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Vasculature is known to be of key biological significance, especially in the study of cancer. As such, considerable effort has been focused on the automated measurement and analysis of vasculature in medical and pre-clinical images. In…
Medical image segmentation has been so far achieving promising results with Convolutional Neural Networks (CNNs). However, it is arguable that in traditional CNNs, its pooling layer tends to discard important information such as positions.…
Automated detection and segmentation of surgical devices, such as catheters or wires, in X-ray fluoroscopic images have the potential to enhance image guidance in minimally invasive heart surgeries. In this paper, we present a convolutional…
Medical image analysis using deep learning has recently been prevalent, showing great performance for various downstream tasks including medical image segmentation and its sibling, volumetric image segmentation. Particularly, a typical…
3D object recognition accuracy can be improved by learning the multi-scale spatial features from 3D spatial geometric representations of objects such as point clouds, 3D models, surfaces, and RGB-D data. Current deep learning approaches…
In this paper, we propose a method to segment regions in three-dimensional point clouds. We assume that (i) the shape and the number of regions in the point cloud are not known and (ii) the point cloud may be noisy. The method consists of…
Biomedical images often contain objects known to be spatially correlated or nested due to their inherent properties, leading to semantic relations. Examples include cell nuclei being nested within eukaryotic cells and colonies growing…
Recently, deep convolutional neural networks have achieved great success for medical image segmentation. However, unlike segmentation of natural images, most medical images such as MRI and CT are volumetric data. In order to make full use…
The irregular geometry and high inter-slice variability in computerized tomography (CT) scans of the human pancreas make an accurate segmentation of this crucial organ a challenging task for existing data-driven deep learning methods. To…
Nuclei appear small in size, yet, in real clinical practice, the global spatial information and correlation of the color or brightness contrast between nuclei and background, have been considered a crucial component for accurate nuclei…
Nuclei detection is an important task in the histology domain as it is a main step toward further analysis such as cell counting, cell segmentation, study of cell connections, etc. This is a challenging task due to the complex texture of…
Aims. We aim to characterize the properties of the stellar populations in the central few hundred parsecs of nearby galactic nuclei; specifically their age, mass, and 3D geometry. Methods. We use spatially resolved spectroscopic…
Highly clumped nuclei clusters captured in fluorescence in situ hybridization microscopy images are common histology entities under investigations in a wide spectrum of tissue-related biomedical investigations. Due to their large scale in…
Accurate detection and segmentation of cone cells in the retina are essential for diagnosing and managing retinal diseases. In this study, we used advanced imaging techniques, including confocal and non-confocal split detector images from…
Early diagnosis is essential for the successful treatment of bowel cancers including colorectal cancer (CRC) and capsule endoscopic imaging with robotic actuation can be a valuable diagnostic tool when combined with automated image…
We introduce polystar bodies: compact starshaped sets whose gauge or radial functions are expressible by polynomials, enabling tractable computations, such as that of intersection bodies. We prove that polystar bodies are uniformly dense in…
Computer Aided Diagnosis has emerged as an indispensible technique for validating the opinion of radiologists in CT interpretation. This paper presents a deep 3D Convolutional Neural Network (CNN) architecture for automated CT scan-based…
Cell nuclei detection is a challenging research topic because of limitations in cellular image quality and diversity of nuclear morphology, i.e. varying nuclei shapes, sizes, and overlaps between multiple cell nuclei. This has been a topic…
We propose an attention mechanism for 3D medical image segmentation. The method, named segmentation-by-detection, is a cascade of a detection module followed by a segmentation module. The detection module enables a region of interest to…
Tracking cells in 3D at high speed continues to attract extensive attention for many biomedical applications, such as monitoring immune cell migration and observing tumor metastasis in flowing blood vessels. Here, we propose a deep…