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Trabecular bone is a lightweight, compliant material organized as a web of struts and rods (trabeculae) that erode with age and the onset of bone diseases like osteoporosis, leading to increased fracture risk. The traditional diagnostic…

Medical Physics · Physics 2019-06-26 Avik Mondal , Chantal Nguyen , Xiao Ma , Ahmed E. Elbanna , Jean M. Carlson

Nowadays, additive manufacturing processes greatly simplify the production of openwork workpiece providing new opportunities for workpieces design. Based on Nature knowledge, a new bio-inspired workpiece structural optimization approach is…

Medical Physics · Physics 2018-10-29 Clement Audibert , Julien Chaves-Jacob , Jean-Marc Linares , Quentin-Alexis Lopez

Materials with network-like microstructure, including polymers, are the backbone for many natural and human-made materials such as gels, biological tissues, metamaterials, and rubbers. Fracture processes in these networked materials are…

Soft Condensed Matter · Physics 2020-01-29 Ahmed Ghareeb , Ahmed Elbanna

The structural analysis of shape boundaries leads to the characterization of objects as well as to the understanding of shape properties. The literature on graphs and networks have contributed to the structural characterization of shapes…

Computer Vision and Pattern Recognition · Computer Science 2017-11-15 Gisele H. B. Miranda , Jeaneth Machicao , Odemir M. Bruno

The fracture resistance of structures is optimised using the level-set method. Fracture resistance is assumed to be related to the elastic energy released by a crack propagating in a normal direction from parts of the boundary which are in…

Materials Science · Physics 2007-05-23 V. J. Challis , A. P. Roberts , A. H. Wilkins

Natural hard composites like human bone possess a combination of strength and toughness that exceeds that of their constituents and of many engineered composites. This augmentation is attributed to their complex hierarchical structure,…

We propose a mapping from fracture systems consisting of intersecting fracture sheets in three dimensions to an abstract network consisting of nodes and links. This makes it possible to analyze fracture systems with the methods developed…

Data Analysis, Statistics and Probability · Physics 2013-11-05 Christian André Andresen , Alex Hansen , Romain Le Goc , Philippe Davy , Sigmund Mongstad Hope

Porous structures such as trabecular bone are widely seen in nature. These structures exhibit superior mechanical properties whilst being lightweight. In this paper, we present a method to generate bone-like porous structures as lightweight…

Graphics · Computer Science 2018-05-01 Jun Wu , Niels Aage , Ruediger Westermann , Ole Sigmund

Bone adaptation models are often solved in the forward direction, meaning that the response of bone to a given set of loads is determined by running a bone tissue adaptation model. The model is generally solved using a numerical technique…

Tissues and Organs · Quantitative Biology 2012-01-31 Amir A. Zadpoor , Gianni Campoli , Harrie Weinans

This article describes the application of recently introduced complex networks concepts and methods to the characterization and analysis of cortical bone structure. Three-dimensional reconstructions of the system of channels underlying bone…

Tissues and Organs · Quantitative Biology 2007-05-23 Luciano da Fontoura Costa , Matheus Palhares Viana , Marcelo Emilio Beletti

Inference of the network structure (e.g., routing topology) and dynamics (e.g., link performance) is an essential component in many network design and management tasks. In this paper we propose a new, general framework for analyzing and…

Networking and Internet Architecture · Computer Science 2019-11-13 Jian Ni , Sekhar Tatikonda

A preliminary iterative 3D meso-scale structural model of the femur was developed, in which bar and shell elements were used to represent trabecular and cortical bone respectively. The cross-sectional areas of the bar elements and the…

Medical Physics · Physics 2012-03-01 Andrew T. M. Phillips

Recent genomic and bioinformatic advances have motivated the development of numerous random network models purporting to describe graphs of biological, technological, and sociological origin. The success of a model has been evaluated by how…

Molecular Networks · Quantitative Biology 2007-05-23 Manuel Middendorf , Etay Ziv , Carter Adams , Jen Hom , Robin Koytcheff , Chaya Levovitz , Gregory Woods , Linda Chen , Chris Wiggins

Inspired by studies on the airports' network and the physical Internet, we propose a general model of weighted networks via an optimization principle. The topology of the optimal network turns out to be a spanning tree that minimizes a…

Physics and Society · Physics 2009-11-11 Marc Barthelemy , Alessandro Flammini

Networked structure emerged from a wide range of fields such as biological systems, World Wide Web and technological infrastructure. A deeply insight into the topological complexity of these networks has been gained. Some works start to pay…

Physics and Society · Physics 2012-02-03 Jiang Xiongfei

Networked structures arise in a wide array of different contexts such as technological and transportation infrastructures, social phenomena, and biological systems. These highly interconnected systems have recently been the focus of a great…

Statistical Mechanics · Physics 2009-11-10 Alain Barrat , Marc Barthelemy , Romualdo Pastor-Satorras , Alessandro Vespignani

We introduce a continuous modeling approach which combines elastic responds of the trabecular bone structure, the concentration of signaling molecules within the bone and a mechanism how this concentration at the bone surface is used for…

Tissues and Organs · Quantitative Biology 2017-11-21 S. Aland , F. Stenger , R. Müller , M. Kampschulte , A. C. Langheinrich , T. El Khassawna , C. Heiß , A. Dreutsch , A. Voigt

We propose a new method for quantitative characterization of spatial network-like patterns with loops, such as surface fracture patterns, leaf vein networks and patterns of urban streets. Such patterns are not well characterized by purely…

Pattern Formation and Solitons · Physics 2015-05-20 Andrea Perna , Pascale Kuntz , Stéphane Douady

The organization in brain networks shows highly modular features with weak inter-modular interaction. The topology of the networks involves emergence of modules and sub-modules at different levels of constitution governed by fractal laws.…

Neurons and Cognition · Quantitative Biology 2015-09-22 Soibam Shyamchand Singh , Khundrakpam Budhachandra Singh , Romana Ishrat , B. Indrajit Sharma , R. K. Brojen Singh

Bone adapts in response to its mechanical environment. This evolution of bone density is one of the most important mechanisms for developing fracture resistance. A finite element framework for simulating bone adaptation, commonly called…

Computational Engineering, Finance, and Science · Computer Science 2020-01-06 Karol Lewandowski , Łukasz Kaczmarczyk , Ignatios Athanasiadis , John F. Marshall , Chris J. Pearce
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