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The CVS is composed of numerous interacting and dynamically regulated physiological subsystems which each generate measurable periodic components such that the CVS can itself be presented as a system of weakly coupled oscillators. The…

Heart rate variability (HRV), defined as the variability between consecutive heartbeats, is a surrogate measure of cardiac vagal tone. It is widely accepted that a decreased HRV is associated to several risk factors and cardiovascular…

Medical Physics · Physics 2021-05-20 Stefania Scarsoglio , Luca Ridolfi

Estimating the effect of a treatment on a given outcome, conditioned on a vector of covariates, is central in many applications. However, learning the impact of a treatment on a continuous temporal response, when the covariates suffer…

Machine Learning · Computer Science 2019-06-11 Guangyi Zhang , Reza Ashrafi , Anne Juuti , Kirsi Pietiläinen , Pekka Marttinen

The electrocardiogram (ECG) is the gold standard for non-invasive diagnosis of cardiac pathologies and is a fundamental pillar of cardiovascular medicine. Recent progress in deep learning has led to the development of robust automated…

We use topological data analysis as a tool to analyze the fit of mathematical models to experimental data. This study is built on data obtained from motion tracking groups of aphids in [Nilsen et al., PLOS One, 2013] and two random walk…

Quantitative Methods · Quantitative Biology 2018-11-13 M. Ulmer , Lori Ziegelmeier , Chad M. Topaz

Cardiopulmonary exercise testing (CPET) provides a comprehensive assessment of functional capacity by measuring key physiological variables including oxygen consumption ($VO_2$), carbon dioxide production ($VCO_2$), and pulmonary…

Machine Learning · Computer Science 2025-03-19 Muhammet Alkan , Gruschen Veldtman , Fani Deligianni

Objective: To develop and interpret a supervised variational autoencoder (VAE) model for classifying cardiotocography (CTG) signals based on pregnancy outcomes, addressing interpretability limits of current deep learning approaches.…

Machine Learning · Computer Science 2025-09-09 John Tolladay , Beth Albert , Gabriel Davis Jones

This article proposes a systematic methodological review and objective criticism of existing methods enabling the derivation of time-varying Granger-causality statistics in neuroscience. The increasing interest and the huge number of…

Applications · Statistics 2017-04-12 Sezen Cekic , Didier Grandjean , Olivier Renaud

The analysis of spatio-temporal data presents significant challenges due to the complexity and heterogeneity of movement patterns. This project proposes a data analytics tool that combines data visualization and statistical computation to…

Human-Computer Interaction · Computer Science 2025-08-01 Ivan A. Hanono Cozzetti , Ahmad Abdou

Connectionist temporal classification (CTC) is commonly adopted for sequence modeling tasks like speech recognition, where it is necessary to preserve order between the input and target sequences. However, CTC is only applied to…

Machine Learning · Computer Science 2023-12-18 Zheng Nan , Ting Dang , Vidhyasaharan Sethu , Beena Ahmed

Respiratory airflow signals provide critical insight into breathing mechanics, yet conventional analysis methods remain limited in their ability to characterize the internal structure of individual breaths. Traditional approaches treat…

Signal Processing · Electrical Eng. & Systems 2026-04-27 Victoria Ribeiro Rodrigues , Paul W. Davenport , Nicholas J. Napoli

We propose a novel approach to estimate the Cox model with temporal covariates. Our new approach treats the temporal covariates as arising from a longitudinal process which is modeled jointly with the event time. Different from the…

Methodology · Statistics 2018-02-05 Xiaoqi Zhang , Xiaobing Zhao , Yanqiao Zheng

Prognostication for comatose post-cardiac arrest patients is a critical challenge that directly impacts clinical decision-making in the ICU. Clinical information that informs prognostication is collected serially over time. Shortly after…

Machine Learning · Computer Science 2025-08-11 Xiaobin Shen , Jonathan Elmer , George H. Chen

CircSpaceTime is the only R package currently available that implements Bayesian models for spatial and spatio-temporal interpolation of circular data. Such data are often found in applications where, among the many, wind directions, animal…

Applications · Statistics 2020-01-03 Giovanna Jona Lasinio , Mario Santoro , Gianluca Mastrantonio

Correlated survival data are prevalent in various clinical settings and have been extensively discussed in literature. One of the most common types of correlated survival data is clustered survival data, where the survival times from…

Methodology · Statistics 2024-08-02 Chengqian Xian , Camila P. E. de Souza , Wenqing He , Felipe F. Rodrigues , Renfang Tian

We consider calculation of capital requirements when the underlying economic scenarios are determined by simulatable risk factors. In the respective nested simulation framework, the goal is to estimate portfolio tail risk, quantified via…

Risk Management · Quantitative Finance 2018-05-18 Michael Ludkovski , James Risk

This study introduces a data-driven, machine learning-based method to detect suitable control variables and instruments for assessing the causal effect of a treatment on an outcome in observational data. Our approach tests the joint…

Econometrics · Economics 2026-05-20 Nicolas Apfel , Julia Hatamyar , Martin Huber , Jannis Kueck

Time series data are often obtained only within a limited time range due to interruptions during observation process. To classify such partial time series, we need to account for 1) the variable-length data drawn from 2) different…

Machine Learning · Computer Science 2022-07-14 Azusa Sawada , Taiki Miyagawa , Akinori F. Ebihara , Shoji Yachida , Toshinori Hosoi

The methods used so far for the analysis of time changes in population health suffer from the lack of causality in their design. This results in problems with their implementation and interpretation. Here the method is presented with…

Applications · Statistics 2016-02-19 Vladislav Moltchanov

Time is an important relevance signal when searching streams of social media posts. The distribution of document timestamps from the results of an initial query can be leveraged to infer the distribution of relevant documents, which can…

Information Retrieval · Computer Science 2017-07-26 Jinfeng Rao , Hua He , Haotian Zhang , Ferhan Ture , Royal Sequiera , Salman Mohammed , Jimmy Lin
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