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Background: Clinical trials are designed to prove the efficacy of an intervention by means of model-based approaches involving parametric hypothesis testing. Issues arise when no effect is observed in the study population. Indeed, an effect…

Simultaneous recordings from multiple neural units allow us to investigate the activity of very large neural ensembles. To understand how large ensembles of neurons process sensory information, it is necessary to develop suitable…

Neurons and Cognition · Quantitative Biology 2013-05-30 Fernando Montani , Elena Phoka , Mariela Portesi , Simon R. Schultz

In this work, we present a transformer-based framework for predicting future pedestrian states based on clustered historical trajectory data. In previous studies, researchers propose enhancing pedestrian trajectory predictions by using…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Kleio Fragkedaki , Frank J. Jiang , Karl H. Johansson , Jonas Mårtensson

Matrices are two-dimensional data structures allowing one to conceptually organize information. For example, adjacency matrices are useful to store the links of a network; correlation matrices are simple ways to arrange gene co-expression…

Disordered Systems and Neural Networks · Physics 2022-09-29 Flaviano Morone

In this paper we present a method for the unsupervised clustering of high-dimensional binary data, with a special focus on electronic healthcare records. We present a robust and efficient heuristic to face this problem using tensor…

Machine Learning · Statistics 2017-08-31 Matteo Ruffini , Ricard Gavaldà , Esther Limón

Data clustering is an approach to seek for structure in sets of complex data, i.e., sets of "objects". The main objective is to identify groups of objects which are similar to each other, e.g., for classification. Here, an introduction to…

Data Analysis, Statistics and Probability · Physics 2016-02-17 Alexander K. Hartmann

In data containing heterogeneous subpopulations, classification performance benefits from incorporating the knowledge of cluster structure in the classifier. Previous methods for such combined clustering and classification either 1) are…

Machine Learning · Computer Science 2023-01-04 Shivin Srivastava , Siddharth Bhatia , Lingxiao Huang , Lim Jun Heng , Kenji Kawaguchi , Vaibhav Rajan

This paper introduces a new unsupervised method for the clustering of physiological data into health states based on their similarity. We propose an iterative hierarchical clustering approach that combines health states according to a…

Signal Processing · Electrical Eng. & Systems 2018-03-28 Fabian Schrumpf , Gerold Bausch , Matthias Sturm , Mirco Fuchs

In cluster analysis, a common first step is to scale the data aiming to better partition them into clusters. Even though many different techniques have throughout many years been introduced to this end, it is probably fair to say that the…

Machine Learning · Computer Science 2023-05-30 Eduardo J. Aguilar , Valmir C. Barbosa

In today's world, healthcare is the most important factor affecting human life. Due to heavy work load it is not possible for personal healthcare. The proposed system acts as a preventive measure for determining whether a person is fit or…

The process of manually searching for relevant instances in, and extracting information from, clinical databases underpin a multitude of clinical tasks. Such tasks include disease diagnosis, clinical trial recruitment, and continuing…

Signal Processing · Electrical Eng. & Systems 2021-10-05 Dani Kiyasseh , Tingting Zhu , David A. Clifton

Disease mapping is the field of spatial epidemiology interested in estimating the spatial pattern in disease risk across $n$ areal units. One aim is to identify units exhibiting elevated disease risks, so that public health interventions…

Applications · Statistics 2013-11-05 Craig Anderson , Duncan Lee , Nema Dean

We consider the problem of model-based clustering in the presence of many correlated, mixed continuous and discrete variables, some of which may have missing values. Discrete variables are treated with a latent continuous variable approach…

Multilevel models (mixed-effect models or hierarchical linear models) are now a standard approach to analysing clustered and longitudinal data in the social, behavioural and medical sciences. This review article focuses on multilevel linear…

Methodology · Statistics 2019-07-16 George Leckie

A common challenge in data analysis is uncovering relationships between predictors and responses in problems involving large numbers of both. When the number of predictors and responses is limited, visual approaches are particularly…

Computation · Statistics 2026-05-29 Gabriel McCoy , German Valencia , Ursula Laa

Cluster analysis aims at separating patients into phenotypically heterogenous groups and defining therapeutically homogeneous patient subclasses. It is an important approach in data-driven disease classification and subtyping. Acute…

Quantitative Methods · Quantitative Biology 2019-03-28 Eryu Xia , Xin Du , Jing Mei , Wen Sun , Suijun Tong , Zhiqing Kang , Jian Sheng , Jian Li , Changsheng Ma , Jianzeng Dong , Shaochun Li

Healthcare datasets often contain groups of highly correlated features, such as features from the same biological system. When feature selection is applied to these datasets to identify the most important features, the biases inherent in…

Machine Learning · Computer Science 2022-07-07 Annette Spooner , Gelareh Mohammadi , Perminder S. Sachdev , Henry Brodaty , Arcot Sowmya

The largest collection of medical evidence in the world is PubMed. However, the significant barrier in accessing and extracting information is information organization. A factor that contributes towards this barrier is managing medical…

Information Retrieval · Computer Science 2018-09-07 Michael Segundo Ortiz , Sam Bubnovich , Mengqian Wang , Kazuhiro Seki Ph. D. , Javed Mostafa Ph. D

Clustering is widely used in unsupervised learning to find homogeneous groups of observations within a dataset. However, clustering mixed-type data remains a challenge, as few existing approaches are suited for this task. This study…

Machine Learning · Statistics 2025-11-26 Badih Ghattas , Alvaro Sanchez San-Benito

Exploring tabular datasets to understand how different feature pairs partition data into meaningful cohorts is crucial in domains such as biomarker discovery, yet comparing clusters across multiple feature pair projections is challenging.…

Human-Computer Interaction · Computer Science 2026-01-21 Lukas Schilcher , Peter Waldert , Benedikt Kantz , Tobias Schreck