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Histopathological analysis is the present gold standard for precancerous lesion diagnosis. The goal of automated histopathological classification from digital images requires supervised training, which requires a large number of expert…

Image and Video Processing · Electrical Eng. & Systems 2021-11-15 Yuan Xue , Jiarong Ye , Qianying Zhou , Rodney Long , Sameer Antani , Zhiyun Xue , Carl Cornwell , Richard Zaino , Keith Cheng , Xiaolei Huang

Supervised training of an automated medical image analysis system often requires a large amount of expert annotations that are hard to collect. Moreover, the proportions of data available across different classes may be highly imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Yuan Xue , Jiarong Ye , Rodney Long , Sameer Antani , Zhiyun Xue , Xiaolei Huang

Cervical cancer is one of the deadliest cancers affecting women globally. Cervical intraepithelial neoplasia (CIN) assessment using histopathological examination of cervical biopsy slides is subject to interobserver variability. Automated…

Image and Video Processing · Electrical Eng. & Systems 2020-07-23 Sudhir Sornapudi , R. Joe Stanley , William V. Stoecker , Rodney Long , Zhiyun Xue , Rosemary Zuna , Shelliane R. Frazier , Sameer Antani

Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Leire Benito-Del-Valle , Aitor Alvarez-Gila , Itziar Eguskiza , Cristina L. Saratxaga

Deep learning techniques have become widely utilized in histopathology image classification due to their superior performance. However, this success heavily relies on the availability of substantial labeled data, which necessitates…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Meng Li , Chaoyi Li , Can Peng , Brian C. Lovell

Automatic thin-prep cytologic test (TCT) screening can assist pathologists in finding cervical abnormality towards accurate and efficient cervical cancer diagnosis. Current automatic TCT screening systems mostly involve abnormal cervical…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Zhenrong Shen , Manman Fei , Xin Wang , Jiangdong Cai , Sheng Wang , Lichi Zhang , Qian Wang

Deep learning methods, and in particular convolutional neural networks (CNNs), have led to an enormous breakthrough in a wide range of computer vision tasks, primarily by using large-scale annotated datasets. However, obtaining such…

Computer Vision and Pattern Recognition · Computer Science 2019-01-23 Maayan Frid-Adar , Idit Diamant , Eyal Klang , Michal Amitai , Jacob Goldberger , Hayit Greenspan

Automatic examination of thin-prep cytologic test (TCT) slides can assist pathologists in finding cervical abnormality for accurate and efficient cancer screening. Current solutions mostly need to localize suspicious cells and classify…

Computer Vision and Pattern Recognition · Computer Science 2023-07-13 Zhenrong Shen , Maosong Cao , Sheng Wang , Lichi Zhang , Qian Wang

Publicly available diabetic retinopathy (DR) datasets are imbalanced, containing limited numbers of images with DR. This imbalance contributes to overfitting when training machine learning classifiers. The impact of this imbalance is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-31 Cristina-Madalina Dragan , Muhammad Muneeb Saad , Mubashir Husain Rehmani , Ruairi O'Reilly

Despite the recent success in applying supervised deep learning to medical imaging tasks, the problem of obtaining large and diverse expert-annotated datasets required for the development of high performant models remains particularly…

Computer Vision and Pattern Recognition · Computer Science 2019-11-21 Amirata Ghorbani , Vivek Natarajan , David Coz , Yuan Liu

Fine-grained classification of cervical cells into different abnormality levels is of great clinical importance but remains very challenging. Contrary to traditional classification methods that rely on hand-crafted or engineered features,…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Haoming Lin , Yuyang Hu , Siping Chen , Jianhua Yao , Ling Zhang

One of the most challenging aspects of medical image analysis is the lack of a high quantity of annotated data. This makes it difficult for deep learning algorithms to perform well due to a lack of variations in the input space. While…

Computer Vision and Pattern Recognition · Computer Science 2020-03-13 Soumyajyoti Dey , Soham Das , Swarnendu Ghosh , Shyamali Mitra , Sukanta Chakrabarty , Nibaran Das

Histology imaging is an essential diagnosis method to finalize the grade and stage of cancer of different tissues, especially for breast cancer diagnosis. Specialists often disagree on the final diagnosis on biopsy tissue due to the complex…

Computer Vision and Pattern Recognition · Computer Science 2019-09-17 Yongxiang Huang , Albert Chi-shing Chung

Artificial intelligence methods including deep neural networks (DNN) can provide rapid molecular classification of tumors from routine histology with accuracy that matches or exceeds human pathologists. Discerning how neural networks make…

Generative models have been applied in the medical imaging domain for various image recognition and synthesis tasks. However, a more controllable and interpretable image synthesis model is still lacking yet necessary for important…

Image and Video Processing · Electrical Eng. & Systems 2021-11-15 Jiarong Ye , Yuan Xue , Peter Liu , Richard Zaino , Keith Cheng , Xiaolei Huang

Data augmentation can effectively resolve a scarcity of images when training machine-learning algorithms. It can make them more robust to unseen images. We present a lesion conditional Generative Adversarial Network LcGAN to generate…

Image and Video Processing · Electrical Eng. & Systems 2020-08-10 Manohar Karki , Junghwan Cho , Seokhwan Ko

Deep learning approaches to breast cancer detection in mammograms have recently shown promising results. However, such models are constrained by the limited size of publicly available mammography datasets, in large part due to privacy…

Computer Vision and Pattern Recognition · Computer Science 2018-08-27 Eric Wu , Kevin Wu , David Cox , William Lotter

Histopathology image synthesis aims to address the data shortage issue in training deep learning approaches for accurate cancer detection. However, existing methods struggle to produce realistic images that have accurate nuclei boundaries…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Sujata Butte , Haotian Wang , Aleksandar Vakanski , Min Xian

In biomedical image analysis, data imbalance is common across several imaging modalities. Data augmentation is one of the key solutions in addressing this limitation. Generative Adversarial Networks (GANs) are increasingly being relied upon…

Image and Video Processing · Electrical Eng. & Systems 2023-08-08 Muhammad Muneeb Saad , Mubashir Husain Rehmani , Ruairi O'Reilly

In the realm of dermatological diagnoses, where the analysis of dermatoscopic and microscopic skin lesion images is pivotal for the accurate and early detection of various medical conditions, the costs associated with creating diverse and…

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