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Cellularized tissue and polymer networks can both transition from floppy to rigid as a function of their control parameters, and, yet, the two systems often mechanically interact, which may affect their respective rigidities. To study this…

Cell Behavior · Quantitative Biology 2020-06-30 Amanda Parker , M. Cristina Marchetti , M. Lisa Manning , J. M. Schwarz

Interactions mediated by the cell membrane between inclusions, such as membrane proteins or antimicrobial peptides, play important roles in their biological activity. They also constitute a fascinating challenge for physicists, since they…

Biological Physics · Physics 2019-03-15 Anne-Florence Bitbol , Doru Constantin , Jean-Baptiste Fournier

Experimentally measuring the elastic properties of thin biological surfaces is non-trivial, particularly when they are curved. One technique that may be used is the indentation of a thin sheet of material by a rigid indenter, whilst…

The formation of microparticles requires the bending of the plasma membrane away from the cytosol. The capcity of the cell membrane to form a microparticle, and the rate of membrane deformation, are controlled by multiple factors, including…

Soft Condensed Matter · Physics 2024-02-13 Arijit Mahapatra , Sage A. Malingen , Padmini Rangamani

Cell layers eliminate unwanted cells through the extrusion process, which underlines healthy versus flawed tissue behaviors. Although several biochemical pathways have been identified, the underlying mechanical basis including the forces…

Soft Condensed Matter · Physics 2023-04-20 Siavash Monfared , Guruswami Ravichandran , Jose E. Andrade , Amin Doostmohammadi

It is widely appreciated that surface tension can dominate the behavior of liquids at small scales. Solids also have surface stresses of a similar magnitude, but they are usually overlooked. However, recent work has shown that these can…

Soft Condensed Matter · Physics 2017-05-24 Robert W. Style , Anand Jagota , C. -Y. Hui , Eric R. Dufresne

We study the effect of surface tension of the phase boundary in the dynamics of an expanding fluid. A fluid at local thermal equilibrium, but has a slowly varying temperature profile, like the plasma formed in heavy ion collisions, will…

Nuclear Theory · Physics 2022-01-11 Sanatan Digal , P. S. Saumia

Transport of microscopic objects across biological membranes usually involves membrane deformation to enclose the object followed by detachment of the engulfed particle. However, in artificial membranes, this last topological remodelling…

Soft Condensed Matter · Physics 2025-03-25 Florent Fessler , Pierre Muller , Antonio Stocco

During the life of animals, epithelial tissues undergo extensive deformations--first to form organs during embryogensis and later to preserve integrity and function in adulthood. To what extent these deformations resemble that of non-living…

Soft Condensed Matter · Physics 2025-04-23 Urska Andrensek , Matej Krajnc

We study the indentation of a free-standing lipid membrane suspended over a nanopore on a hydrophobic substrate by means of molecular dynamics simulations. We find that in the course of indentation, the membrane bends at the point of…

Soft Condensed Matter · Physics 2011-08-26 Chen-Hsi Huang , Pai-Yi Hsiao , Fan-Gang Tseng , Shih-Kang Fan , Chien-Chung Fu , Rong-Long Pan

On the basis of a previous theoretical approach to the plastic flow of highly refined materials, a physical explanation for diffusion bonding is essayed, which yields closed--form equations relating the bonding progress with time,…

Materials Science · Physics 2010-07-02 Miguel Lagos , César Retamal

Lipid-bilayers are the fundamental constituents of the walls of most living cells and lipid vesicles, giving them shape and compartment. The formation and growing of pores in a lipid bilayer have attracted considerable attention from an…

Soft Condensed Matter · Physics 2015-06-19 Meisam Asgari , Aisa Biria

The adhesion bonds connecting a lipid bilayer to an underlying surface may undergo a condensation transition resulting from an interplay between a short range attractive potential between them, and a long range fluctuation-induced potential…

Soft Condensed Matter · Physics 2016-02-25 Nadiv Dharan , Oded Farago

The elastic deformation of a soft solid induced by capillary forces crucially relies on the excess stress inside the solid-liquid interface. While for a liquid-liquid interface this "surface stress" is strictly identical to the "surface…

Soft Condensed Matter · Physics 2015-06-17 Joost H. Weijs , Jacco H. Snoeijer , Bruno Andreotti

In development and homeostasis, multi-cellular systems exhibit spatial and temporal heterogeneity in their biochemical and mechanical properties. Nevertheless, it remains unclear how spatiotemporally heterogeneous forces affect the…

Soft Condensed Matter · Physics 2022-02-18 Takaki Yamamoto , Daniel M. Sussman , Tatsuo Shibata , M. Lisa Manning

Motivated by recent experiments on biomimetic membranes exposed to several aqueous phases, we theoretically study the morphology of a membrane in contact with a liquid droplet formed via aqueous phase separation. We concentrate on membranes…

Soft Condensed Matter · Physics 2012-02-07 Halim Kusumaatmaja , Reinhard Lipowsky

Utilizing colloidal probe, lateral force microscopy and simultaneous confocal microscopy, combined with finite element analysis, we investigate the mechanism of static friction for a microparticle on a soft, adhesive surface. We find that…

Soft Condensed Matter · Physics 2023-04-26 Justin D. Glover , Xingwei Yang , Rong Long , Jonathan T. Pham

Motivated to understand the behavior of biological filaments interacting with membranes of various types, we study a theoretical model for the shape and thermodynamics of intrinsically-helical filaments bound to curved membranes. We show…

Soft Condensed Matter · Physics 2016-11-03 D. A. Quint , A. Gopinathan , G. M. Grason

Membrane pores are implicated in several critical functions, including cell fusion and the transport of signaling molecules for intercellular communication. However, these structural features are often difficult to probe directly. Droplet…

Soft Condensed Matter · Physics 2025-11-13 Nivedina A. Sarma , David A. King , Xuefei Wu , Brett A. Helms , Paul D. Ashby , Thomas P. Russell , Ahmad K. Omar

Comparison of a few simple models of fluid and solid membranes illustrates how shear stresses can arise from a bending energy through a coupling between curvature and surface stresses, a feature incidental to the fluid or solid nature of…

Soft Condensed Matter · Physics 2025-06-03 S. Dharmavaram , J. A. Hanna