Related papers: A Multiphase Model of Growth Factor-Regulated Athe…
In this paper, we present the empirical investigation results on the neuroendocrine system by bipartite graphs. This neuroendocrine network model can describe the structural characteristic of neuroendocrine system. The act degree…
The displacement of a fluid by another less viscous one in a quasi-two dimensional geometry typically leads to complex fingering patterns. In an isotropic system, dense-branching growth arises, which is characterized by repeated…
Solidification pattern during nonequilibrium crystallization is among the most important microstructures in the nature and technical realms. Phase field crystal (PFC) model could simulate the pattern formation during equilibrium…
Gliomas are primary brain tumors with a high invasive potential and infiltrative spread. Among them, glioblastoma multiforme (GBM) exhibits microvascular hyperplasia and pronounced necrosis triggered by hypoxia. Histological samples showing…
Stroke is the second most frequent cause of death worldwide with a considerable economic burden on the health systems. In about 15% of strokes, atherosclerotic carotid plaques (ACPs) constitute the main etiological factor. Early detection…
Microtubules (MTs) are cytoplasmic protein polymers that are essential for fundamental cellular processes including the maintenance of cell shape, organelle transport and formation of the mitotic spindle. Microtubule dynamic instability is…
Adhesion-independent migration is a prominent mode of cell motility in confined environments, yet the physical principles that guide such movement remain incompletely understood. We present a phase-field model for simulating the motility of…
We investigate calcium carbonate scale formation at high Reynolds numbers in a large pipe rig facility. The calcium carbonate solution is produced from the injection, at a T-joint inlet, of pH-stabilized sodium carbonate and calcium…
In the present paper, an asymptotic model is constructed for the short-time deformation of an articular cartilage layer modeled as transversely isotropic, transversely homogeneous (TITH) biphasic material. It is assumed that the layer…
Accumulation of particles while flowing past constrictions is a ubiquitous phenomenon observed in diverse systems. Some of the common examples are jamming of salt crystals near the orifice of salt shakers, clogging of filter systems,…
We present a theoretical analysis of the dynamic structure factor (DSF) of a liquid at and below the mode coupling critical temperature $T_c$, by developing a self-consistent theoretical treatment which includes the contributions both from…
Background The epidermal growth factor receptor (EGFR) is frequently overexpressed in many cancers, including non-small cell lung cancer (NSCLC). In silcio modeling is considered to be an increasingly promising tool to add useful insights…
The actin cortex is a thin layer of actin, myosin, and actin binding proteins that underlies the membrane of most animal cells. It is highly dynamic and can undergo remodelling on time-scales of tens of seconds thanks to protein turnover…
We report numerical investigations of a three-dimensional model of diffusive growth of fine particles, the internal structure of which corresponds to different crystal lattices. A growing cluster (particle) is immersed in, and exchanges…
Active gels are a class of biologically-relevant material containing embedded agents that spontaneously generate forces acting on a sparse filament network. In vitro experiments of protein filaments and molecular motors have revealed a…
We present here a population structured model to describe the dynamics of macrophage cells. The model involves the interactions between modified LDL, monocytes/macrophages, cytokines and foam cells. The key assumption is that the individual…
Anatomy shape modeling is a fundamental problem in medical data analysis. However, the geometric complexity and topological variability of anatomical structures pose significant challenges to accurate anatomical shape generation. In this…
Type I collagen is the main component of the extra-cellular matrix (ECM). In vitro, under a narrow window of physico-chemical conditions, type I collagen self-assembles to form complex supramolecular architectures reminiscent of those found…
We introduce an off-lattice model with continuous particle distances and pair-potential interactions which allows for the efficient simulation of strained heteroepitaxial growth by means of kinetic Monte Carlo (KMC) simulations. We discuss…
Developing clinically viable tissue-engineered cardiovascular implants remains a formidable challenge. Achieving reliable and durable outcomes requires a deeper understanding of the fundamental mechanisms driving tissue evolution during in…