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Convolutional autoencoders have emerged as popular methods for unsupervised defect segmentation on image data. Most commonly, this task is performed by thresholding a pixel-wise reconstruction error based on an $\ell^p$ distance. This…

Ocular Myasthenia Gravis (OMG) is a rare and challenging disease to detect in its early stages, but symptoms often first appear in the eye muscles, such as drooping eyelids and double vision. Ocular images can be used for early diagnosis by…

We propose a new deep learning approach for automatic detection and segmentation of fluid within retinal OCT images. The proposed framework utilizes both ResNet and Encoder-Decoder neural network architectures. When training the network, we…

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Automated surface segmentation of retinal layer is important and challenging in analyzing optical coherence tomography (OCT). Recently, many deep learning based methods have been developed for this task and yield remarkable performance.…

30 million Optical Coherence Tomography (OCT) imaging tests are issued annually to diagnose various retinal diseases, but accurate diagnosis of OCT scans requires trained eye care professionals who are still prone to making errors. With…

Current state-of-the-art object detection algorithms still suffer the problem of imbalanced distribution of training data over object classes and background. Recent work introduced a new loss function called focal loss to mitigate this…

Super-resolution using deep neural networks typically relies on highly curated training sets that are often unavailable in clinical deployment scenarios. Using loss functions that assume Gaussian-distributed residuals makes the learning…

Accurate detection and segmentation of cone cells in the retina are essential for diagnosing and managing retinal diseases. In this study, we used advanced imaging techniques, including confocal and non-confocal split detector images from…

A major cause of irreversible visual impairment is angle-closure glaucoma, which can be screened through imagery from Anterior Segment Optical Coherence Tomography (AS-OCT). Previous computational diagnostic techniques address this…

Automated drusen segmentation in retinal optical coherence tomography (OCT) scans is relevant for understanding age-related macular degeneration (AMD) risk and progression. This task is usually performed by segmenting the top/bottom…

Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…

Raster-scan optoacoustic mesoscopy (RSOM) is a powerful, non-invasive optical imaging technique for functional, anatomical, and molecular skin and tissue analysis. However, both the manual and the automated analysis of such images are…

Traditional deep learning methods in medical imaging often focus solely on segmentation or classification, limiting their ability to leverage shared information. Multi-task learning (MTL) addresses this by combining both tasks through…

Retinal imaging has emerged as a promising method of addressing this challenge, taking advantage of the unique structure of the retina. The retina is an embryonic extension of the central nervous system, providing a direct in vivo window…

Fundus image segmentation on unseen domains is challenging, especially for the over-parameterized deep models trained on the small medical datasets. To address this challenge, we propose a method named Adaptive Feature-fusion Neural Network…

Deep-learning-based approaches for retinal lesion segmentation often require an abundant amount of precise pixel-wise annotated data. However, coarse annotations such as circles or ellipses for outlining the lesion area can be six times…

Automated segmentation of cancerous lesions in PET/CT scans is a crucial first step in quantitative image analysis. However, training deep learning models for segmentation with high accuracy is particularly challenging due to the variations…

High fidelity segmentation of both macro and microvascular structure of the retina plays a pivotal role in determining degenerative retinal diseases, yet it is a difficult problem. Due to successive resolution loss in the encoding phase…

Image segmentation is critically important in almost all medical image analysis for automatic interpretations and processing. However, it is often challenging to perform image segmentation due to data imbalance between intra- and…