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Nodule malignancy assessment is a complex, time-consuming and error-prone task. Current clinical practice requires measuring changes in size and density of the nodule at different time-points. State of the art solutions rely on 3D…

Image and Video Processing · Electrical Eng. & Systems 2020-05-27 Xavier Rafael-Palou , Anton Aubanell , Ilaria Bonavita , Mario Ceresa , Gemma Piella , Vicent Ribas , Miguel A. González Ballester

Convolutional Neural Networks (CNNs) require a large amount of annotated data to learn from, which is often difficult to obtain in the medical domain. In this paper we show that the sample complexity of CNNs can be significantly improved by…

Machine Learning · Computer Science 2019-04-23 Marysia Winkels , Taco S. Cohen

Deep learning, as a promising new area of machine learning, has attracted a rapidly increasing attention in the field of medical imaging. Compared to the conventional machine learning methods, deep learning requires no hand-tuned feature…

Quantitative Methods · Quantitative Biology 2016-11-29 He Yang , Hengyong Yu , Ge Wang

A computer-aided detection (CAD) system for the identification of pulmonary nodules in low-dose multi-detector computed-tomography (CT) images has been developed in the framework of the MAGIC-5 Italian project. One of the main goals of this…

Lung cancer is a global and dangerous disease, and its early detection is crucial to reducing the risks of mortality. In this regard, it has been of great interest in developing a computer-aided system for pulmonary nodules detection as…

Computer Vision and Pattern Recognition · Computer Science 2018-07-30 Bum-Chae Kim , Jun-Sik Choi , Heung-Il Suk

Lung Cancer is the most common cause of cancer-related death worldwide. Early and automatic diagnosis of Solitary Pulmonary Nodules (SPN) in Computer Tomography (CT) chest scans can provide early treatment as well as doctor liberation from…

Image and Video Processing · Electrical Eng. & Systems 2020-03-31 Ioannis D. Apostolopoulos

Automated detection and segmentation of pulmonary nodules on lung computed tomography (CT) scans can facilitate early lung cancer diagnosis. Existing supervised approaches for automated nodule segmentation on CT scans require voxel-based…

Computer Vision and Pattern Recognition · Computer Science 2018-02-26 Xinyang Feng , Jie Yang , Andrew F. Laine , Elsa D. Angelini

Computer Aided Diagnosis has emerged as an indispensible technique for validating the opinion of radiologists in CT interpretation. This paper presents a deep 3D Convolutional Neural Network (CNN) architecture for automated CT scan-based…

Image and Video Processing · Electrical Eng. & Systems 2019-06-05 Sumita Mishra , Naresh Kumar Chaudhary , Pallavi Asthana , Anil Kumar

Pulmonary nodules are an early sign of lung cancer, and detecting them early is vital for improving patient survival rates. Most current methods use only single Computed Tomography (CT) images to assess nodule malignancy. However, doctors…

Image and Video Processing · Electrical Eng. & Systems 2025-01-29 Yin Shen , Zhaojie Fang , Ke Zhuang , Guanyu Zhou , Xiao Yu , Yucheng Zhao , Yuan Tian , Ruiquan Ge , Changmiao Wang , Xiaopeng Fan , Ahmed Elazab

Early detection of lung cancer is an effective way to improve the survival rate of patients. It is a critical step to have accurate detection of lung nodules in computed tomography (CT) images for the diagnosis of lung cancer. However, due…

Computer Vision and Pattern Recognition · Computer Science 2019-05-10 Haichao Cao , Hong Liu , Enmin Song , Guangzhi Ma , Xiangyang Xu , Renchao Jin , Tengying Liu , Chih-Cheng Hung

Lung cancer is a leading cause of cancer-related deaths worldwide, and early detection is crucial for improving patient outcomes. Nevertheless, early diagnosis of cancer is a major challenge, particularly in low-resource settings where…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Samiul Based Shuvo , Tasnia Binte Mamun

This paper proposes novel end-to-end framework for detecting suspicious pulmonary nodules in chest CT scans. The method core idea is a new nodule segmentation architecture with a model-based feature projection block on three-dimensional…

Image and Video Processing · Electrical Eng. & Systems 2021-06-11 Ivan Drokin , Elena Ericheva

Purpose: The lung nodules localization in CT scan images is the most difficult task due to the complexity of the arbitrariness of shape, size, and texture of lung nodules. This is a challenge to be faced when coming to developing different…

Image and Video Processing · Electrical Eng. & Systems 2023-01-06 Haytham Al Ewaidat , Youness El Brag

To predict lung nodule malignancy with a high sensitivity and specificity, we propose a fusion algorithm that combines handcrafted features (HF) into the features learned at the output layer of a 3D deep convolutional neural network (CNN).…

Computer Vision and Pattern Recognition · Computer Science 2020-01-08 Shulong Li , Panpan Xu , Bin Li , Liyuan Chen , Zhiguo Zhou , Hongxia Hao , Yingying Duan , Michael Folkert , Jianhua Ma , Steve Jiang , Jing Wang

Lung cancer is a primary contributor to cancer-related mortality globally, highlighting the necessity for precise early detection of pulmonary nodules through low-dose CT (LDCT) imaging. Deep learning methods have improved nodule detection…

Quantitative Methods · Quantitative Biology 2025-12-10 Fateme Mobini , Mohammad Reza Hedyehzadeh , Mahdi Yousefi

Pulmonary cancer is one of the most commonly diagnosed and fatal cancers and is often diagnosed by incidental findings on computed tomography. Automated pulmonary nodule detection is an essential part of computer-aided diagnosis, which is…

Image and Video Processing · Electrical Eng. & Systems 2021-10-26 Jiahua Xu , Philipp Ernst , Tung Lung Liu , Andreas Nürnberger

Early detection of lung cancer has been proven to decrease mortality significantly. A recent development in computed tomography (CT), spectral CT, can potentially improve diagnostic accuracy, as it yields more information per scan than…

Computer Vision and Pattern Recognition · Computer Science 2020-07-01 Linde S. Hesse , Pim A. de Jong , Josien P. W. Pluim , Veronika Cheplygina

Lung cancer remains one of the leading causes of cancer-related mortality worldwide, with early and accurate diagnosis playing a pivotal role in improving patient outcomes. Automated detection of pulmonary nodules in computed tomography…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Abhinav Roy , Bhavesh Gyanchandani , Aditya Oza

In the first step, a pre-trained model (YOLO) was used to detect all suspicious nod-ules. The YOLO model was re-trained using 397 CT images to detect the entire nodule in CT images. To maximize the sensitivity of the model, a confidence…

Medical Physics · Physics 2022-12-20 Yashar Ahmadyar Razlighi , Alireza Kamali-Asl , Hossein Arabi

Lung nodule detection from 3D Computed Tomography scans plays a vital role in efficient lung cancer screening. Despite the SOTA performance obtained by recent anchor-based detectors using CNNs for this task, they require predetermined…

Computer Vision and Pattern Recognition · Computer Science 2022-01-07 Xiangde Luo , Tao Song , Guotai Wang , Jieneng Chen , Yinan Chen , Kang Li , Dimitris N. Metaxas , Shaoting Zhang