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We consider a reaction-diffusion equation on a network subjected to dynamic boundary conditions, with time delayed behaviour, also allowing for multiplicative Gaussian noise perturbations. Exploiting semigroup theory, we rewrite the…

Probability · Mathematics 2017-02-17 Francesco Cordoni , Luca Di Persio

Biochemical reaction networks are widely applied across scientific disciplines to model complex dynamic systems. We investigate the diffusion approximation of reaction networks with mass-action kinetics, focusing on the identifiability of…

Probability · Mathematics 2026-04-29 Louis Faul , Linard Hoessly , Panqiu Xia

Complex biochemical pathways or regulatory enzyme kinetics can be reduced to chains of elementary reactions, which can be described in terms of chemical kinetics. This discipline provides a set of tools for quantifying and understanding the…

Quantitative Methods · Quantitative Biology 2018-01-08 Elena Agliari , Adriano Barra , Giulio Landolfi , Sara Murciano , Sarah Perrone

The standard analysis of reaction networks based on deterministic rate equations fails in confined geometries, commonly encountered in fields such as astrochemistry, thin film growth and cell biology. In these systems the small reactant…

Other Condensed Matter · Physics 2007-05-23 Ofer Biham , Joachim Krug , Azi Lipshtat , Thomas Michely

In many situations, one can approximate the behavior of a quantum system, i.e. a wave function subject to a partial differential equation, by effective classical equations which are ordinary differential equations. A general method and…

Mathematical Physics · Physics 2007-05-23 Martin Bojowald , Aureliano Skirzewski

Systems of differential equations with polynomial right-hand sides are very common in applications. On the other hand, their mathematical analysis is very challenging in general, due to the possibility of complex dynamics: multiple basins…

Dynamical Systems · Mathematics 2022-05-31 Gheorghe Craciun , Jiaxin Jin , Polly Y. Yu

Chemical reaction networks with generalized mass-action kinetics lead to power-law dynamical systems. As a simple example, we consider the Lotka reactions and the resulting planar ODE. We characterize the parameters (positive coefficients…

Dynamical Systems · Mathematics 2022-09-14 Balázs Boros , Josef Hofbauer , Georg Regensburger , Stefan Müller

We solve a system of ordinary differential equations with an unknown functional form of a sink (reaction rate) term. We assume that the measurements (time series) of state variables are partially available, and we use recurrent neural…

Machine Learning · Computer Science 2017-10-09 Tobias Hagge , Panos Stinis , Enoch Yeung , Alexandre M. Tartakovsky

Some properties and relations satisfied by the polynomial solutions of the bispectral problem are studied. Given a differential operator, under certain restrictions its polynomial eigenfunctions are explicitly obtained, as well as the…

Spectral Theory · Mathematics 2021-11-30 D. Barrios Rolanía

Many dynamical systems arising in biology and other areas exhibit multistationarity (two or more positive steady states with the same conserved quantities). Although deciding multistationarity for a polynomial dynamical system is an…

Molecular Networks · Quantitative Biology 2019-02-08 Alicia Dickenstein , Mercedes Perez Millan , Anne Shiu , Xiaoxian Tang

Solving for detailed chemical kinetics remains one of the major bottlenecks for computational fluid dynamics simulations of reacting flows using a finite-rate-chemistry approach. This has motivated the use of fully connected artificial…

Computational Engineering, Finance, and Science · Computer Science 2021-10-11 Opeoluwa Owoyele , Pinaki Pal

Complex chemical reaction networks, which underlie many industrial and biological processes, often exhibit non-monotonic changes in chemical species concentrations, typically described using nonlinear models. Such non-monotonic dynamics are…

Adaptation and Self-Organizing Systems · Physics 2020-10-21 Zachary G. Nicolaou , Takashi Nishikawa , Schuyler B. Nicholson , Jason R. Green , Adilson E. Motter

A single dynamical system with time-delayed feedback can emulate networks. This property of delay systems made them extremely useful tools for Machine Learning applications. Here we describe several possible setups, which allow emulating…

Dynamical Systems · Mathematics 2021-06-30 Florian Stelzer , Serhiy Yanchuk

The spatially distributed reaction networks are indispensable for the understanding of many important phenomena concerning the development of organisms, coordinated cell behavior, and pattern formation. The purpose of this brief discussion…

Optimization and Control · Mathematics 2013-05-15 Marko Seslija , Jacquelien M. A. Scherpen , Arjan van der Schaft

The effective classical/quantum dynamics of a particle constrained on a closed line embedded in a higher dimensional configuration space is analyzed. By considering explicit examples it is shown how different reduction mechanisms produce…

High Energy Physics - Theory · Physics 2007-05-23 P. Maraner

We consider stochastically modeled chemical reaction systems with mass-action kinetics and prove that a product-form stationary distribution exists for each closed, irreducible subset of the state space if an analogous deterministically…

Probability · Mathematics 2010-01-31 David F. Anderson , Gheorghe Craciun , Thomas G. Kurtz

Dynamical networks are powerful tools for modeling a broad range of complex systems, including financial markets, brains, and ecosystems. They encode how the basic elements (nodes) of these systems interact altogether (via links) and evolve…

Physics and Society · Physics 2019-03-13 Edward Laurence , Nicolas Doyon , Louis J Dubé , Patrick Desrosiers

A kinetic equation for a dilute gas of hard spheres confined between two parallel plates separated a distance smaller than two particle dimeters is derived. It is a Boltzmann-like equation, which incorporates the effect of the confinement…

Statistical Mechanics · Physics 2016-11-23 J. Javier Brey , P. Maynar , M. I. García de Soria

Differential equations are used to model and predict the behaviour of complex systems in a wide range of fields, and the ability to solve them is an important asset for understanding and predicting the behaviour of these systems.…

Machine Learning · Computer Science 2023-01-31 Siddharth Nand , Yuecheng Cai

Chemical reaction networks (CRNs) are prototypical complex systems because reactions are nonlinear and connected in intricate ways, and they are also essential to understand living systems. Here, I discuss how recent developments in…

Statistical Mechanics · Physics 2020-12-23 Massimiliano Esposito