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Related papers: Learning Multimorbidity Patterns from Electronic H…

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Chronic diseases frequently co-occur in patterns that are unlikely to arise by chance, a phenomenon known as multimorbidity. This growing challenge for patients and healthcare systems is amplified by demographic aging and the rising burden…

Physics and Society · Physics 2025-10-14 Johanna Einsiedler , Katharina Ledebur , Peter Klimek , Laust Hvas Mortensen

Non-negative matrix factorization (NMF) is a prob- lem with many applications, ranging from facial recognition to document clustering. However, due to the variety of algorithms that solve NMF, the randomness involved in these algorithms,…

Numerical Analysis · Mathematics 2018-12-17 Connor Sell , Jeremy Kepner

Health conditions among patients in intensive care units (ICUs) are monitored via electronic health records (EHRs), composed of numerical time series and lengthy clinical note sequences, both taken at irregular time intervals. Dealing with…

Machine Learning · Computer Science 2023-06-07 Xinlu Zhang , Shiyang Li , Zhiyu Chen , Xifeng Yan , Linda Petzold

The increase in availability of longitudinal electronic health record (EHR) data is leading to improved understanding of diseases and discovery of novel phenotypes. The majority of clustering algorithms focus only on patient trajectories,…

Machine Learning · Computer Science 2021-11-12 Oliver Carr , Avelino Javer , Patrick Rockenschaub , Owen Parsons , Robert Dürichen

In electronic health records (EHRs), clustering patients and distinguishing disease subtypes are key tasks to elucidate pathophysiology and aid clinical decision-making. However, clustering in healthcare informatics is still based on…

Machine Learning · Computer Science 2026-04-09 Manar D. Samad , Yina Hou , Shrabani Ghosh

Nonnegative Matrix Factorization (NMF) is a widely used technique for data representation. Inspired by the expressive power of deep learning, several NMF variants equipped with deep architectures have been proposed. However, these methods…

Machine Learning · Computer Science 2017-11-21 Yuning Qiu , Guoxu Zhou , Kan Xie

The availability of large and deep electronic healthcare records (EHR) datasets has the potential to enable a better understanding of real-world patient journeys, and to identify novel subgroups of patients. ML-based aggregation of EHR data…

Machine Learning · Computer Science 2022-08-03 Owen Parsons , Nathan E Barlow , Janie Baxter , Karen Paraschin , Andrea Derix , Peter Hein , Robert Dürichen

Objectives: The fee-for-service approach to healthcare leads to the management of a patient's conditions in an independent manner, inducing various negative consequences. It is recognized that a bundled care approach to healthcare-one that…

Computers and Society · Computer Science 2017-06-05 You Chen , Abel N. Kho , David Liebovitz , Catherine Ivory , Sarah Osmundson , Jiang Bian , Bradley A. Malin

The integration of diverse clinical modalities such as medical imaging and the tabular data extracted from patients' Electronic Health Records (EHRs) is a crucial aspect of modern healthcare. Integrative analysis of multiple sources can…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Daniel Duenias , Brennan Nichyporuk , Tal Arbel , Tammy Riklin Raviv

Initial hours of hospital admission impact clinical trajectory, but early clinical decisions often suffer due to data paucity. With clustering analysis for vital signs within six hours of admission, patient phenotypes with distinct…

Cancer, with its inherent heterogeneity, is commonly categorized into distinct subtypes based on unique traits, cellular origins, and molecular markers specific to each type. However, current studies primarily rely on complete multi-omics…

Machine Learning · Computer Science 2024-11-26 Yingxuan Ren , Fengtao Ren , Bo Yang

Integrating multimodal Electronic Health Records (EHR) data, such as numerical time series and free-text clinical reports, has great potential in predicting clinical outcomes. However, prior work has primarily focused on capturing temporal…

Machine Learning · Computer Science 2025-11-10 Fuying Wang , Feng Wu , Yihan Tang , Lequan Yu

Multimorbidity research in mental health services requires data from physical health conditions which is traditionally limited in mental health care electronic health records. In this study, we aimed to extract data from physical health…

Clustering on the data with multiple aspects, such as multi-view or multi-type relational data, has become popular in recent years due to their wide applicability. The approach using manifold learning with the Non-negative Matrix…

Machine Learning · Computer Science 2020-09-08 Khanh Luong , Richi Nayak

In this work, we apply topic modeling using Non-Negative Matrix Factorization (NMF) on the COVID-19 Open Research Dataset (CORD-19) to uncover the underlying thematic structure and its evolution within the extensive body of COVID-19…

Computation and Language · Computer Science 2025-03-25 Divya Patel , Vansh Parikh , Om Patel , Agam Shah , Bhaskar Chaudhury

Electronic medical records (EMRs) supports the development of machine learning algorithms for predicting disease incidence, patient response to treatment, and other healthcare events. But insofar most algorithms have been centralized,…

Machine Learning · Computer Science 2019-03-25 Li Huang , Dianbo Liu

Electronic health records (EHRs) are designed to synthesize diverse data types, including unstructured clinical notes, structured lab tests, and time-series visit data. Physicians draw on these multimodal and temporal sources of EHR data to…

Background: Electronic Health Records (EHRs) contain rich information of patients' health history, which usually include both structured and unstructured data. There have been many studies focusing on distilling valuable information from…

Machine Learning · Computer Science 2021-11-10 Ziyi Liu , Jiaqi Zhang , Yongshuai Hou , Xinran Zhang , Ge Li , Yang Xiang

Due to the wider availability of modern electronic health records, patient care data is often being stored in the form of time-series. Clustering such time-series data is crucial for patient phenotyping, anticipating patients' prognoses by…

Medical Physics · Physics 2020-06-17 Changhee Lee , Mihaela van der Schaar

Electronic phenotyping is the task of ascertaining whether an individual has a medical condition of interest by analyzing their medical record and is foundational in clinical informatics. Increasingly, electronic phenotyping is performed…

Machine Learning · Statistics 2019-01-08 Daisy Yi Ding , Chloé Simpson , Stephen Pfohl , Dave C. Kale , Kenneth Jung , Nigam H. Shah