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Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Jun Wang , Yu Mao , Nan Guan , Chun Jason Xue

Multiple instance learning (MIL) has become a preferred method for gigapixel whole slide image (WSI) classification without requiring patch-level annotations. Current MIL research primarily relies on embedding-based approaches, which…

Computer Vision and Pattern Recognition · Computer Science 2025-03-10 Bryan Wong , Sungrae Hong , Mun Yong Yi

In recent years, the availability of digitized Whole Slide Images (WSIs) has enabled the use of deep learning-based computer vision techniques for automated disease diagnosis. However, WSIs present unique computational and algorithmic…

Image and Video Processing · Electrical Eng. & Systems 2021-06-15 Yash Sharma , Aman Shrivastava , Lubaina Ehsan , Christopher A. Moskaluk , Sana Syed , Donald E. Brown

In recent years, the integration of pre-trained foundational models with multiple instance learning (MIL) has improved diagnostic accuracy in computational pathology. However, existing MIL methods focus on optimizing feature extractors and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-24 Le Feng , Li Xiao

Whole slide imaging (WSI) refers to the digitization of a tissue specimen which enables pathologists to explore high-resolution images on a monitor rather than through a microscope. The formation of tissue folds occur during tissue…

Image and Video Processing · Electrical Eng. & Systems 2019-03-19 Morteza Babaie , H. R. Tizhoosh

Attention mechanism of late has been quite popular in the computer vision community. A lot of work has been done to improve the performance of the network, although almost always it results in increased computational complexity. In this…

Computer Vision and Pattern Recognition · Computer Science 2021-08-12 Abhinav Sagar

Even though convolutional neural networks (CNNs) are driving progress in medical image segmentation, standard models still have some drawbacks. First, the use of multi-scale approaches, i.e., encoder-decoder architectures, leads to a…

Computer Vision and Pattern Recognition · Computer Science 2020-02-18 Ashish Sinha , Jose Dolz

Whole Slide Image (WSI) classification is often formulated as a Multiple Instance Learning (MIL) problem. Recently, Vision-Language Models (VLMs) have demonstrated remarkable performance in WSI classification. However, existing methods…

Computer Vision and Pattern Recognition · Computer Science 2024-04-08 Hao Li , Ying Chen , Yifei Chen , Wenxian Yang , Bowen Ding , Yuchen Han , Liansheng Wang , Rongshan Yu

Whole slide imaging (WSI) has recently been cleared for primary diagnosis in the US. A critical challenge of WSI is to perform accurate focusing in high speed. Traditional systems create a focus map prior to scanning. For each focus point…

Computer Vision and Pattern Recognition · Computer Science 2019-04-26 Jun Liao , Yutong Jiang , Zichao Bian , Bahareh Mahrou , Aparna Nambiar , Alexander W. Magsam , Kaikai Guo , Yong Ku Cho , Guoan Zheng

Hyperspectral image (HSI) contains abundant spatial and spectral information, making it highly valuable for unmixing. In this paper, we propose a Dual-Stream Attention Network (DSANet) for HSI unmixing. The endmembers and abundance of a…

Image and Video Processing · Electrical Eng. & Systems 2024-06-05 Yufang Wang , Wenmin Wu , Lin Qi , Feng Gao

Medical image segmentation has made significant progress in recent years. Deep learning-based methods are recognized as data-hungry techniques, requiring large amounts of data with manual annotations. However, manual annotation is expensive…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Yi Lin , Yufan Chen , Kwang-Ting Cheng , Hao Chen

Semantic segmentation, a crucial task in computer vision, often relies on labor-intensive and costly annotated datasets for training. In response to this challenge, we introduce FuseNet, a dual-stream framework for self-supervised semantic…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Amirhossein Kazerouni , Sanaz Karimijafarbigloo , Reza Azad , Yury Velichko , Ulas Bagci , Dorit Merhof

This work explores a hybrid approach to segmentation as an alternative to a purely data-driven approach. We introduce an end-to-end U-Net based network called DU-Net, which uses additional frequency preserving features, namely the…

Image and Video Processing · Electrical Eng. & Systems 2020-04-16 Alakh Desai , Ruchi Chauhan , Jayanthi Sivaswamy

Medical imaging plays a critical role in various clinical applications. However, due to multiple considerations such as cost and risk, the acquisition of certain image modalities could be limited. To address this issue, many cross-modality…

Image and Video Processing · Electrical Eng. & Systems 2019-07-09 Dong Nie , Lei Xiang , Qian Wang , Dinggang Shen

This paper addresses the problem of liver cancer segmentation in Whole Slide Image (WSI). We propose a multi-scale image processing method based on automatic end-to-end deep neural network algorithm for segmentation of cancer area. A…

Image and Video Processing · Electrical Eng. & Systems 2020-07-29 Yanbo Feng , Adel Hafiane , Hélène Laurent

Whole-slide images (WSIs) are critical for cancer diagnosis due to their ultra-high resolution and rich semantic content. However, their massive size and the limited availability of fine-grained annotations pose substantial challenges for…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Daoxi Cao , Hangbei Cheng , Yijin Li , Ruolin Zhou , Xuehan Zhang , Xinyi Li , Binwei Li , Xuancheng Gu , Jianan Zhang , Xueyu Liu , Yongfei Wu

Histopathology image analysis is the golden standard of clinical diagnosis for Cancers. In doctors daily routine and computer-aided diagnosis, the Whole Slide Image (WSI) of histopathology tissue is used for analysis. Because of the…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Honglin Li , Yunlong Zhang , Chenglu Zhu , Jiatong Cai , Sunyi Zheng , Lin Yang

Segmentation of organs of interest in medical CT images is beneficial for diagnosis of diseases. Though recent methods based on Fully Convolutional Neural Networks (F-CNNs) have shown success in many segmentation tasks, fusing features from…

Artificial Intelligence · Computer Science 2024-05-10 Yanli Yuan , Bingbing Wang , Chuan Zhang , Jingyi Xu , Ximeng Liu , Liehuang Zhu

Minimally invasive surgery is a surgical intervention used to examine the organs inside the abdomen and has been widely used due to its effectiveness over open surgery. Due to the hardware improvements such as high definition cameras, this…

Image and Video Processing · Electrical Eng. & Systems 2021-08-04 Debesh Jha , Sharib Ali , Nikhil Kumar Tomar , Michael A. Riegler , Dag Johansen , Håvard D. Johansen , Pål Halvorsen

Tissue segmentation is a routine preprocessing step to reduce the computational cost of whole slide image (WSI) analysis by excluding background regions. Traditional image processing techniques are commonly used for tissue segmentation, but…

Image and Video Processing · Electrical Eng. & Systems 2024-01-25 Ruben T. Lucassen , Willeke A. M. Blokx , Mitko Veta