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Coronary angiography is the "gold standard" for diagnosing coronary artery disease (CAD). At present, the methods for detecting and evaluating coronary artery stenosis cannot satisfy the clinical needs, e.g., there is no prior study of…

Image and Video Processing · Electrical Eng. & Systems 2021-12-16 Yaofang Liu , Xinyue Zhang , Wenlong Wan , Shaoyu Liu , Yingdi Liu , Hu Liu , Xueying Zeng , Qing Zhang

Coronary angiography is the gold standard imaging technique for studying and diagnosing coronary artery disease. However, the resulting 2D X-ray projections lose 3D information and exhibit visual ambiguities. In this work, we aim to…

Computer Vision and Pattern Recognition · Computer Science 2023-12-20 Yifan Wu , Rohit Jena , Mehmet Gulsun , Vivek Singh , Puneet Sharma , James C. Gee

Coronary artery stenosis is a critical health risk, and its precise identification in Coronary Angiography (CAG) can significantly aid medical practitioners in accurately evaluating the severity of a patient's condition. The complexity of…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 In Kyu Lee , Junsup Shin , Yong-Hee Lee , Jonghoe Ku , Hyun-Woo Kim

Background: Coronary Artery Disease (CAD) is one of the leading causes of death worldwide. Invasive Coronary Angiography (ICA), regarded as the gold standard for CAD diagnosis, necessitates precise vessel segmentation and stenosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Nan Mu , Ruiqi Song , Zhihui Xu , Jingfeng Jiang , Chen Zhao

In patients with coronary artery stenoses of intermediate severity, the functional significance needs to be determined. Fractional flow reserve (FFR) measurement, performed during invasive coronary angiography (ICA), is most often used in…

Computer Vision and Pattern Recognition · Computer Science 2018-08-21 Majd Zreik , Nikolas Lessmann , Robbert W. van Hamersvelt , Jelmer M. Wolterink , Michiel Voskuil , Max A. Viergever , Tim Leiner , Ivana Išgum

Accurate coronary artery segmentation from coronary computed tomography angiography is essential for quantitative coronary analysis and clinical decision support. Nevertheless, reliable segmentation remains challenging because of small…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Huan Huang , Michele Esposito , Chen Zhao

Purpose of Review Recently, machine learning has developed rapidly in the field of medicine, playing an important role in disease diagnosis. Our aim of this paper is to provide an overview of the advancements in machine learning techniques…

Medical Physics · Physics 2024-05-15 Pukar Baral , Chen Zhao , Michele Esposito , Weihua Zhou

Significant intra-observer and inter-observer variability in the interpretation of coronary angiograms are reported. This variability is in part due to the common practices that rely on performing visual inspections by specialists (e.g.,…

Quantitative Methods · Quantitative Biology 2020-02-27 Babak Ravandi , Arash Ravandi

Coronary artery disease (CAD) remains the leading cause of death globally and invasive coronary angiography (ICA) is considered the gold standard of anatomical imaging evaluation when CAD is suspected. However, risk evaluation based on ICA…

Diagnostic investigation has an important role in risk stratification and clinical decision making of patients with suspected and documented Coronary Artery Disease (CAD). However, the majority of existing tools are primarily focused on the…

Coronary Heart Disease (CHD) is a leading cause of death in the modern world. The development of modern analytical tools for diagnostics and treatment of CHD is receiving substantial attention from the scientific community. Deep…

Image and Video Processing · Electrical Eng. & Systems 2022-09-29 Maxim Popov , Temirgali Aimyshev , Eldar Ismailov , Ablay Bulegenov , Siamac Fazli

We propose a fully automated algorithm based on a deep learning framework enabling screening of a coronary computed tomography angiography (CCTA) examination for confident detection of the presence or absence of coronary artery…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Sema Candemir , Richard D. White , Mutlu Demirer , Vikash Gupta , Matthew T. Bigelow , Luciano M. Prevedello , Barbaros S. Erdal

Aortic stenosis (AS) is a degenerative valve condition that causes substantial morbidity and mortality. This condition is under-diagnosed and under-treated. In clinical practice, AS is diagnosed with expert review of transthoracic…

Image and Video Processing · Electrical Eng. & Systems 2024-04-08 Zhe Huang , Benjamin S. Wessler , Michael C. Hughes

To decrease patient waiting time for diagnosis of the Coronary Artery Disease, automatic methods are applied to identify its severity using Coronary Computed Tomography Angiography scans or extracted Multiplanar Reconstruction (MPR) images,…

Image and Video Processing · Electrical Eng. & Systems 2020-06-16 Mariia Dobko , Bohdan Petryshak , Oles Dobosevych

Cardiovascular diseases (CVDs) are the most common cause of death worldwide. Invasive x-ray coronary angiography (ICA) is one of the most important imaging modalities for the diagnosis of CVDs. ICA typically acquires only two 2D…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Yiying Wang , Abhirup Banerjee , Robin P. Choudhury , Vicente Grau

Computed Tomography Coronary Angiography (CTCA) is a non-invasive method to evaluate coronary artery anatomy and disease. CTCA is ideal for geometry reconstruction to create virtual models of coronary arteries. To our knowledge there is no…

Computer Vision and Pattern Recognition · Computer Science 2022-11-04 Ramtin Gharleghi , Dona Adikari , Katy Ellenberger , Mark Webster , Chris Ellis , Arcot Sowmya , Sze-Yuan Ooi , Susann Beier

Coronary artery disease (CAD) has posed a leading threat to the lives of cardiovascular disease patients worldwide for a long time. Therefore, automated diagnosis of CAD has indispensable significance in clinical medicine. However, the…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Xinghua Ma , Gongning Luo , Wei Wang , Kuanquan Wang

Coronary artery disease, the leading cause of cardiovascular mortality worldwide, can be assessed non-invasively by coronary computed tomography angiography (CCTA). Despite progress in automated CCTA analysis using deep learning, clinical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Jinkui Hao , Gorkem Durak , Halil Ertugrul Aktas , Ulas Bagci , Bradley D. Allen , Nilay S. Shah , Bo Zhou

Accurate segmentation of coronary arteries remains a significant challenge in clinical practice, hindering the ability to effectively diagnose and manage coronary artery disease. The lack of large, annotated datasets for model training…

Coronary angioplasty with stent implantation is the most frequently used interventional treatment for coronary artery disease. However, reocclusion within the stent, referred to as in-stent restenosis, occurs in up to 10% of lesions. It is…

Computational Engineering, Finance, and Science · Computer Science 2025-02-19 Janina C. Datz , Ivo Steinbrecher , Christoph Meier , Nora Hagmeyer , Leif-Christopher Engel , Alexander Popp , Martin R. Pfaller , Heribert Schunkert , Wolfgang A. Wall