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Dynamical system models of complex biochemical reaction networks are usually high-dimensional, nonlinear, and contain many unknown parameters. In some cases the reaction network structure dictates that positive equilibria must be unique for…

Dynamical Systems · Mathematics 2008-09-09 Gheorghe Craciun , J. William Helton , Ruth J. Williams

A method for integrating the chemical equations associated with nuclear combustion at high temperature is presented and extensively checked. Following the idea of E. M\"uller, the feedback between nuclear rates and temperature was taken…

Astrophysics · Physics 2007-05-23 Ruben M. Cabezon Gomez , Domingo Garcia-Senz , Eduardo Bravo

This study addresses the vital role of data analytics in monitoring fertiliser applications in crop cultivation. Inaccurate fertiliser application decisions can lead to costly consequences, hinder food production, and cause environmental…

Machine Learning · Computer Science 2023-10-19 Usama Ikhlaq , Tahar Kechadi

A detailed understanding of biochemical networks at the molecular level is essential for studying complex cellular processes. In this paper, we provide a comprehensive description of biochemical networks by considering individual atoms and…

Molecular Networks · Quantitative Biology 2025-04-08 Hadjar Rahou , Hulda S. Haraldsdottir , Filippo Martinelli , Ines Thiele , Ronan M. T. Fleming

Regular nutrient intake monitoring in hospitalised patients plays a critical role in reducing the risk of disease-related malnutrition (DRM). Although several methods to estimate nutrient intake have been developed, there is still a clear…

Computer Vision and Pattern Recognition · Computer Science 2019-06-13 Ya Lu , Thomai Stathopoulou , Maria F. Vasiloglou , Stergios Christodoulidis , Beat Blum , Thomas Walser , Vinzenz Meier , Zeno Stanga , Stavroula G. Mougiakakou

Although ordinary differential equations (ODEs) provide insights for designing network architectures, its relationship with the non-residual convolutional neural networks (CNNs) is still unclear. In this paper, we present a novel ODE model…

Machine Learning · Statistics 2020-08-18 Zonghan Yang , Yang Liu , Chenglong Bao , Zuoqiang Shi

We define a subclass of Chemical Reaction Networks called Post-Translational Modification systems. Important biological examples of such systems include MAPK cascades and two-component systems which are well-studied experimentally as well…

Molecular Networks · Quantitative Biology 2011-07-19 Elisenda Feliu , Carsten Wiuf

Stochastic reaction networks are mathematical models with a wide range of applications in biochemistry, ecology, and epidemiology, and are often complex to analyze. Except for some special cases, it is generally difficult to predict how the…

Probability · Mathematics 2026-04-02 Daniele Cappelletti , Giulio Cuniberti , Paola Siri

The inverse problem of supervised reconstruction of depth-variable (time-dependent) parameters in a neural ordinary differential equation (NODE) is considered, that means finding the weights of a residual network with time continuous…

Machine Learning · Computer Science 2022-02-14 George Baravdish , Gabriel Eilertsen , Rym Jaroudi , B. Tomas Johansson , Lukáš Malý , Jonas Unger

Application of nonlinearity continuation method to numerical solution of steady-state groundwater flow in variably saturated conditions is presented. In order to solve the system of nonlinear equations obtained by finite volume…

Numerical Analysis · Mathematics 2020-08-04 Denis Anuprienko , Ivan Kapyrin

We introduce OS-net (Orbitally Stable neural NETworks), a new family of neural network architectures specifically designed for periodic dynamical data. OS-net is a special case of Neural Ordinary Differential Equations (NODEs) and takes…

Dynamical Systems · Mathematics 2023-09-27 Marieme Ngom , Carlo Graziani

Living cells display a remarkable capacity to compartmentalize their functional biochemistry. A particularly fascinating example is the cell nucleus. Exchange of macromolecules between the nucleus and the surrounding cytoplasm does not…

Subcellular Processes · Quantitative Biology 2017-04-19 Ching-Hao Wang , Pankaj Mehta , Michael Elbaum

Increasing the layer number of on-chip photonic neural networks (PNNs) is essential to improve its model performance. However, the successively cascading of network hidden layers results in larger integrated photonic chip areas. To address…

Machine Learning · Computer Science 2023-02-08 Yun Zhao , Hang Chen , Min Lin , Haiou Zhang , Tao Yan , Xing Lin , Ruqi Huang , Qionghai Dai

The continuous dynamics of natural systems has been effectively modelled using Neural Ordinary Differential Equations (Neural ODEs). However, for accurate and meaningful predictions, it is crucial that the models follow the underlying rules…

Machine Learning · Computer Science 2024-03-06 C. Coelho , M. Fernanda P. Costa , L. L. Ferrás

This paper presents a novel framework for the modeling of biological networks. It makes use of recent tools analyzing the robust satisfaction of properties of (hybrid) dynamical systems. The main challenge of this approach as applied to…

Computational Engineering, Finance, and Science · Computer Science 2012-08-22 Nicolas Mobilia , Alexandre Donzé , Jean Marc Moulis , Éric Fanchon

Analyzing qualitative behaviors of biochemical reactions using its associated network structure has proven useful in diverse branches of biology. As an extension of our previous work, we introduce a graph-based framework to calculate steady…

Classical Analysis and ODEs · Mathematics 2014-04-28 Inom Mirzaev , David Matthew Bortz

The detailed balance property is a fundamental property that must be satisfied in all the macroscopic systems with a well defined temperature at each point. On the other hand, many biochemical networks work in non-equilibrium conditions and…

Classical Analysis and ODEs · Mathematics 2025-02-10 E. Franco , J. J. L. Velázquez

Model reduction for fluid flow simulation continues to be of great interest across a number of scientific and engineering fields. Here, we explore the use of Neural Ordinary Differential Equations, a recently introduced family of…

Machine Learning · Computer Science 2021-04-30 Sourav Dutta , Peter Rivera-Casillas , Matthew W. Farthing

In this study, we investigate the complexity of two-phase flow (air/water) in a heterogeneous soil sample by using complex network theory, where the supposed porous media is non-deformable media, under the time-dependent gas pressure. Based…

Computational Engineering, Finance, and Science · Computer Science 2010-08-11 Hamed. O. Ghaffari , Mamdou Fall , Erman. Evgin

We identify the thermodynamic conditions necessary to observe indefinite growth in homogeneous open chemical reaction networks (CRNs) satisfying mass action kinetics. We also characterize the thermodynamic efficiency of growth by…

Molecular Networks · Quantitative Biology 2024-12-05 Shesha Gopal Marehalli Srinivas , Francesco Avanzini , Massimiliano Esposito