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This paper investigates the numerical uncertainty of Convolutional Neural Networks (CNNs) inference for structural brain MRI analysis. It applies Random Rounding -- a stochastic arithmetic technique -- to CNN models employed in non-linear…

Image and Video Processing · Electrical Eng. & Systems 2023-08-07 Inés Gonzalez Pepe , Vinuyan Sivakolunthu , Hae Lang Park , Yohan Chatelain , Tristan Glatard

This paper introduces Quicksilver, a fast deformable image registration method. Quicksilver registration for image-pairs works by patch-wise prediction of a deformation model based directly on image appearance. A deep encoder-decoder…

Computer Vision and Pattern Recognition · Computer Science 2017-07-21 Xiao Yang , Roland Kwitt , Martin Styner , Marc Niethammer

Medical image registration is a fundamental task in medical image analysis, aiming to establish spatial correspondences between paired images. However, existing unsupervised deformable registration methods rely solely on intensity-based…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Hao Xu , Tengfei Xue , Jianan Fan , Dongnan Liu , Yuqian Chen , Fan Zhang , Carl-Fredrik Westin , Ron Kikinis , Lauren J. O'Donnell , Weidong Cai

We introduce a deep encoder-decoder architecture for image deformation prediction from multimodal images. Specifically, we design an image-patch-based deep network that jointly (i) learns an image similarity measure and (ii) the…

Computer Vision and Pattern Recognition · Computer Science 2017-04-03 Xiao Yang , Roland Kwitt , Martin Styner , Marc Niethammer

We present a method to predict image deformations based on patch-wise image appearance. Specifically, we design a patch-based deep encoder-decoder network which learns the pixel/voxel-wise mapping between image appearance and registration…

Computer Vision and Pattern Recognition · Computer Science 2016-07-11 Xiao Yang , Roland Kwitt , Marc Niethammer

In this paper, we propose a deep learning approach for image registration by predicting deformation from image appearance. Since obtaining ground-truth deformation fields for training can be challenging, we design a fully convolutional…

Computer Vision and Pattern Recognition · Computer Science 2018-02-14 Jingfan Fan , Xiaohuan Cao , Pew-Thian Yap , Dinggang Shen

The majority of deep learning (DL) based deformable image registration methods use convolutional neural networks (CNNs) to estimate displacement fields from pairs of moving and fixed images. This, however, requires the convolutional kernels…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Yihao Liu , Lianrui Zuo , Shuo Han , Yuan Xue , Jerry L. Prince , Aaron Carass

In this work we propose a deep learning network for deformable image registration (DIRNet). The DIRNet consists of a convolutional neural network (ConvNet) regressor, a spatial transformer, and a resampler. The ConvNet analyzes a pair of…

Computer Vision and Pattern Recognition · Computer Science 2017-12-08 Bob D. de Vos , Floris F. Berendsen , Max A. Viergever , Marius Staring , Ivana Išgum

Patient-specific left ventricle (LV) myocardial models have the potential to be used in a variety of clinical scenarios for improved diagnosis and treatment plans. Cine cardiac magnetic resonance (MR) imaging provides high resolution images…

Image and Video Processing · Electrical Eng. & Systems 2021-04-01 Roshan Reddy Upendra , Brian Jamison Wentz , Richard Simon , Suzanne M. Shontz , Cristian A. Linte

Deformable image registration is a critical technology in medical image analysis, with broad applications in clinical practice such as disease diagnosis, multi-modal fusion, and surgical navigation. Traditional methods often rely on…

Image and Video Processing · Electrical Eng. & Systems 2026-03-04 Zhengyong Huang , Xingwen Sun , Xuting Chang , Ning Jiang , Yao Wang , Jianfei Sun , Hongbin Han , Yao Sui

Medical image registration drives quantitative analysis across organs, modalities, and patient populations. Recent deep learning methods often combine low-level "trend-driven" computational blocks from computer vision, such as large-kernel…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Bailiang Jian , Jiazhen Pan , Rohit Jena , Morteza Ghahremani , Hongwei Bran Li , Daniel Rueckert , Christian Wachinger , Benedikt Wiestler

This paper proposes a new framework and algorithms to address the problem of diffeomorphic registration on a general class of geometric objects that can be described as discrete distributions of local direction vectors. It builds on both…

Optimization and Control · Mathematics 2018-02-15 Hsi-Wei Hsieh , Nicolas Charon

To accurately analyze changes of anatomical structures in longitudinal imaging studies, consistent segmentation across multiple time-points is required. Existing solutions often involve independent registration and segmentation components.…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Bo Li , Wiro Niessen , Stefan Klein , Marius de Groot , Arfan Ikram , Meike Vernooij , Esther Bron

Melanoma brain metastases (MBM) are common and spatially heterogeneous lesions, complicating cohort-level analyses due to anatomical variability and differing MRI protocols. We propose a fully differentiable, deep-learning-based deformable…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Nanna E. Wielenberg , Ilinca Popp , Oliver Blanck , Lucas Zander , Jan C. Peeken , Stephanie E. Combs , Anca-Ligia Grosu , Dimos Baltas , Tobias Fechter

Deformable medical image registration is a crucial aspect of medical image analysis. In recent years, researchers have begun leveraging auxiliary tasks (such as supervised segmentation) to provide anatomical structure information for the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Hongchao Zhou , Shunbo Hu

Image registration has traditionally been done using two distinct approaches: learning based methods, relying on robust deep neural networks, and optimization-based methods, applying complex mathematical transformations to warp images…

Computer Vision and Pattern Recognition · Computer Science 2024-01-22 Gabriel De Araujo , Shanlin Sun , Xiaohui Xie

The CLARITY method renders brains optically transparent to enable high-resolution imaging in the structurally intact brain. Anatomically annotating CLARITY brains is necessary for discovering which regions contain signals of interest.…

Quantitative Methods · Quantitative Biology 2016-05-09 Kwame S. Kutten , Joshua T. Vogelstein , Nicolas Charon , Li Ye , Karl Deisseroth , Michael I. Miller

Image registration has been widely studied over the past several decades, with numerous applications in science, engineering and medicine. Most of the conventional mathematical models for large deformation image registration rely on…

Computer Vision and Pattern Recognition · Computer Science 2022-06-30 Ho Law , Gary P. T. Choi , Ka Chun Lam , Lok Ming Lui

Cardiovascular magnetic resonance (CMR) is the gold standard for assessing cardiac function, but individual cardiac cycles complicate automatic temporal comparison or sub-phase analysis. Accurate cardiac keyframe detection can eliminate…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Sven Koehler , Sarah Kaye Mueller , Jonathan Kiekenap , Gerald Greil , Tarique Hussain , Samir Sarikouch , Florian André , Norbert Frey , Sandy Engelhardt

Objectives: Computerized phantoms play an essential role in various applications of medical imaging research. Although the existing computerized phantoms can model anatomical variations through organ and phantom scaling, this does not…

Image and Video Processing · Electrical Eng. & Systems 2021-04-20 Junyu Chen , Ye Li , Yong Du , Eric C. Frey
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