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High-performance computing (HPC) is reshaping computational drug discovery by enabling large-scale, time-efficient molecular simulations. In this work, we explore HPC-driven pipelines for Alzheimer's disease drug discovery, focusing on…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-03 Paul Ruiz Alliata , Diana Rubaga , Daniel Kumlin , Alberto Puliga

This paper introduces a pipeline to parametrically sample and render multi-task vision datasets from comprehensive 3D scans from the real world. Changing the sampling parameters allows one to "steer" the generated datasets to emphasize…

Computer Vision and Pattern Recognition · Computer Science 2021-10-12 Ainaz Eftekhar , Alexander Sax , Roman Bachmann , Jitendra Malik , Amir Zamir

In this paper, we primarily focus on understanding the data preprocessing pipeline for DNN Training in the public cloud. First, we run experiments to test the performance implications of the two major data preprocessing methods using either…

Machine Learning · Computer Science 2023-04-19 Ping Gong , Yuxin Ma , Cheng Li , Xiaosong Ma , Sam H. Noh

Scale-out parallel processing based on MPI is a 25-year-old standard with at least another decade of preceding history of enabling technologies in the High Performance Computing community. Newer frameworks such as MapReduce, Hadoop, and…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-07-18 Brandon L. Morris , Anthony Skjellum

Nowadays, neural networks act as a synonym for artificial intelligence. Present neural network models, although remarkably powerful, are inefficient both in terms of data and energy. Several alternative forms of neural networks have been…

Neural and Evolutionary Computing · Computer Science 2026-02-27 Mario Franco , Carlos Gershenson

Alchemist is a system that allows Apache Spark to achieve better performance by interfacing with HPC libraries for large-scale distributed computations. In this paper, we highlight some recent developments in Alchemist that are of interest…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-12-02 Kai Rothauge , Haripriya Ayyalasomayajula , Kristyn J. Maschhoff , Michael Ringenburg , Michael W. Mahoney

We introduce BriskStream, an in-memory data stream processing system (DSPSs) specifically designed for modern shared-memory multicore architectures. BriskStream's key contribution is an execution plan optimization paradigm, namely RLAS,…

Databases · Computer Science 2019-04-10 Shuhao Zhang , Jiong He , Amelie Chi Zhou , Bingsheng He

Neuromorphic computing, characterized by its event-driven computation and massive parallelism, is particularly effective for handling data-intensive tasks in low-power environments, such as computing the minimum spanning tree (MST) for…

Emerging Technologies · Computer Science 2025-05-20 Yee Hin Chong , Peng Qu , Yuchen Li , Youhui Zhang

Scaling up deep neural network capacity has been known as an effective approach to improving model quality for several different machine learning tasks. In many cases, increasing model capacity beyond the memory limit of a single…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Yanping Huang , Youlong Cheng , Ankur Bapna , Orhan Firat , Mia Xu Chen , Dehao Chen , HyoukJoong Lee , Jiquan Ngiam , Quoc V. Le , Yonghui Wu , Zhifeng Chen

Approximate Nearest Neighbor Search (ANNS) is a core primitive in modern AI systems, and graph-based methods currently offer the best accuracy-efficiency trade-off at scale. The workload is fundamentally memory-bound: graph traversal…

Hardware Architecture · Computer Science 2026-05-26 Sitian Chen , Yusen Li , Yao Chen , Minwen Deng , Jintao Meng , Amelie Chi Zhou

Neural Architecture Search (NAS) has demonstrated its power on various AI accelerating platforms such as Field Programmable Gate Arrays (FPGAs) and Graphic Processing Units (GPUs). However, it remains an open problem, how to integrate NAS…

Machine Learning · Computer Science 2020-02-12 Lei Yang , Zheyu Yan , Meng Li , Hyoukjun Kwon , Liangzhen Lai , Tushar Krishna , Vikas Chandra , Weiwen Jiang , Yiyu Shi

The training process of Deep Neural Network (DNN) is compute-intensive, often taking days to weeks to train a DNN model. Therefore, parallel execution of DNN training on GPUs is a widely adopted approach to speed up the process nowadays.…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-10-29 Chi-Chung Chen , Chia-Lin Yang , Hsiang-Yun Cheng

Graph Signal Processing (GSP) is a promising framework to analyze multi-dimensional neuroimaging datasets, while taking into account both the spatial and functional dependencies between brain signals. In the present work, we apply…

Computer Vision and Pattern Recognition · Computer Science 2017-08-29 Mathilde Ménoret , Nicolas Farrugia , Bastien Pasdeloup , Vincent Gripon

Over the past decade, the fourth paradigm of data-intensive science rapidly became a major driving concept of multiple application domains encompassing and generating large-scale devices such as light sources and cutting edge telescopes.…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-06-05 Nikolay Malitsky , Ralph Castain , Matt Cowan

Data of the order of terabytes, petabytes, or beyond is known as Big Data. This data cannot be processed using the traditional database software, and hence there comes the need for Big Data Platforms. By combining the capabilities and…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-11-05 Tanuja Patanshetti , Ashish Anil Pawar , Disha Patel , Sanket Thakare

Distributed in-memory data processing engines accelerate iterative applications by caching substantial datasets in memory rather than recomputing them in each iteration. Selecting a suitable cluster size for caching these datasets plays an…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-07-07 Hani Al-Sayeh , Muhammad Attahir Jibril , Bunjamin Memishi , Kai-Uwe Sattler

Approximate computing aims for efficient execution of workflows where an approximate output is sufficient instead of the exact output. The idea behind approximate computing is to compute over a representative sample instead of the entire…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-09-12 Do Le Quoc , Ruichuan Chen , Pramod Bhatotia , Christof Fetze , Volker Hilt , Thorsten Strufe

Apache Flink is an open-source system for scalable processing of batch and streaming data. Flink does not natively support efficient processing of spatial data streams, which is a requirement of many applications dealing with spatial data.…

Databases · Computer Science 2020-08-04 Salman Ahmed Shaikh , Komal Mariam , Hiroyuki Kitagawa , Kyoung-Sook Kim

When processing large medical imaging studies, adopting high performance grid computing resources rapidly becomes important. We recently presented a "medical image processing-as-a-service" grid framework that offers promise in utilizing the…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-12-27 Shunxing Bao , Yuankai Huo , Prasanna Parvathaneni , Andrew J. Plassard , Camilo Bermudez , Yuang Yao , Ilwoo Llyu , Aniruddha Gokhale , Bennett A. Landman