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Background: Seasonal influenza causes a substantial burden on healthcare services over the winter period when these systems are already under pressure. Policies during the COVID-19 pandemic supressed the transmission of season influenza,…

Projection predictive inference is a decision theoretic Bayesian approach that decouples model estimation from decision making. Given a reference model previously built including all variables present in the data, projection predictive…

Methodology · Statistics 2020-10-15 Alejandro Catalina , Paul-Christian Bürkner , Aki Vehtari

Recommendation systems and computing advertisements have gradually entered the field of academic research from the field of commercial applications. Click-through rate prediction is one of the core research issues because the prediction…

Machine Learning · Computer Science 2019-02-26 Li Zhang , Weichen Shen , Shijian Li , Gang Pan

Sparse regularized regression methods are now widely used in genome-wide association studies (GWAS) to address the multiple testing burden that limits discovery of potentially important predictors. Linear mixed models (LMMs) have become an…

Methodology · Statistics 2022-06-27 Julien St-Pierre , Karim Oualkacha , Sahir Rai Bhatnagar

Alzheimer's Disease Analysis Model (ADAM) is a multi-agent reasoning large language model (LLM) framework designed to integrate and analyze multimodal data, including microbiome profiles, clinical datasets, and external knowledge bases, to…

Artificial Intelligence · Computer Science 2025-08-22 Ziyuan Huang , Vishaldeep Kaur Sekhon , Roozbeh Sadeghian , Maria L. Vaida , Cynthia Jo , Doyle Ward , Vanni Bucci , John P. Haran

Generalized Additive Models (GAMs) have recently experienced a resurgence in popularity due to their interpretability, which arises from expressing the target value as a sum of non-linear transformations of the features. Despite the current…

The cgam package contains routines to fit the generalized additive model where the components may be modeled with shape and smoothness assumptions. The main routine is cgam and nineteen symbolic routines are provided to indicate the…

Applications · Statistics 2018-12-20 Xiyue Liao , Mary C. Meyer

Databases in domains such as healthcare are routinely released to the public in aggregated form. Unfortunately, naive modeling with aggregated data may significantly diminish the accuracy of inferences at the individual level. This paper…

Machine Learning · Statistics 2016-05-17 Avradeep Bhowmik , Joydeep Ghosh , Oluwasanmi Koyejo

As an emerging interpretable technique, Generalized Additive Models (GAMs) adopt neural networks to individually learn non-linear functions for each feature, which are then combined through a linear model for final predictions. Although…

Machine Learning · Computer Science 2024-08-01 Viet Duong , Qiong Wu , Zhengyi Zhou , Hongjue Zhao , Chenxiang Luo , Eric Zavesky , Huaxiu Yao , Huajie Shao

Inevitable domain and task discrepancies in real-world scenarios can impair the generalization performance of the pre-trained deep models for medical data. Therefore, we audaciously propose that we should build a general-purpose medical AI…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Huahui Yi , Ziyuan Qin , Qicheng Lao , Wei Xu , Zekun Jiang , Dequan Wang , Shaoting Zhang , Kang Li

Neural Additive Models (NAMs) have recently demonstrated promising predictive performance while maintaining interpretability. However, their capacity is limited to capturing only first-order feature interactions, which restricts their…

Machine Learning · Computer Science 2025-11-17 Minkyu Kim , Hyun-Soo Choi , Jinho Kim

Background: This study aims to develop and validate federated learning models for predicting major postoperative complications and mortality using a large multicenter dataset from the OneFlorida Data Trust. We hypothesize that federated…

This work presents a formalism to improve the predictive accuracy of physical models by learning generalizable augmentations from sparse data. Building on recent advances in data-driven turbulence modeling, the present approach, referred to…

Fluid Dynamics · Physics 2021-07-28 Vishal Srivastava , Karthik Duraisamy

High-cardinality categorical features are pervasive in actuarial data (e.g. occupation in commercial property insurance). Standard categorical encoding methods like one-hot encoding are inadequate in these settings. In this work, we present…

Machine Learning · Statistics 2024-11-20 Benjamin Avanzi , Greg Taylor , Melantha Wang , Bernard Wong

Large Language Models have advanced clinical text classification, but their opaque predictions remain a critical barrier to practical adoption in research and clinical settings where investigators and physicians need to understand which…

Computation and Language · Computer Science 2025-11-18 Karthikeyan K , Raghuveer Thirukovalluru , David Carlson

A barrier to the wider adoption of neural networks is their lack of interpretability. While local explanation methods exist for one prediction, most global attributions still reduce neural network decisions to a single set of features. In…

Machine Learning · Computer Science 2019-02-08 Mark Ibrahim , Melissa Louie , Ceena Modarres , John Paisley

With increasing interest in applying machine learning to develop healthcare solutions, there is a desire to create interpretable deep learning models for survival analysis. In this paper, we extend the Neural Additive Model (NAM) by…

Machine Learning · Computer Science 2022-11-18 Matthew Peroni , Marharyta Kurban , Sun Young Yang , Young Sun Kim , Hae Yeon Kang , Ji Hyun Song

Generalized latent factor analysis not only provides a useful latent embedding approach in statistics and machine learning, but also serves as a widely used tool across various scientific fields, such as psychometrics, econometrics, and…

Methodology · Statistics 2025-08-11 Chengyu Cui , Gongjun Xu

Reinforcement learning (RL) is central to post-training, particularly for agentic models that require specialized reasoning behaviors. In this setting, model merging offers a practical mechanism for integrating multiple RL-trained agents…

Machine Learning · Computer Science 2026-01-21 Xiangchi Yuan , Dachuan Shi , Chunhui Zhang , Zheyuan Liu , Shenglong Yao , Soroush Vosoughi , Wenke Lee

Factorization machines (FM) are a popular model class to learn pairwise interactions by a low-rank approximation. Different from existing FM-based approaches which use a fixed rank for all features, this paper proposes a Rank-Aware FM…

Machine Learning · Computer Science 2019-05-21 Xiaoshuang Chen , Yin Zheng , Jiaxing Wang , Wenye Ma , Junzhou Huang