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The establishment of image correspondence through robust image registration is critical to many clinical tasks such as image fusion, organ atlas creation, and tumor growth monitoring, and is a very challenging problem. Since the beginning…

Quantitative Methods · Quantitative Biology 2020-01-22 Grant Haskins , Uwe Kruger , Pingkun Yan

Deformable image registration is a crucial step in medical image analysis for finding a non-linear spatial transformation between a pair of fixed and moving images. Deep registration methods based on Convolutional Neural Networks (CNNs)…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Mingyuan Meng , Lei Bi , Dagan Feng , Jinman Kim

Deformable image registration poses a challenging problem where, unlike most deep learning tasks, a complex relationship between multiple coordinate systems has to be considered. Although data-driven methods have shown promising…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Vasiliki Sideri-Lampretsa , Nil Stolt-Ansó , Huaqi Qiu , Julian McGinnis , Wenke Karbole , Martin Menten , Daniel Rueckert

Deep learning has emerged as a strong alternative for classical iterative methods for deformable medical image registration, where the goal is to find a mapping between the coordinate systems of two images. Popular classical image…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Joel Honkamaa , Pekka Marttinen

Image registration is used in many medical image analysis applications, such as tracking the motion of tissue in cardiac images, where cardiac kinematics can be an indicator of tissue health. Registration is a challenging problem for deep…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Benjamin Graham

Deformable image registration (DIR), aiming to find spatial correspondence between images, is one of the most critical problems in the domain of medical image analysis. In this paper, we present a novel, generic, and accurate diffeomorphic…

Computer Vision and Pattern Recognition · Computer Science 2023-02-08 Yifan Wu , Tom Z. Jiahao , Jiancong Wang , Paul A. Yushkevich , M. Ani Hsieh , James C. Gee

Medical image registration is a fundamental task in medical image analysis, aiming to establish spatial correspondences between paired images. However, existing unsupervised deformable registration methods rely solely on intensity-based…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Hao Xu , Tengfei Xue , Jianan Fan , Dongnan Liu , Yuqian Chen , Fan Zhang , Carl-Fredrik Westin , Ron Kikinis , Lauren J. O'Donnell , Weidong Cai

Image registration is a fundamental requirement for medical image analysis. Deep registration methods based on deep learning have been widely recognized for their capabilities to perform fast end-to-end registration. Many deep registration…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Mingyuan Meng , Lei Bi , Michael Fulham , Dagan Feng , Jinman Kim

Recently, deep-learning-based approaches have been widely studied for deformable image registration task. However, most efforts directly map the composite image representation to spatial transformation through the convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Jiashun Chen , Donghuan Lu , Yu Zhang , Dong Wei , Munan Ning , Xinyu Shi , Zhe Xu , Yefeng Zheng

Spatial transformer networks (STNs) were designed to enable convolutional neural networks (CNNs) to learn invariance to image transformations. STNs were originally proposed to transform CNN feature maps as well as input images. This enables…

Computer Vision and Pattern Recognition · Computer Science 2024-09-19 Lukas Finnveden , Ylva Jansson , Tony Lindeberg

Deformable medical image registration plays an important role in clinical diagnosis and treatment. Recently, the deep learning (DL) based image registration methods have been widely investigated and showed excellent performance in…

Image and Video Processing · Electrical Eng. & Systems 2022-10-18 Yibo Wang , Wen Qian , Xuming Zhang

Registration of images with pathologies is challenging due to tissue appearance changes and missing correspondences caused by the pathologies. Moreover, mass effects as observed for brain tumors may displace tissue, creating larger…

Image and Video Processing · Electrical Eng. & Systems 2020-08-19 Xu Han , Zhengyang Shen , Zhenlin Xu , Spyridon Bakas , Hamed Akbari , Michel Bilello , Christos Davatzikos , Marc Niethammer

Spatial transformer networks (STNs) were designed to enable CNNs to learn invariance to image transformations. STNs were originally proposed to transform CNN feature maps as well as input images. This enables the use of more complex…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Lukas Finnveden , Ylva Jansson , Tony Lindeberg

Deformable image registration aims to find a dense non-linear spatial correspondence between a pair of images, which is a crucial step for many medical tasks such as tumor growth monitoring and population analysis. Recently, Deep Neural…

Image and Video Processing · Electrical Eng. & Systems 2025-01-09 Mingyuan Meng , Michael Fulham , Dagan Feng , Lei Bi , Jinman Kim

Deep learning (DL) image registration methods amortize the costly pair-wise iterative optimization by training deep neural networks to predict the optimal transformation in one fast forward-pass. In this work, we bridge the gap between…

Image and Video Processing · Electrical Eng. & Systems 2022-09-13 Huaqi Qiu , Kerstin Hammernik , Chen Qin , Chen Chen , Daniel Rueckert

Deformable image registration is fundamental to longitudinal and population analysis. Geometric alignment of the infant brain MR images is challenging, owing to rapid changes in image appearance in association with brain development. In…

Computer Vision and Pattern Recognition · Computer Science 2020-07-07 Dongming Wei , Sahar Ahmad , Yunzhi Huang , Lei Ma , Zhengwang Wu , Gang Li , Li Wang , Qian Wang , Pew-Thian Yap , Dinggang Shen

Transformers have been recently adapted for large scale image classification, achieving high scores shaking up the long supremacy of convolutional neural networks. However the optimization of image transformers has been little studied so…

Computer Vision and Pattern Recognition · Computer Science 2021-04-08 Hugo Touvron , Matthieu Cord , Alexandre Sablayrolles , Gabriel Synnaeve , Hervé Jégou

Rigid registration aims to determine the translations and rotations necessary to align features in a pair of images. While recent machine learning methods have become state-of-the-art for linear and deformable registration across subjects,…

Image and Video Processing · Electrical Eng. & Systems 2025-12-08 Jingru Fu , Adrian V. Dalca , Bruce Fischl , Rodrigo Moreno , Malte Hoffmann

Spatial Transformer Networks (STNs) estimate image transformations that can improve downstream tasks by `zooming in' on relevant regions in an image. However, STNs are hard to train and sensitive to mis-predictions of transformations. To…

Machine Learning · Computer Science 2022-06-16 Pola Schwöbel , Frederik Warburg , Martin Jørgensen , Kristoffer H. Madsen , Søren Hauberg

Conventional deformable registration methods aim at solving an optimization model carefully designed on image pairs and their computational costs are exceptionally high. In contrast, recent deep learning based approaches can provide fast…

Computer Vision and Pattern Recognition · Computer Science 2021-10-01 Risheng Liu , Zi Li , Xin Fan , Chenying Zhao , Hao Huang , Zhongxuan Luo