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Thanks to novel, powerful brain activity recording techniques, we can create data-driven models from thousands of recording channels and large portions of the cortex, which can improve our understanding of brain-states neuromodulation and…

Fifty years ago, John von Neumann compared the architecture of the brain with that of computers that he invented and which is still in use today. In those days, the organisation of computers was based on concepts of brain organisation.…

Neurons and Cognition · Quantitative Biology 2008-02-28 Marcus Kaiser

We advocate here the use of computational logic for systems biology, as a \emph{unified and safe} framework well suited for both modeling the dynamic behaviour of biological systems, expressing properties of them, and verifying these…

Quantitative Methods · Quantitative Biology 2020-10-07 Elisabetta de Maria , Joelle Despeyroux , Amy Felty , Pietro Liò , Carlos Olarte , Abdorrahim Bahrami

Cognitive control is a suite of processes that helps individuals pursue goals despite resistance or uncertainty about what to do. Although cognitive control has been extensively studied as a dynamic feedback loop of perception, valuation,…

The past few years have witnessed an increased interest in learning Hamiltonian dynamics in deep learning frameworks. As an inductive bias based on physical laws, Hamiltonian dynamics endow neural networks with accurate long-term…

Machine Learning · Computer Science 2022-03-02 Zhijie Chen , Mingquan Feng , Junchi Yan , Hongyuan Zha

Low-dimensional yet rich dynamics often emerge in the brain. Examples include oscillations and chaotic dynamics during sleep, epilepsy, and voluntary movement. However, a general mechanism for the emergence of low dimensional dynamics…

Neurons and Cognition · Quantitative Biology 2018-08-29 Wilten Nicola , Peter Hellyer , Sue Ann Campbell , Claudia Clopath

Neuroscience research is undergoing a minor revolution. Recent advances in machine learning and artificial intelligence (AI) research have opened up new ways of thinking about neural computation. Many researchers are excited by the…

Neurons and Cognition · Quantitative Biology 2020-04-20 Andrew Saxe , Stephanie Nelli , Christopher Summerfield

Tremendous neuroscientific progress has recently been made by mapping brain connectivity, complementing extensive knowledge of task-evoked brain activation patterns. However, despite evidence that they are related, these connectivity and…

Neurons and Cognition · Quantitative Biology 2024-02-06 Michael W. Cole

Deciphering the underpinnings of the dynamical processes leading to information transmission, processing, and storing in the brain is a crucial challenge in neuroscience. An inspiring but speculative theoretical idea is that such dynamics…

Statistical Mechanics · Physics 2023-07-21 Guillermo B. Morales , Serena Di Santo , Miguel A. Muñoz

A central challenge in the computational modeling of neural dynamics is the trade-off between accuracy and simplicity. At the level of individual neurons, nonlinear dynamics are both experimentally established and essential for neuronal…

The history of computer science and brain sciences are intertwined. In his unfinished manuscript "The Computer and the Brain," von Neumann debates whether or not the brain can be thought of as a computing machine and identifies some of the…

Computers and Society · Computer Science 2020-04-28 Polina Golland , Jack Gallant , Greg Hager , Hanspeter Pfister , Christos Papadimitriou , Stefan Schaal , Joshua T. Vogelstein

'If I cannot build it, I do not understand it.' So said Nobel laureate Richard Feynman, and by his metric, we understand a bit about physics, less about chemistry, and almost nothing about biology. When we fully understand a phenomenon, we…

Neurons and Cognition · Quantitative Biology 2017-04-13 Richard Granger

In this short essay, we discuss some basic features of cognitive activity at several different space-time scales: from neural networks in the brain to civilizations. One motivation for such comparative study is its heuristic value. Attempts…

Artificial Intelligence · Computer Science 2017-09-12 Dmitrii Yu. Manin , Yuri I. Manin

Encoding models are used for predicting brain activity in response to sensory stimuli with the objective of elucidating how sensory information is represented in the brain. Encoding models typically comprise a nonlinear transformation of…

Neurons and Cognition · Quantitative Biology 2017-03-13 Umut Güçlü , Marcel A. J. van Gerven

The brain is immensely complex, with diverse components and dynamic interactions building upon one another to orchestrate a wide range of functions and behaviors. Understanding patterns of these complex interactions and how they are…

Neurons and Cognition · Quantitative Biology 2024-08-06 Suman Kulkarni , Dani S. Bassett

Advancing our knowledge of how the brain processes information remains a key challenge in neuroscience. This thesis combines three different approaches to the study of the dynamics of neural networks and their encoding representations: a…

Neurons and Cognition · Quantitative Biology 2024-02-21 Guillermo B. Morales

Information processing in the brain is coordinated by the dynamic activity of neurons and neural populations at a range of spatiotemporal scales. These dynamics, captured in the form of electrophysiological recordings and neuroimaging, show…

Neurons and Cognition · Quantitative Biology 2025-10-27 Ramón Nartallo-Kaluarachchi , Morten L. Kringelbach , Gustavo Deco , Renaud Lambiotte , Alain Goriely

The exploration of brain-heart interactions within various paradigms, including affective computing, human-computer interfaces, and sensorimotor evaluation, stands as a significant milestone in biomarker development and neuroscientific…

Other Quantitative Biology · Quantitative Biology 2026-04-27 Diego Candia-Rivera , Luca Faes , Fabrizio De Vico Fallani , Mario Chavez

AI/ML models have rapidly gained prominence as innovations for solving previously unsolved problems and their unintended consequences from amplifying human biases. Advocates for responsible AI/ML have sought ways to draw on the richer…

Artificial Intelligence · Computer Science 2025-11-27 Peter S. Hovmand , Kari O'Donnell , Callie Ogland-Hand , Brian Biroscak , Douglas D. Gunzler

Recent advances in general-purpose AI systems with attention-based transformers offer a potential window into how the neocortex and cerebellum, despite their relatively uniform circuit architectures, give rise to diverse functions and,…

Neurons and Cognition · Quantitative Biology 2025-12-03 Shogo Ohmae , Keiko Ohmae