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Through the use of examples, we explain one way in which applied topology has evolved since the birth of persistent homology in the early 2000s. The first applications of topology to data emphasized the global shape of a dataset, such as…

Algebraic Topology · Mathematics 2021-04-23 Henry Adams , Michael Moy

Heterogeneous data pose serious challenges to data analysis tasks, including exploration and visualization. Current techniques often utilize dimensionality reductions, aggregation, or conversion to numerical values to analyze heterogeneous…

Graphics · Computer Science 2017-10-10 Mahsa Mirzargar , Ross T. Whitaker , Robert M. Kirby

Spatial transcriptomics studies are becoming increasingly large and commonplace, necessitating simultaneous analysis of a large number of spatially resolved variables. Correspondingly, a diverse range of methodologies have been proposed to…

Quantitative Methods · Quantitative Biology 2025-09-09 James Boyle , Gregory Hamm , Eleanor Williams , Robin JG Hartman , Magnus Soderburg , Ian Henry , Michael Casey

Computational topology provides a tool, persistent homology, to extract quantitative descriptors from structured objects (images, graphs, point clouds, etc). These descriptors can then be involved in optimization problems, typically as a…

Computational Geometry · Computer Science 2026-03-27 Mathieu Carriere , Yuichi Ike , Théo Lacombe , Naoki Nishikawa

A fundamental tool in topological data analysis is persistent homology, which allows extraction of information from complex datasets in a robust way. Persistent homology assigns a module over a principal ideal domain to a one-parameter…

Algebraic Topology · Mathematics 2019-06-19 Heather A. Harrington , Nina Otter , Hal Schenck , Ulrike Tillmann

We combine standard persistent homology with image persistent homology to define a novel way of characterizing shapes and interactions between them. In particular, we introduce: (1) a mixup barcode, which captures geometric-topological…

Algebraic Topology · Mathematics 2026-05-19 Hubert Wagner , Nickolas Arustamyan , Matthew Wheeler , Peter Bubenik

This paper is a survey of persistent homology, primarily as it is used in topological data analysis. It includes the theory of persistence modules, as well as stability theorems for persistence barcodes, generalized persistence,…

Algebraic Topology · Mathematics 2020-04-03 Gunnar Carlsson

A central problem in data-driven scientific inquiry is how to interpret structure in noisy, high-dimensional data. Topological data analysis (TDA) provides a solution via persistent homology, which encodes features of interest as…

Algebraic Topology · Mathematics 2026-02-04 Christian Lentz , Gregory Henselman-Petrusek , Lori Ziegelmeier

Statistical analysis on object data presents many challenges. Basic summaries such as means and variances are difficult to compute. We apply ideas from topology to study object data. We present a framework for using persistence landscapes…

Methodology · Statistics 2019-12-12 Vic Patrangenaru , Peter Bubenik , Robert L. Paige , Daniel Osborne

Inferring topological and geometrical information from data can offer an alternative perspective on machine learning problems. Methods from topological data analysis, e.g., persistent homology, enable us to obtain such information,…

Computer Vision and Pattern Recognition · Computer Science 2018-02-19 Christoph Hofer , Roland Kwitt , Marc Niethammer , Andreas Uhl

Topological data analysis combines machine learning with methods from algebraic topology. Persistent homology, a method to characterize topological features occurring in data at multiple scales is of particular interest. A major obstacle to…

Algebraic Topology · Mathematics 2019-04-25 Nello Blaser , Morten Brun

In this paper, we study the persistent homology of the offset filtration of algebraic varieties. We prove the algebraicity of two quantities central to the computation of persistent homology. Moreover, we connect persistent homology and…

Algebraic Geometry · Mathematics 2019-08-21 Emil Horobet , Madeleine Weinstein

Topological methods for data analysis present opportunities for enforcing certain invariances of broad interest in computer vision, including view-point in activity analysis, articulation in shape analysis, and measurement invariance in…

Computer Vision and Pattern Recognition · Computer Science 2018-07-30 Anirudh Som , Kowshik Thopalli , Karthikeyan Natesan Ramamurthy , Vinay Venkataraman , Ankita Shukla , Pavan Turaga

Homology-based invariants can be used to characterize the geometry of datasets and thereby gain some understanding of the processes generating those datasets. In this work we investigate how the geometry of a dataset changes when it is…

Algebraic Topology · Mathematics 2022-03-17 Jens Agerberg , Wojciech Chacholski , Ryan Ramanujam

Identifying molecular signatures from complex disease patients with underlying symptomatic similarities is a significant challenge in the analysis of high dimensional multi-omics data. Topological data analysis (TDA) provides a way of…

Genomics · Quantitative Biology 2024-04-23 Davide Gurnari , Aldo Guzmán-Sáenz , Filippo Utro , Aritra Bose , Saugata Basu , Laxmi Parida

We apply persistent homology, the main method in topological data analysis, to the study of demographic data. Persistence diagrams efficiently summarize information about clusters or peaks in a region's demographic data. To illustrate how…

Algebraic Topology · Mathematics 2023-10-13 Jakini A. Kauba , Thomas Weighill

A central challenge in topological data analysis is the interpretation of barcodes. The classical algebraic-topological approach to interpreting homology classes is to build maps to spaces whose homology carries semantics we understand and…

Algebraic Topology · Mathematics 2023-08-11 Iris H. R. Yoon , Robert Ghrist , Chad Giusti

The theory of multidimensional persistent homology was initially developed in the discrete setting, and involved the study of simplicial complexes filtered through an ordering of the simplices. Later, stability properties of…

Computational Geometry · Computer Science 2013-03-28 Niccolò Cavazza , Marc Ethier , Patrizio Frosini , Tomasz Kaczynski , Claudia Landi

This article aims to study the topological invariant properties encoded in node graph representational embeddings by utilizing tools available in persistent homology. Specifically, given a node embedding representation algorithm, we…

Machine Learning · Computer Science 2021-10-12 Mustafa Hajij , Ghada Zamzmi , Xuanting Cai

Persistent homology is a common technique in topological data analysis providing geometrical and topological information about the sample space. All this information, known as topological features, is summarized in persistence diagrams, and…

Methodology · Statistics 2022-04-05 Asael Fabian Martínez