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Cardiovascular disease (CVD) is the global leading cause of death. A strong risk factor for CVD events is the amount of coronary artery calcium (CAC). To meet demands of the increasing interest in quantification of CAC, i.e. coronary…

Computer Vision and Pattern Recognition · Computer Science 2021-09-09 Bob D. de Vos , Jelmer M. Wolterink , Tim Leiner , Pim A. de Jong , Nikolas Lessmann , Ivana Isgum

Coronary artery calcium (CAC) is biomarker of advanced subclinical coronary artery disease and predicts myocardial infarction and death prior to age 60 years. The slice-wise manual delineation has been regarded as the gold standard of…

Computer Vision and Pattern Recognition · Computer Science 2018-11-13 Yuankai Huo , James G. Terry , Jiachen Wang , Vishwesh Nath , Camilo Bermudez , Shunxing Bao , Prasanna Parvathaneni , J. Jeffery Carr , Bennett A. Landman

Every year, thousands of innocent people die due to heart attacks. Often undiagnosed heart attacks can hit people by surprise since many current medical plans don't cover the costs to require the searching of calcification on these scans.…

Image and Video Processing · Electrical Eng. & Systems 2022-09-23 Sanskriti Singh

Coronary artery calcium (CAC) burden quantified in low-dose chest CT is a predictor of cardiovascular events. We propose an automatic method for CAC quantification, circumventing intermediate segmentation of CAC. The method determines a…

Computer Vision and Pattern Recognition · Computer Science 2017-12-11 Bob D. de Vos , Nikolas Lessmann , Pim A. de Jong , Max A. Viergever , Ivana Isgum

Coronary artery calcium (CAC) is a significant marker of atherosclerosis and cardiovascular events. In this work we present a system for the automatic quantification of calcium score in ECG-triggered non-contrast enhanced cardiac computed…

Computer Vision and Pattern Recognition · Computer Science 2017-10-10 G. Santini , D. Della Latta , N. Martini , G. Valvano , A. Gori , A. Ripoli , C. L. Susini , L. Landini , D. Chiappino

Cardiovascular disease causes high rates of mortality worldwide. Coronary artery calcium (CAC) scoring is a powerful tool to stratify the risk of atherosclerotic cardiovascular disease. Current scoring practices require time-intensive…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Lachlan Nguyen , Aidan Cousins , Arcot Sowmya , Hugh Dixson , Sonit Singh

Vessel stenosis is a major risk factor in cardiovascular diseases (CVD). To analyze the degree of vessel stenosis for supporting the treatment management, extraction of coronary artery area from Computed Tomographic Angiography (CTA) is…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Yo-Chuan Chen , Yi-Chen Lin , Ching-Ping Wang , Chia-Yen Lee , Wen-Jeng Lee , Tzung-Dau Wang , Chung-Ming Chen

Early detection of coronary artery disease (CAD) is critical for reducing mortality and improving patient treatment planning. While angiographic image analysis from X-rays is a common and cost-effective method for identifying cardiac…

Computer Vision and Pattern Recognition · Computer Science 2026-03-04 Alvee Hassan , Rusab Sarmun , Muhammad E. H. Chowdhury , M Murugappan , Abdulrahman Alqahtani , Balamurugan Balusamy , Sohaib Bassam Zoghoul

Coronary artery disease (CAD) is a leading cause of cardiovascular-related mortality, and accurate stenosis detection is crucial for effective clinical decision-making. Coronary angiography remains the gold standard for diagnosing CAD, but…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Baixiang Huang , Yu Luo , Guangyu Wei , Songyan He , Yushuang Shao , Xueying Zeng

Coronary artery calcification (CAC) is a strong and independent predictor of cardiovascular disease (CVD). However, manual assessment of CAC often requires radiological expertise, time, and invasive imaging techniques. The purpose of this…

Computer Vision and Pattern Recognition · Computer Science 2024-02-16 Andrew M. Nguyen , Jianfei Liu , Tejas Sudharshan Mathai , Peter C. Grayson , Ronald M. Summers

Coronary artery calcification (CAC) is a strong predictor of cardiovascular risk but remains underutilized in clinical routine thoracic imaging due to the need for dedicated imaging protocols and manual annotation. We present DeepCAC2, a…

Image and Video Processing · Electrical Eng. & Systems 2026-03-27 Leonard Nürnberg , Simon Bernatz , Borek Foldyna , Michael T. Lu , Andrey Fedorov , Hugo JWL Aerts

Coronary angiography is considered to be a safe tool for the evaluation of coronary artery disease and perform in approximately 12 million patients each year worldwide. [1] In most cases, angiograms are manually analyzed by a cardiologist.…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Stanislav Filippov , Arsenii Moiseev , Andronenko Andrey

Early detection and diagnosis of coronary artery disease (CAD) could save lives and reduce healthcare costs. The current clinical practice is to perform CAD diagnosis through analysing medical images from computed tomography coronary…

Cardiovascular disease remains a significant problem in modern society. Among non-invasive techniques, the electrocardiogram (ECG) is one of the most reliable methods for detecting abnormalities in cardiac activities. However, ECG…

Signal Processing · Electrical Eng. & Systems 2023-03-22 Huy Pham , Konstantin Egorov , Alexey Kazakov , Semen Budennyy

Coronary calcium causes beam hardening and blooming artifacts on cardiac computed tomography angiography (CTA) images, which lead to overestimation of lumen stenosis and reduction of diagnostic specificity. To properly remove coronary…

Computer Vision and Pattern Recognition · Computer Science 2018-03-02 Siming Yan , Feng Shi , Yuhua Chen , Damini Dey , Sang-Eun Lee , Hyuk-Jae Chang , Debiao Li , Yibin Xie

Coronary artery calcification (CAC) is a strong predictor of cardiovascular events, with CT-based Agatston scoring widely regarded as the clinical gold standard. However, CT is costly and impractical for large-scale screening, while chest…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Dylan Saeed , Ramtin Gharleghi , Susann Beier , Sonit Singh

Cardiovascular Diseases (CVDs) are the leading cause of death worldwide, taking 17.9 million lives annually. Abdominal Aortic Calcification (AAC) is an established marker for CVD, which can be observed in lateral view Vertebral Fracture…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Zaid Ilyas , Afsah Saleem , David Suter , Siobhan Reid , John Schousboe , William Leslie , Joshua Lewis , Syed Zulqarnain Gilani

Heavy smokers undergoing screening with low-dose chest CT are affected by cardiovascular disease as much as by lung cancer. Low-dose chest CT scans acquired in screening enable quantification of atherosclerotic calcifications and thus…

Computer Vision and Pattern Recognition · Computer Science 2018-02-06 Nikolas Lessmann , Bram van Ginneken , Majd Zreik , Pim A. de Jong , Bob D. de Vos , Max A. Viergever , Ivana Išgum

Coronary artery calcium (CAC) is highly predictive of cardiovascular events. While millions of chest CT scans are performed annually in the United States, CAC is not routinely quantified from scans done for non-cardiac purposes. A deep…

Aims. To develop a deep-learning based system for recognition of subclinical atherosclerosis on a plain frontal chest x-ray. Methods and Results. A deep-learning algorithm to predict coronary artery calcium (CAC) score (the AI-CAC model)…

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