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Data scarcity and class imbalance are two fundamental challenges in many machine learning applications to healthcare. Breast cancer classification in mammography exemplifies these challenges, with a malignancy rate of around 0.5% in a…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Eric Wu , Kevin Wu , William Lotter

Early detection of malignant lung nodules remains constrained by size and growth based screening criteria, often delaying diagnosis. We present an integrated AI system that jointly performs nodule detection and malignancy assessment…

Mammography is widely recognized as the most reliable technique for early detection of breast cancers. Automated or semi-automated computerized classification schemes can be very useful in assisting radiologists with a second opinion about…

Medical Physics · Physics 2007-05-23 A. Retico , P. Delogu , M. E. Fantacci , P. Kasae

Mammograms are commonly employed in the large scale screening of breast cancer which is primarily characterized by the presence of malignant masses. However, automated image-level detection of malignancy is a challenging task given the…

Computer Vision and Pattern Recognition · Computer Science 2020-04-27 Sarath Chandra K , Arunava Chakravarty , Nirmalya Ghosh , Tandra Sarkar , Ramanathan Sethuraman , Debdoot Sheet

Deep learning-based computer-aided diagnosis has achieved unprecedented performance in breast cancer detection. However, most approaches are computationally intensive, which impedes their broader dissemination in real-world applications. In…

Image and Video Processing · Electrical Eng. & Systems 2022-01-14 Jiaqiao Shi , Aleksandar Vakanski , Min Xian , Jianrui Ding , Chunping Ning

Automatic detection of brain neoplasm in Magnetic Resonance Imaging (MRI) is gaining importance in many medical diagnostic applications. This report presents two improvements for brain neoplasm detection in MRI data: an advanced…

Computer Vision and Pattern Recognition · Computer Science 2021-01-26 Nilanjan Sinhababu , Monalisa Sarma , Debasis Samanta

The past years have seen a considerable increase in cancer cases. However, a cancer diagnosis is often complex and depends on the types of images provided for analysis. It requires highly skilled practitioners but is often time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2022-10-24 Solene Bechelli

Using natural language processing tools, we investigate the differences of recommendations in medical guidelines for the same decision problem -- breast cancer screening. We show that these differences arise from knowledge brought to the…

Information Retrieval · Computer Science 2020-07-22 Hossein Hematialam , Luciana Garbayo , Seethalakshmi Gopalakrishnan , Wlodek Zadrozny

Artificial intelligence is constantly evolving and can provide effective help in all aspects of people's lives. The experiment is mainly to study the use of artificial intelligence in the field of medicine. The purpose of this experiment…

Image and Video Processing · Electrical Eng. & Systems 2023-08-08 Jiuqi Yan

During their formative years, radiology trainees are required to interpret hundreds of mammograms per month, with the objective of becoming apt at discerning the subtle patterns differentiating benign from malignant lesions. Unfortunately,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-26 Cyril Zakka , Ghida Saheb , Elie Najem , Ghina Berjawi

Imaging biomarkers in neuro-oncology are used for diagnosis, prognosis and treatment response monitoring. Magnetic resonance imaging is typically used throughout the patient pathway because routine structural imaging provides detailed…

Quantitative Methods · Quantitative Biology 2019-10-21 Thomas Booth

Interval and large invasive breast cancers, which are associated with worse prognosis than other cancers, are usually detected at a late stage due to false negative assessments of screening mammograms. The missed screening-time detection is…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Moein Sorkhei , Yue Liu , Hossein Azizpour , Edward Azavedo , Karin Dembrower , Dimitra Ntoula , Athanasios Zouzos , Fredrik Strand , Kevin Smith

In the last few years, deep learning classifiers have shown promising results in image-based medical diagnosis. However, interpreting the outputs of these models remains a challenge. In cancer diagnosis, interpretability can be achieved by…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Kangning Liu , Yiqiu Shen , Nan Wu , Jakub Chłędowski , Carlos Fernandez-Granda , Krzysztof J. Geras

Convolutional Neural Networks have shown promising effectiveness in identifying different types of cancer from radiographs. However, the opaque nature of CNNs makes it difficult to fully understand the way they operate, limiting their…

Image and Video Processing · Electrical Eng. & Systems 2026-03-16 Michael Okonoda , Eder Martinez , Abhilekha Dalal , Lior Shamir

Cancer is one of the diseases that kill the most women in the world, with breast cancer being responsible for the highest number of cancer cases and consequently deaths. However, it can be prevented by early detection and, consequently,…

Machine Learning · Computer Science 2025-09-23 João Manoel Herrera Pinheiro , Marcelo Becker

Radiologists interpret mammography exams by jointly analyzing all four views, as correlations among them are crucial for accurate diagnosis. Recent methods employ dedicated fusion blocks to capture such dependencies, but these are often…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Eleonora Lopez , Eleonora Grassucci , Danilo Comminiello

Detection of malignant lesions on mammography images is extremely important for early breast cancer diagnosis. In clinical practice, images are acquired from two different angles, and radiologists can fully utilize information from both…

Image and Video Processing · Electrical Eng. & Systems 2024-04-26 Arina Varlamova , Valery Belotsky , Grigory Novikov , Anton Konushin , Evgeny Sidorov

When we deploy machine learning models in high-stakes medical settings, we must ensure these models make accurate predictions that are consistent with known medical science. Inherently interpretable networks address this need by explaining…

Computer Vision and Pattern Recognition · Computer Science 2021-10-06 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

Early and accurate interpretation of screening mammograms is essential for effective breast cancer detection, yet it remains a complex challenge due to subtle imaging findings and diagnostic ambiguity. Many existing AI approaches fall short…

Image and Video Processing · Electrical Eng. & Systems 2025-07-24 Yalda Zafari , Roaa Elalfy , Mohamed Mabrok , Somaya Al-Maadeed , Tamer Khattab , Essam A. Rashed

Detecting cancers at early stages can dramatically reduce mortality rates. Therefore, practical cancer screening at the population level is needed. Here, we develop a comprehensive detection system to classify all common cancer types. By…

Molecular Networks · Quantitative Biology 2021-03-30 Anyou Wang , Rong Hai , Paul J Rider , Qianchuan He