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Radon transform is widely used in physical and life sciences and one of its major applications is the X-ray computed tomography (X-ray CT), which is significant in modern health examination. The Radon inversion or image reconstruction is…

Computer Vision and Pattern Recognition · Computer Science 2018-08-10 Ji He , Jianhua Ma

Background: Intensity-modulated proton therapy (IMPT) using pencil beam technique scans tumor in a layer by layer, then spot by spot manner. It can provide highly conformal dose to tumor targets and spare nearby organs-at-risk (OAR). Fast…

Medical Physics · Physics 2024-11-28 Aoxiang Wang , Ya-Nan Zhu , Jufri Setianegara , Yuting Lin , Peng Xiao , Qingguo Xie , Hao Gao

Introduction: The present study on the development and evaluation of an automated brain tumor segmentation technique based on deep learning using the 3D U-Net model. Objectives: The objective is to leverage state-of-the-art convolutional…

Image and Video Processing · Electrical Eng. & Systems 2024-04-10 Suman Sourabh , Murugappan Valliappan , Narayana Darapaneni , Anwesh R P

The choice of learning rate (LR) functions and policies has evolved from a simple fixed LR to the decaying LR and the cyclic LR, aiming to improve the accuracy and reduce the training time of Deep Neural Networks (DNNs). This paper presents…

Machine Learning · Computer Science 2022-10-25 Yanzhao Wu , Ling Liu

In radiotherapy, the internal movement of organs between treatment sessions causes errors in the final radiation dose delivery. Motion models can be used to simulate motion patterns and assess anatomical robustness before delivery.…

To study radiotherapy-related adverse effects, detailed dose information (3D distribution) is needed for accurate dose-effect modeling. For childhood cancer survivors who underwent radiotherapy in the pre-CT era, only 2D radiographs were…

Purpose: This paper describes a new method to apply deep-learning algorithms for automatic segmentation of radiosensitive organs from 3D tomographic CT images before computing organ doses using a GPU-based Monte Carlo code. Methods: A deep…

Medical Physics · Physics 2020-09-09 Zhao Peng , Xi Fang , Pingkun Yan , Hongming Shan , Tianyu Liu , Xi Pei , Ge Wang , Bob Liu , Mannudeep K. Kalra , X. George Xu

Dose prediction is an area of ongoing research that facilitates radiotherapy planning. Most commercial models utilise imaging data and intense computing resources. This study aimed to predict the dose-volume of rectum and bladder from…

We propose an adaptive design for early phase drug combination cancer trials with the goal of estimating the maximum tolerated dose (MTD). A nonparametric Bayesian model, using beta priors truncated to the set of partially ordered dose…

Applications · Statistics 2019-10-22 Zahra S. Razaee , Galen Wien-Cook , Mourad Tighiouart

Purpose: Intensity-modulated proton therapy (IMPT) offers precise tumor coverage while sparing organs at risk (OARs) in head and neck (H&N) cancer. However, its sensitivity to anatomical changes requires frequent adaptation through online…

Classification of cancer cellularity within tissue samples is currently a manual process performed by pathologists. This process of correctly determining cancer cellularity can be time intensive. Deep Learning (DL) techniques in particular…

Image and Video Processing · Electrical Eng. & Systems 2022-11-10 Jacob D. Beckmann , Kosta Popovic

In this paper, we present a deep learning (DL) algorithm for channel estimation in communication systems. We consider the time-frequency response of a fast fading communication channel as a two-dimensional image. The aim is to find the…

Information Theory · Computer Science 2019-02-20 Mehran Soltani , Vahid Pourahmadi , Ali Mirzaei , Hamid Sheikhzadeh

Recently, deep learning (DL)-based methods for the generation of synthetic computed tomography (sCT) have received significant research attention as an alternative to classical ones. We present here a systematic review of these methods by…

Medical Physics · Physics 2021-08-30 Maria Francesca Spadea , Matteo Maspero , Paolo Zaffino , Joao Seco

Deep learning, through the use of neural networks, has demonstrated remarkable ability to automate many routine tasks when presented with sufficient data for training. The neural network architecture (e.g. number of layers, types of layers,…

Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Melika Filvantorkaman , Maral Filvan Torkaman

High-Resolution three-dimensional (3D) radio maps (RMs) provide rich information about the radio landscape that is essential to a myriad of wireless applications in the future wireless networks. Although deep learning (DL) methods have…

Signal Processing · Electrical Eng. & Systems 2026-04-02 Lin Zhu , Weifeng Zhu , Shuowen Zhang , Giuseppe Caire , Liang Liu

Recently, deep learning (DL) has automated and accelerated the clinical radiation therapy (RT) planning significantly by predicting accurate dose maps. However, most DL-based dose map prediction methods are data-driven and not applicable…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Jie Zeng , Zeyu Han , Xingchen Peng , Jianghong Xiao , Peng Wang , Yan Wang

A multicompartment mathematical model is presented with the goal of studying the role of dose-dense protocols in the context of combination cancer chemotherapy. Dose-dense protocols aim at reducing the period between courses of chemotherapy…

Populations and Evolution · Quantitative Biology 2019-09-04 Álvaro G. López , Kelly C. Iarosz , Antonio M. Batista , Jesús M. Seoane , Ricardo L. Viana , Miguel A. F. Sanjuán

On account of its many successes in inference tasks and denoising applications, Dictionary Learning (DL) and its related sparse optimization problems have garnered a lot of research interest. While most solutions have focused on single…

Machine Learning · Computer Science 2020-10-22 Wen Tang , Emilie Chouzenoux , Jean-Christophe Pesquet , Hamid Krim

In the past decades mathematical optimization has found its way into radiation therapy and has made profound practice changing impact. Today, virtually all advanced treatment delivery methods, such as IMRT, VMAT, tomotherapy, LDR/HDR…

Medical Physics · Physics 2018-10-31 Bram L. Gorissen , Jan Unkelbach , Thomas R. Bortfeld