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Coarse-graining has become an area of tremendous importance within many different research fields. For molecular simulation, coarse-graining bears the promise of finding simplified models such that long-time simulations of large-scale…

Chemical Physics · Physics 2019-09-04 Feliks Nüske , Lorenzo Boninsegna , Cecilia Clementi

The Asakura-Oosawa model for colloid-polymer mixtures is studied by Monte Carlo simulations at densities inside the two-phase coexistence region of fluid and solid. Choosing a geometry where the system is confined between two flat walls,…

Soft Condensed Matter · Physics 2015-06-04 Debabrata Deb , Alexander Winkler , Peter Virnau , Kurt Binder

We implemented a coarse-graining procedure to construct mesoscopic models of complex molecules. The final aim is to obtain better results on properties depending on slow modes of the molecules. Therefore the number of particles considered…

Soft Condensed Matter · Physics 2009-10-31 Hendrik Meyer , Oliver Biermann , Roland Faller , Dirk Reith , Florian Mueller-Plathe

We propose a novel and systematic method for coarse-graining oscillator networks described by phase equations. Our coarse-graining method enables us to obtain the closed coarse-grained equations for a few effective eigenmodes, which is…

Adaptation and Self-Organizing Systems · Physics 2013-11-06 Yuki Izumida , Hiroshi Kori

A coarse-graining strategy, previously developed for polymer solutions, is extended here to mixtures of linear polymers and hard-sphere colloids. In this approach groups of monomers are mapped onto a single pseudoatom (a blob) and the…

Soft Condensed Matter · Physics 2015-01-07 Giuseppe D'Adamo , Andrea Pelissetto , Carlo Pierleoni

We study the structure of colloidal fluids with reference to colloid-polymer mixtures. We compare the one component description of the Asakura-Oosawa (AO) idealisation of colloid-polymer mixtures with the full two-component model. We also…

Soft Condensed Matter · Physics 2015-01-20 Jade Taffs , Alex Malins , Stephen R. Williams , C. Patrick Royall

We present a multilevel Monte Carlo simulation method for analysing multi-scale physical systems via a hierarchy of coarse-grained representations, to obtain numerically-exact results, at the most detailed level. We apply the method to a…

Statistical Mechanics · Physics 2022-10-04 Paul B. Rohrbach , Hideki Kobayashi , Robert Scheichl , Nigel B. Wilding , Robert L. Jack

Due to the wide range of timescales that are present in macromolecular systems, hierarchical multiscale strategies are necessary for their computational study. Coarse-graining (CG) allows to establish a link between different system…

We develop a systematic coarse-graining procedure which establishes the connection between models of mixtures of immiscible fluids at different length and time scales. We start from the Cahn-Hilliard model of spinodal decomposition in a…

Statistical Mechanics · Physics 2015-05-14 Asja Jelic , Patrick Ilg , Hans Christian Öttinger

The Single Chain Mean Field theory is used to simulate the equilibrium structure of phospholipid membranes at the molecular level. Three levels of coarse-graining of DMPC phospholipid surfactants are present: the detailed 44-beads double…

Soft Condensed Matter · Physics 2010-09-29 Sergey Pogodin , Vladimir A. Baulin

We study the Asakura-Oosawa model in the "protein limit", where the penetrable sphere radius $R_{AO}$ is much greater than the hard sphere radius $R_c$. The phase behaviour and structure calculated with a full many-body treatment show…

Condensed Matter · Physics 2009-11-10 A. Moncho-Jorda , A. A. Louis , P. G. Bolhuis , R. Roth

Monte Carlo simulations at constant pressure are performed to study coexistence and interfacial properties of the liquid-solid transition in hard spheres and in colloid-polymer mixtures. The latter system is described as a one-component…

Soft Condensed Matter · Physics 2015-05-18 T. Zykova-Timan , J. Horbach , K. Binder

Atomistic or ab-initio molecular dynamics simulations are widely used to predict thermodynamics and kinetics and relate them to molecular structure. A common approach to go beyond the time- and length-scales accessible with such…

The influence of confinement, due to flat parallel structureless walls, on phase separation in colloid-polymer mixtures, is investigated by means of grand-canonical Monte Carlo simulations. Ultra-thin films, with thicknesses between…

Soft Condensed Matter · Physics 2009-11-11 Richard L. C. Vink , Andres De Virgiliis , Juergen Horbach , Kurt Binder

We present a novel thermodynamically guided, low-noise, time-scale bridging, and pertinently efficient strategy for the dynamic simulation of microscopic models for complex fluids. The systematic coarse-graining method is exemplified for…

Soft Condensed Matter · Physics 2010-11-12 Patrick Ilg , Hans Christian Öttinger , Martin Kröger

We present a new computational framework combining coarse-graining techniques with bootstrap methods to study quantum many-body systems. The method efficiently computes rigorous upper and lower bounds on both zero- and finite-temperature…

High Energy Physics - Theory · Physics 2025-11-25 Minjae Cho , Colin Oscar Nancarrow , Petar Tadić , Yuan Xin , Zechuan Zheng

Certain sequences of peptoid polymers (synthetic analogs of peptides) assemble into bilayer nanosheets via a nonequilibrium assembly pathway of adsorption, compression, and collapse at an air-water interface. As with other large-scale…

Biological Physics · Physics 2014-10-01 Thomas K. Haxton , Ranjan V. Mannige , Ronald N. Zuckermann , Stephen Whitelam

We present a promising coarse-graining strategy for linking micro- and mesoscales of soft matter systems. The approach is based on effective pairwise interaction potentials obtained from detailed atomistic molecular dynamics (MD)…

Soft Condensed Matter · Physics 2007-05-23 A. P. Lyubartsev , M. Karttunen , I. Vattulainen , A. Laaksonen

We use a two-level simulation method to analyse the critical point associated with demixing of binary hard sphere mixtures. The method exploits an accurate coarse-grained model with two-body and three-body effective interactions. Using this…

Statistical Mechanics · Physics 2021-10-13 Hideki Kobayashi , Paul B. Rohrbach , Robert Scheichl , Nigel B. Wilding , Robert L. Jack

We present a Monte Carlo method to simulate asymmetric binary mixtures in the grand canonical ensemble. The method is used to study the colloid-polymer model of Asakura and Oosawa. We determine the phase diagram of the fluid-fluid unmixing…

Soft Condensed Matter · Physics 2007-05-23 R. L. C. Vink , J. Horbach