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The detection of Extreme Mass Ratio Inspirals (EMRIs) is intricate due to their complex waveforms, extended duration, and low signal-to-noise ratio (SNR), making them more challenging to be identified compared to compact binary…

Instrumentation and Methods for Astrophysics · Physics 2024-05-15 Tianyu Zhao , Yue Zhou , Ruijun Shi , Zhoujian Cao , Zhixiang Ren

Background: Current mathematical quantification methods for beam symmetry are highly sensitive to noise, especially in beam profiles with significant variation. Purpose: This study evaluates the accuracy of standard radiotherapy beam…

Medical Physics · Physics 2025-09-30 Dalton H Bermudez , Wesley Culberson

Colorectal cancer (CRC) micro-satellite instability (MSI) prediction on histopathology images is a challenging weakly supervised learning task that involves multi-instance learning on gigapixel images. To date, radiology images have proven…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Quan Liu , Jiawen Yao , Lisha Yao , Xin Chen , Jingren Zhou , Le Lu , Ling Zhang , Zaiyi Liu , Yuankai Huo

The assessment of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) associated with brain changes remains a challenging task. Recent studies have demonstrated that combination of multi-modality imaging techniques can better…

Machine Learning · Computer Science 2022-09-26 Jun Yu , Zhaoming Kong , Liang Zhan , Li Shen , Lifang He

Text-To-Image (TTI) generation is significant for controlled and diverse image generation with broad potential applications. Although current medical TTI methods have made some progress in report-to-Chest-Xray (CXR) generation, their…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Peng Huang , Bowen Guo , Shuyu Liang , Junhu Fu , Yuanyuan Wang , Yi Guo

We present a system for the prediction of microsatellite instability (MSI) from H&E images of colorectal cancer using deep learning (DL) techniques customized for tissue microarrays (TMAs). The system incorporates an end-to-end image…

Computer Vision and Pattern Recognition · Computer Science 2021-10-29 Aurelia Bustos , Artemio Payá , Andres Torrubia , Rodrigo Jover , Xavier Llor , Xavier Bessa , Antoni Castells , Cristina Alenda

Balancing spectral, spatial, and temporal resolutions is a key challenge in spectral imaging. The Dual-Camera Coded Aperture Snapshot Spectral Imaging (DC-CASSI) system alleviates this trade-off but suffers from severely ill-posed…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Weiqiang Zhao , Tianzhu Liu , Yuzhe Gui , Wei Bian , Yanfeng Gu

Diffusion-weighted magnetic resonance imaging (dMRI) is widely used to assess the brain white matter. One of the most common computations in dMRI involves cross-subject tract-specific analysis, whereby dMRI-derived biomarkers are compared…

Image and Video Processing · Electrical Eng. & Systems 2023-07-12 Davood Karimi , Hamza Kebiri , Ali Gholipour

Diffusion MRI (dMRI) is essential for studying brain microstructure, but high-resolution imaging remains challenging due to the inherent trade-offs between acquisition time and signal-to-noise ratio (SNR). Conventional methods often…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Yinzhe Wu , Jiahao Huang , Fanwen Wang , Mengze Gao , Congyu Liao , Guang Yang , Kawin Setsompop

The purpose of this work is to develop a framework for single-subject analysis of diffusion tensor imaging (DTI) data. This framework (termed TOADDI) is capable of testing whether an individual tract as represented by the major eigenvector…

A large number of mathematical models have been proposed to describe the measured signal in diffusion-weighted (DW) magnetic resonance imaging (MRI) and infer properties about the white matter microstructure. However, a head-to-head…

Causal inference is essential for data-driven decision making across domains such as business engagement, medical treatment and policy making. However, research on causal discovery has evolved separately from inference methods, preventing…

Coherent diffractive imaging (CDI) enables lensless imaging with experimental simplicity and a flexible field of view, yet its resolution is fundamentally constrained by the Abbe diffraction limit. To overcome this limitation, we introduce…

Hadamard Transform Spectral Imaging (HTSI) is a multiplexing technique used to recover spectra via encoding with multi-slit masks, and is particularly useful in low photon flux applications where signal-independent noise is the dominant…

Instrumentation and Methods for Astrophysics · Physics 2025-10-24 John Nijim , Zoran Ninkov , Dmitry Vorobiev , Kevin Kearney

High Content Screening (HCS) microscopy datasets have transformed the ability to profile cellular responses to genetic and chemical perturbations, enabling cell-based inference of drug-target interactions (DTI). However, the adoption of…

Understanding the complex myocardial architecture is critical for diagnosing and treating heart disease. However, existing methods often struggle to accurately capture this intricate structure from Diffusion Tensor Imaging (DTI) data,…

Image and Video Processing · Electrical Eng. & Systems 2025-05-14 Mohini Anand , Xavier Tricoche

The corticospinal tract (CST) is a critically important white matter fiber tract in the human brain that enables control of voluntary movements of the body. Diffusion MRI tractography is the only method that enables the study of the anatomy…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Jianzhong He , Fan Zhang , Yiang Pan , Yuanjing Feng , Jarrett Rushmore , Erickson Torio , Yogesh Rathi , Nikos Makris , Ron Kikinis , Alexandra J. Golby , Lauren J. O'Donnell

Diffusion models offer a robust framework for sampling from unnormalized probability densities, which requires accurately estimating the score of the noise-perturbed target distribution. While the standard Denoising Score Identity (DSI)…

Machine Learning · Computer Science 2025-12-24 Khaled Kahouli , Romuald Elie , Klaus-Robert Müller , Quentin Berthet , Oliver T. Unke , Arnaud Doucet

Tractography is typically performed for each subject using the diffusion tensor imaging (DTI) data in its native subject space rather than in some space common to the entire study cohort. Despite performing tractography on a population…

Although existing deep learning compressed-sensing-based Magnetic Resonance Imaging (CS-MRI) methods have achieved considerably impressive performance, explainability and generalizability continue to be challenging for such methods since…

Image and Video Processing · Electrical Eng. & Systems 2023-03-14 Xiaohong Fan , Yin Yang , Ke Chen , Jianping Zhang , Ke Dong
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