Egor Agapov , Oriol Bertomeu , Andrés Carballo , Christian B. Mendl , Aaron Sander

A tandem cell is proposed for DNA sequencing in which an exonuclease enzyme cleaves bases (mononucleotides) from a strand of DNA for identification inside a nanopore. It has two nanopores and three compartments with the structure [cis1,…

Biomolecules · Quantitative Biology 2014-08-21 G. Sampath

We present a coarse-grained model of DNA-functionalized colloids that is computationally tractable. Importantly, the model parameters are solely based on experimental data. Using this highly simplified model, we can predict the phase…

DNA strand displacement systems have proven themselves to be fertile substrates for the design of programmable molecular machinery and circuitry. Domain-level reaction enumerators provide the foundations for molecular programming languages…

Computational Engineering, Finance, and Science · Computer Science 2020-06-05 Casey Grun , Karthik Sarma , Brian Wolfe , Seung Woo Shin , Erik Winfree

DNA nanostructures are made using synthetic DNA strands, the sequences of which are designed such that they will self-assemble into the desired form by hybridization of complementary domains. Various structures and devices have been…

Biological Physics · Physics 2015-06-02 Katherine E. Dunn

A cell dynamics method for domain separation of diblock copolymers (DBCPs) interacting with nanoparticles (NPs) whose diffusion coefficients depend on chain configuration is proposed for self-assembly of DBCP/NP composites. Increasing NP…

Materials Science · Physics 2009-04-02 Fabio D. A. Aarao Reis

Molecular motor proteins form the basis of cellular dynamics. Recently, notable efforts have led to the creation of their DNA-based mimics, which can carry out complex nanoscale motion. However, such functional analogues have not yet been…

Biological Physics · Physics 2021-05-14 Kerstin Goepfrich , Maximilian J. Urban , Christoph Frey , Ilia Platzman , Joachim P. Spatz , Na Liu

The pursuit of green methodologies for fabricating optoelectronic devices necessitates the adoption of self-assembly-based strategies to engineer efficient and sustainable platforms. Microbubble lithography (MBL) stands out as a directed…

Applied Physics · Physics 2025-06-12 Anand Dev Ranjan , Dhananjay Mahapatra , Partha Mitra , Ayan Banerjee

We use simple analytic arguments and lattice-based computer simulations to study the growth of structures made from a large number of distinct component types. Components possess 'designed' interactions, chosen to stabilize an equilibrium…

Soft Condensed Matter · Physics 2014-08-25 Lester O. Hedges , Ranjan V. Mannige , Stephen Whitelam

Colloidal self-assembly allows rational design of structures on the micrometer and submicrometer scale. One architecture that can generate complete 3D photonic band gaps is the diamond cubic lattice, which has remained difficult to realize…

Applied Physics · Physics 2024-06-11 Gregor Posnjak , Xin Yin , Paul Butler , Oliver Bienek , Mihir Dass , Ian D. Sharp , Tim Liedl

Bottom-up fabrication of inorganic nanostructures is emerging as an alternative to classical top-down approaches, offering precise nanometer-scale control at relatively low cost and effort. In particular, DNA nanostructures provide…

Under appropriate conditions, mixtures of cationic and neutral lipids and DNA in water condense into complexes in which DNA strands form local 2D smectic lattices intercalated between lipid bilayer membranes in a lamellar stack. These…

Soft Condensed Matter · Physics 2009-10-31 L. Golubovic , T. C. Lubensky , C. S. O'Hern

Using a statistical mechanical model and numerical simulations, we provide the design principle for the bridging strength ($\xi$) and linker density ($\rho$) dependent superselectivity in linker-mediated multivalent nanoparticle adsorption.…

Soft Condensed Matter · Physics 2024-03-15 Xiuyang Xia , Ran Ni

We analyze the structure of DNA molecules of different organisms by using the additive Markov chain approach. Transforming nucleotide sequences into binary strings, we perform statistical analysis of the corresponding "texts". We develop…

Other Quantitative Biology · Quantitative Biology 2014-11-14 S. S. Melnik , O. V. Usatenko

Bottom-up assembly of nanocrystals (NCs) into ordered arrays, or superlattices (SLs), is a promising route to design materials with new functionalities, but the degree of control over assembly into functional structures remains challenging.…

We introduce and numerically study a model designed to mimic the bulk behavior of a system composed of single-stranded DNA dendrimers. Complementarity of the base sequences of different strands results in the formation of strong cooperative…

Soft Condensed Matter · Physics 2009-11-11 Francis W. Starr , Francesco Sciortino