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Binary fluid mixtures are examples of complex fluids whose microstructure and flow are strongly coupled. For pairs of simple fluids, the microstructure consists of droplets or bicontinuous demixed domains and the physics is controlled by…

Soft Condensed Matter · Physics 2018-06-05 Michael E. Cates , Elsen Tjhung

A key process in the life of any multicellular organism is its development from a single egg into a full grown adult. The first step in this process often consists of forming a tissue layer out of randomly placed cells on the surface of the…

Over the last two decades, scientific literature has been blooming with various means of simulating epithelial cell colonies. Each of these simulations can be separated by their respective efficiency (expressed in terms of consumed…

Computational Physics · Physics 2022-12-20 Kevin Höllring , Ana-Sunčana Smith

All cells must keep time to consistently perform vital biological functions. To that end, the coupling and interrelatedness of diverse subsecond events in the complex cellular environment, such as protein folding or translation rates,…

Subcellular Processes · Quantitative Biology 2012-10-02 Sepehr Ehsani

Biological cells can actively tune their intracellular architecture according to their overall shape. Here we explore the rheological implication of such coupling in a minimal model of a dense cellular material where each cell exerts an…

Soft Condensed Matter · Physics 2022-04-13 Shao-Zhen Lin , Matthias Merkel , Jean-François Rupprecht

The physics of liquids in porous media gives rise to many interesting phenomena, including imbibition where a viscous fluid displaces a less viscous one. Here we discuss the theoretical and experimental progress made in recent years in this…

Materials Science · Physics 2015-06-24 Mikko Alava , Martin Dubé , Martin Rost

Cytoplasmic streaming, the persistent flow of fluid inside a cell, induces intracellular transport, which plays a key role in fundamental biological processes. In meiosis II mouse oocytes (developing egg cells) awaiting fertilisation, the…

Biological Physics · Physics 2024-10-18 Weida Liao , Eric Lauga

The applicability of computational and dynamical systems models to organisms is scrutinized, using examples from developmental biology and cognition. Developmental morphogenesis is dependent on the inherent material properties of developing…

Neurons and Cognition · Quantitative Biology 2023-10-24 Stuart A. Newman

Several micro-organisms, such as bacteria, algae, or spermatozoa, use flagella or cilia to swim in a fluid, while many other micro-organisms instead use ample shape deformation, described as amoeboid, to propel themselves by either crawling…

Biological Physics · Physics 2016-09-19 Hao Wu , A. Farutin , W. -F. Hu , M. Thiébaud , S. Rafaï , P. Peyla , M. -C. Lai , C. Misbah

We numerically study the dynamic behavior under a symmetric shear flow of selected examples of concentrated phase emulsions with multi-core morphology confined within a microfluidic channel. A variety of new nonequilibrium steady states is…

Soft Condensed Matter · Physics 2020-12-07 A. Tiribocchi , A. Montessori , F. Bonaccorso , M. Lauricella , S. Succi

Microscale fluid flows generated by ensembles of beating eukaryotic flagella are crucial to fundamental processes such as development, motility and sensing. Despite significant experimental and theoretical progress, the underlying physical…

Soft Condensed Matter · Physics 2014-03-11 Douglas R. Brumley , Kirsty Y. Wan , Marco Polin , Raymond E. Goldstein

Organisms often swim through fluids that are spatially inhomogeneous. If the fluids are polymeric, gradients in polymer concentration may lead to gradients in both fluid viscosity and elasticity. In this letter, we present theoretical…

Fluid Dynamics · Physics 2024-11-08 Vaseem A. Shaik , Jiahao Gong , Gwynn J. Elfring

Bacterial cellulose is an important class of biomaterials which can be grown in well-controlled laboratory and industrial conditions. The cellulose structure is affected by several biological, chemical and environmental factors, including…

Biological Physics · Physics 2021-07-28 Sung-Ha Hong , Jia Yang , Mahdi Davoodianidalik , Horst Punzmann , Michael Shats , Hua Xia

Biological genotypes do not code directly for phenotypes; developmental physiology is the control layer that separates genomes from capacities ascertained by selection. A key aspect is competency, as cells are not a passive material but…

Populations and Evolution · Quantitative Biology 2022-08-01 Lakshwin Shreesha , Michael Levin

The microvascular networks in the body of vertebrates consist of the smallest vessels such as arterioles, capillaries, and venules. The flow of RBCs through these networks ensures the gas exchange in as well as the transport of nutrients to…

Biological Physics · Physics 2021-02-26 A. Kihm , S. Quint , M. W. Laschke , M. D. Menger , T. John , L. Kaestner , C. Wagner

Different subsystems of organisms adapt over many time scales, such as rapid changes in the nervous system (learning), slower morphological and neurological change over the lifetime of the organism (postnatal development), and change over…

Neural and Evolutionary Computing · Computer Science 2017-07-28 Sam Kriegman , Nick Cheney , Francesco Corucci , Josh C. Bongard

We study the deformation and motion of an erythrocyte in fluid flows via a lattice Boltzmann method. To this purpose, the bending rigidity and the elastic modulus of isotropic dilation are introduced and incorporated with the lattice…

Fluid Dynamics · Physics 2007-05-23 Huabing Li , Houhui Yi , Xiaowen Shan , Haiping Fang

Cell monolayers and epithelial tissues display slow dynamics during the liquid-glass transitions, a phenomenon with direct relevance to embryogenesis, tumor metastases, and wound healing. In active cells, persistent motion and cell…

Soft Condensed Matter · Physics 2024-01-25 Meng-Yuan Li , Yan-Wei Li

Recent mathematical fluid dynamics models have shed light into an outstanding problem in reproductive biology: why do spermatozoa cells show a 'preference' for swimming near to surfaces? In this paper we review quantitative approaches to…

Fluid Dynamics · Physics 2010-07-14 David J. Smith , John R. Blake

The cells and tissues that make up our body juggle contradictory mechanical demands. It is crucial for their survival to be able to withstand large mechanical loads, but it is equally crucial for them to produce forces and actively change…

Biological Physics · Physics 2019-03-22 Federica Burla , Yuval Mulla , Bart E. Vos , Anders Aufderhorst-Roberts , Gijsje H. Koenderink
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