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Despite recent advances in machine learning and explainable AI, a gap remains in personalized preventive healthcare: predictions, interventions, and recommendations should be both understandable and verifiable for all stakeholders in the…

This paper proposes a new paradigm for learning a set of independent logical rules in disjunctive normal form as an interpretable model for classification. We consider the problem of learning an interpretable decision rule set as training a…

Machine Learning · Computer Science 2021-03-15 Litao Qiao , Weijia Wang , Bill Lin

Deep learning-based AI models have been extensively applied in genomics, achieving remarkable success across diverse applications. As these models gain prominence, there exists an urgent need for interpretability methods to establish…

Genomics · Quantitative Biology 2025-05-16 Chenyu Wang , Chaoying Zuo , Zihan Su , Yuhang Xing , Lu Li , Maojun Wang , Zeyu Zhang

We propose a novel perspective to understand deep neural networks in an interpretable disentanglement form. For each semantic class, we extract a class-specific functional subnetwork from the original full model, with compressed structure…

Machine Learning · Computer Science 2019-10-08 Yulong Wang , Xiaolin Hu , Hang Su

What is it to interpret the outputs of an opaque machine learning model. One approach is to develop interpretable machine learning techniques. These techniques aim to show how machine learning models function by providing either model…

Machine Learning · Computer Science 2024-09-06 Andrew Smart , Atoosa Kasirzadeh

In recent years, work has gone into developing deep interpretable methods for image classification that clearly attributes a model's output to specific features of the data. One such of these methods is the Prototypical Part Network…

Machine Learning · Computer Science 2024-06-05 Aaron J. Li , Robin Netzorg , Zhihan Cheng , Zhuoqin Zhang , Bin Yu

Deep learning is currently playing a crucial role toward higher levels of artificial intelligence. This paradigm allows neural networks to learn complex and abstract representations, that are progressively obtained by combining simpler…

Audio and Speech Processing · Electrical Eng. & Systems 2019-08-12 Mirco Ravanelli , Yoshua Bengio

A major challenge in both neuroscience and machine learning is the development of useful tools for understanding complex information processing systems. One such tool is probes, i.e., supervised models that relate features of interest to…

Machine Learning · Computer Science 2021-04-19 Anna A. Ivanova , John Hewitt , Noga Zaslavsky

Sparse Autoencoder (SAE) has emerged as a powerful tool for mechanistic interpretability of large language models. Recent works apply SAE to protein language models (PLMs), aiming to extract and analyze biologically meaningful features from…

Quantitative Methods · Quantitative Biology 2026-01-21 Xiangyu Liu , Haodi Lei , Yi Liu , Yang Liu , Wei Hu

Deep learning methods have become very popular for the processing of natural images, and were then successfully adapted to the neuroimaging field. As these methods are non-transparent, interpretability methods are needed to validate them…

Computer Vision and Pattern Recognition · Computer Science 2022-04-15 Elina Thibeau-Sutre , Sasha Collin , Ninon Burgos , Olivier Colliot

Interpretable rationales for model predictions are crucial in practical applications. We develop neural models that possess an interpretable inference process for dependency parsing. Our models adopt instance-based inference, where…

Computation and Language · Computer Science 2021-09-29 Hiroki Ouchi , Jun Suzuki , Sosuke Kobayashi , Sho Yokoi , Tatsuki Kuribayashi , Masashi Yoshikawa , Kentaro Inui

Understanding why machine learning models behave the way they do empowers both system designers and end-users in many ways: in model selection, feature engineering, in order to trust and act upon the predictions, and in more intuitive user…

Machine Learning · Statistics 2016-06-20 Marco Tulio Ribeiro , Sameer Singh , Carlos Guestrin

Visual prompt tuning offers significant advantages for adapting pre-trained visual foundation models to specific tasks. However, current research provides limited insight into the interpretability of this approach, which is essential for…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Yubin Wang , Xinyang Jiang , De Cheng , Xiangqian Zhao , Zilong Wang , Dongsheng Li , Cairong Zhao

Deep learning models are widely used for various industrial and scientific applications. Even though these models have achieved considerable success in recent years, there exists a lack of understanding of the rationale behind decisions…

Machine Learning · Computer Science 2020-07-08 Swapnil Nitin Shah

Visual foundation models (VFMs) have become increasingly popular due to their state-of-the-art performance. However, interpretability remains crucial for critical applications. In this sense, self-explainable models (SEM) aim to provide…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Hugues Turbé , Mina Bjelogrlic , Gianmarco Mengaldo , Christian Lovis

Explaining deep learning models is of vital importance for understanding artificial intelligence systems, improving safety, and evaluating fairness. To better understand and control the CNN model, many methods for…

Machine Learning · Computer Science 2022-11-24 Zhihao Wang , Chuang Zhu

Machine Learning algorithms are increasingly being used in recent years due to their flexibility in model fitting and increased predictive performance. However, the complexity of the models makes them hard for the data analyst to interpret…

Machine Learning · Statistics 2018-06-07 Joel Vaughan , Agus Sudjianto , Erind Brahimi , Jie Chen , Vijayan N. Nair

Interpretable classification models are built with the purpose of providing a comprehensible description of the decision logic to an external oversight agent. When considered in isolation, a decision tree, a set of classification rules, or…

Machine Learning · Computer Science 2019-03-18 Riccardo Guidotti , Salvatore Ruggieri

Continual learning aims to update models under distribution shift without forgetting, yet many high-stakes deployments, such as healthcare, also require interpretability. In practice, models that adapt well (e.g., deep networks) are often…

Machine Learning · Computer Science 2026-04-21 Dongkyu Cho , Xiyue Li , Samrachana Adhikari , Rumi Chunara

Neural networks, with powerful nonlinear mapping and classification capabilities, are widely applied in mechanical fault diagnosis to ensure safety. However, being typical black-box models, their application is limited in…

Machine Learning · Computer Science 2025-02-11 Qian Chen , Xingjian Dong , Zhike Peng