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The lateral diffusion and trapping of protein receptors within the postsynaptic membrane of a neuron plays a key role in determining the strength of synaptic connections and their regulation during learning and memory. In this paper we…

Statistical Mechanics · Physics 2023-07-19 Paul C Bressloff

Diffusion MRI (dMRI) provides contrast that reflect diffusing spins' interactions with microstructural features of biological systems, but its specificity remains limited due to the ambiguity of its relation to the underlying…

Medical Physics · Physics 2022-03-29 Jonas L. Olesen , Leif Østergaard , Noam Shemesh , Sune N. Jespersen

Intra-voxel models of the diffusion signal are essential for interpreting organization of the tissue environment at micrometer level with data at millimeter resolution. Recent advances in data driven methods have enabled direct compari-son…

Detail features of magnetic resonance images play a cru-cial role in accurate medical diagnosis and treatment, as they capture subtle changes that pose challenges for doc-tors when performing precise judgments. However, the widely utilized…

Computer Vision and Pattern Recognition · Computer Science 2024-05-10 Mengxiao Geng , Jiahao Zhu , Xiaolin Zhu , Qiqing Liu , Dong Liang , Qiegen Liu

Quantifying the myelin sheath radius of myelinated axons in vivo is important for understanding, diagnosing, and monitoring various neurological disorders. Despite advancements in diffusion MRI (dMRI) microstructure techniques, there are…

The deformation evolution of giant dipole resonance (GDR), in the chains of Sm and Nd isotopes, are investigated in the framework of an extended quantum molecular dynamics (EQMD) model. The mass number dependence of resonance peak position…

Nuclear Theory · Physics 2017-06-06 S. S. Wang , Y. G. Ma , X. G. Cao , W. B. He , H. Y. Kong , C. W. Ma

Although rodent models are a predominant study model in neuroscience research, research investigating healthy rodent brain maturation remains limited. This motivates further study of normal brain maturation in rodents to exclude confounds…

Medical Physics · Physics 2023-09-28 Naila Rahman , Jake Hamilton , Kathy Xu , Arthur Brown , Corey A. Baron

The research field of two dimensional (2D) materials strongly relies on optical microscopy characterization tools to identify atomically thin materials and to determine their number of layers. Moreover, optical microscopy-based techniques…

In this viewpoint article, we discuss the electric properties of the medium around neurons, which are important to correctly interpret extracellular potentials or electric field effects in neural tissue. We focus on how these electric…

Neurons and Cognition · Quantitative Biology 2017-03-02 Claude Bedard , Jean-Marie Gomes , Thierry Bal , Alain Destexhe

Multiple sclerosis is an inflammatory disorder of the central nervous system. Quantitative MRI has huge potential to provide intrinsic and normative values of tissue properties useful for diagnosis, prognosis and ultimately clinical…

Image and Video Processing · Electrical Eng. & Systems 2023-10-03 Haykel Snoussi , Julien Cohen-Adad , Benoit Combes , Elise Bannier , Slimane Tounekti , Anne Kerbrat , Christian Barillot , Emmanuel Caruyer

Reconstructing visual stimuli from human brain activities provides a promising opportunity to advance our understanding of the brain's visual system and its connection with computer vision models. Although deep generative models have been…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Jingyuan Sun , Mingxiao Li , Marie-Francine Moens

Neuron segmentation in electron microscopy (EM) aims to reconstruct the complete neuronal connectome; however, current deep learning-based methods are limited by their reliance on large-scale training data and extensive, time-consuming…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Liuyun Jiang , Yanchao Zhang , Jinyue Guo , Yizhuo Lu , Ruining Zhou , Hua Han

The different active roles of neurons and astrocytes during neuronal activation are associated with the metabolic processes necessary to supply the energy needed for their respective tasks at rest and during neuronal activation. Metabolism,…

Tissues and Organs · Quantitative Biology 2022-11-07 Gideon Idumah , Erkki Somersalo , Daniela Calvetti

The human brain is a complex system requiring both macroscopic and microscopic components for comprehensive understanding. However, mapping nonlinear relationships between these scales remains challenging due to technical limitations and…

Image and Video Processing · Electrical Eng. & Systems 2025-10-28 Sooyoung Kim , Joonwoo Kwon , Junbeom Kwon , Jungyoun Janice Min , Sangyoon Bae , Yuewei Lin , Shinjae Yoo , Jiook Cha

This paper investigates score-based diffusion models when the underlying target distribution is concentrated on or near low-dimensional manifolds within the higher-dimensional space in which they formally reside, a common characteristic of…

Machine Learning · Computer Science 2025-01-03 Gen Li , Yuling Yan

Cortical thickness measurements from magnetic resonance imaging, an important biomarker in many neurodegenerative and neurological disorders, are derived by many tools from an initial voxel-wise tissue segmentation. White matter (WM)…

Image and Video Processing · Electrical Eng. & Systems 2025-03-27 Vinzenz Uhr , Ivan Diaz , Christian Rummel , Richard McKinley

Diffusion-weighted magnetic resonance imaging in brain white matter probes tissue microstructure and allows for the estimation of compartmental diffusion parameters. Recently, it became apparent that traditional single-direction diffusion…

Biological Physics · Physics 2018-09-20 Marco Reisert , Valerij G. Kiselev , Bibek Dhital

Diffusion Tensor Imaging (DTI) provides the possibility of estimating the location and course of eloquent structures in the human brain. Knowledge about this is of high importance for preoperative planning of neurosurgical interventions and…

Computer Vision and Pattern Recognition · Computer Science 2011-03-11 Miriam H. A. Bauer , Jan Egger , Daniela Kuhnt , Sebastiano Barbieri , Jan Klein , Horst K. Hahn , Bernd Freisleben , Christopher Nimsky

When transmitting polarised light through histological brain sections, different types of diattenuation (polarisation-dependent attenuation of light) can be observed: In some brain regions, the light is minimally attenuated when it is…

Medical Physics · Physics 2019-02-22 Miriam Menzel , Markus Axer , Katrin Amunts , Hans De Raedt , Kristel Michielsen

We numerically investigate the distribution of Drude weights $D$ of many-body states in disordered one-dimensional interacting electron systems across the transition to a many-body localized phase. Drude weights are proportional to the…

Mesoscale and Nanoscale Physics · Physics 2016-11-23 Michele Filippone , Piet W. Brouwer , Jens Eisert , Felix von Oppen