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Magnetic resonance microscopy images at cellular resolution (< 10 microns) are limited by diffusion. SNR and spatial resolution suffer from the dephasing of transverse magnetization caused by diffusion of spins in strong gradients. Such…

Advanced diffusion MRI models are being explored to study the complex microstructure of the brain with higher accuracy. However, these techniques require long acquisition times. Simultaneous multi-slice (SMS) accelerates data acquisition by…

Medical Physics · Physics 2022-01-26 L. Tugan Muftuler , Andrew S. Nencka , Kevin M. Koch

Porous or biological materials comprise a multitude of micro-domains containing water. Diffusion-weighted magnetic resonance measurements are sensitive to the anisotropy of the thermal motion of such water. This anisotropy can be due to the…

Applied Physics · Physics 2021-05-05 Cem Yolcu , Magnus Herberthson , Carl-Fredrik Westin , Evren Özarslan

Diffusion tensor imaging provides increased sensitivity to microstructural tissue changes compared to conventional anatomical imaging but also presents limited specificity. To tackle this problem, the DIAMOND model subdivides the voxel…

Accurate brain tumor diagnosis relies on the assessment of multiple Magnetic Resonance Imaging (MRI) sequences. However, in clinical practice, the acquisition of certain sequences may be affected by factors like motion artifacts or contrast…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Moinak Bhattacharya , Saumya Gupta , Annie Singh , Chao Chen , Gagandeep Singh , Prateek Prasanna

Energy carrier transport and recombination in emerging semiconductors can be directly monitored with optical microscopy, leading to the measurement of the diffusion coefficient (D), a critical property for design of efficient optoelectronic…

Data-dependent metrics are powerful tools for learning the underlying structure of high-dimensional data. This article develops and analyzes a data-dependent metric known as diffusion state distance (DSD), which compares points using a…

Machine Learning · Statistics 2020-03-10 Lenore Cowen , Kapil Devkota , Xiaozhe Hu , James M. Murphy , Kaiyi Wu

Diffusion-encoded magnetic resonance (MR) experiments can provide important insights into the microstructural characteristics of a variety of biological tissues and other fluid- or gas-filled porous media. The physics of diffusion encoding…

Medical Physics · Physics 2021-09-30 Justin P. Haldar

Diffusion magnetic resonance imaging (dMRI) provides critical insights into the microstructural and connectional organization of the human brain. However, the availability of high-field, open-access datasets that include raw k-space data…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Shanshan Wang , Shoujun Yu , Jian Cheng , Sen Jia , Changjun Tie , Jiayu Zhu , Haohao Peng , Yijing Dong , Jianzhong He , Fan Zhang , Yaowen Xing , Xiuqin Jia , Qi Yang , Qiyuan Tian , Hua Guo , Guobin Li , Hairong Zheng

Diffusion weighted imaging techniques permit us to infer microstructural detail in biological tissue in vivo and noninvasively. Modern sequences are based on advanced diffusion encoding schemes, allowing probing of more revealing measures…

Significance: This work targets the contamination of optical signals by superficial hemodynamics, which is one of the chief hurdles in non-invasive optical measurements of the human brain. Aim: To identify optimal source-detector distances…

Medical Physics · Physics 2023-01-05 Giles Blaney , Cristianne Fernandez , Angelo Sassaroli , Sergio Fantini

The dependent scattering effect (DSE), which arises from the wave nature of electromagnetic radiation, is a critical mechanism affecting the radiative properties of micro/nanoscale discrete disordered media (DDM). In the last a few decades,…

Mesoscale and Nanoscale Physics · Physics 2020-09-01 B. X. Wang , C. Y. Zhao

Radio-frequency dosimetry is an important process in human safety and for compliance of related products. Recently, computational human models generated from medical images have often been used for such assessment, especially to consider…

Machine Learning · Computer Science 2020-04-29 Essam A. Rashed , Yinliang Diao , Akimasa Hirata

Purpose: To investigate the effect of anisotropic magnetic microstructure on the measurable Larmor frequency offset in media with heterogeneous magnetic susceptibility. Specific objectives were (i) validation of recently developed theory…

Soft Condensed Matter · Physics 2019-10-23 Alexander Ruh , Valerij G. Kiselev

Diffusion magnetic resonance imaging (dMRI) provides a unique tool for noninvasively probing the microstructure of the neuronal tissue. The NODDI model has been a popular approach to the estimation of tissue microstructure in many…

Computer Vision and Pattern Recognition · Computer Science 2017-04-06 Chuyang Ye

Purpose: Eddy currents might lead to image distortions in diffusion weighted echo planar imaging. A method is proposed to reduce their effects on double diffusion encoding (DDE) MRI experiments and the thereby derived microscopic fractional…

Medical Physics · Physics 2021-04-20 Lars Mueller , Andreas Wetscherek , Tristan Anselm Kuder , Frederik Bernd Laun

Magnetic resonance imaging (MRI) is a vital diagnostic tool, but its inherently long acquisition times reduce clinical efficiency and patient comfort. Recent advancements in deep learning, particularly diffusion models, have improved…

Image and Video Processing · Electrical Eng. & Systems 2026-04-28 Yuxuan Zhang , Jinkui Hao , Bo Zhou

Inflammation of brain tissue is a complex response of the immune system to the presence of toxic compounds or to cell injury, leading to a cascade of pathological processes that include glial cell activation. Noninvasive magnetic resonance…

Diffusion tensor imaging (DTI) provides crucial insights into the microstructure of the human brain, but it can be time-consuming to acquire compared to more readily available T1-weighted (T1w) magnetic resonance imaging (MRI). To address…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Shaorong Zhang , Tamoghna Chattopadhyay , Sophia I. Thomopoulos , Jose-Luis Ambite , Paul M. Thompson , Greg Ver Steeg

Estimated brain age from magnetic resonance image (MRI) and its deviation from chronological age can provide early insights into potential neurodegenerative diseases, supporting early detection and implementation of prevention strategies.…