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Digital whole slide images (WSIs) are generally captured at microscopic resolution and encompass extensive spatial data. Directly feeding these images to deep learning models is computationally intractable due to memory constraints, while…

Image and Video Processing · Electrical Eng. & Systems 2024-11-22 Manahil Raza , Ruqayya Awan , Raja Muhammad Saad Bashir , Talha Qaiser , Nasir M. Rajpoot

Deep learning methods such as convolutional neural networks (CNNs) are difficult to directly utilize to analyze whole slide images (WSIs) due to the large image dimensions. We overcome this limitation by proposing a novel two-stage…

Image and Video Processing · Electrical Eng. & Systems 2021-06-15 Shivam Kalra , Mohammed Adnan , Sobhan Hemati , Taher Dehkharghanian , Shahryar Rahnamayan , Hamid Tizhoosh

We present a novel weakly-supervised framework for classifying whole slide images (WSIs). WSIs, due to their gigapixel resolution, are commonly processed by patch-wise classification with patch-level labels. However, patch-level labels…

Computer Vision and Pattern Recognition · Computer Science 2022-03-10 Tiange Xiang , Yang Song , Chaoyi Zhang , Dongnan Liu , Mei Chen , Fan Zhang , Heng Huang , Lauren O'Donnell , Weidong Cai

Whole slide imaging (WSI) is an emerging technology for digital pathology. The process of autofocusing is the main influence of the performance of WSI. Traditional autofocusing methods either are time-consuming due to repetitive mechanical…

Image and Video Processing · Electrical Eng. & Systems 2020-03-17 Qiang Li , Xianming Liu , Kaige Han , Cheng Guo , Xiangyang Ji , Xiaolin Wu

Segmenting an entire 3D image often has high computational complexity and requires large memory consumption; by contrast, performing volumetric segmentation in a slice-by-slice manner is efficient but does not fully leverage the 3D data. To…

Computer Vision and Pattern Recognition · Computer Science 2021-05-11 Rutu Gandhi , Yi Hong

Segmentation of biomedical images can assist radiologists to make a better diagnosis and take decisions faster by helping in the detection of abnormalities, such as tumors. Manual or semi-automated segmentation, however, can be a…

Image and Video Processing · Electrical Eng. & Systems 2021-02-11 Dhanunjaya Mitta , Soumick Chatterjee , Oliver Speck , Andreas Nürnberger

The expensive fine-grained annotation and data scarcity have become the primary obstacles for the widespread adoption of deep learning-based Whole Slide Images (WSI) classification algorithms in clinical practice. Unlike few-shot learning…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Kexue Fu , Xiaoyuan Luo , Linhao Qu , Shuo Wang , Ying Xiong , Ilias Maglogiannis , Longxiang Gao , Manning Wang

Digital pathology provides an excellent opportunity for applying fully convolutional networks (FCNs) to tasks, such as semantic segmentation of whole slide images (WSIs). However, standard FCNs face challenges with respect to…

Computer Vision and Pattern Recognition · Computer Science 2018-07-26 Feng Gu , Nikolay Burlutskiy , Mats Andersson , Lena Kajland Wilen

Medical image segmentation is vital to the area of medical imaging because it enables professionals to more accurately examine and understand the information offered by different imaging modalities. The technique of splitting a medical…

Image and Video Processing · Electrical Eng. & Systems 2024-09-01 Aitik Gupta , Joydip Dhar

Whole slide images (WSIs) pose unique challenges when training deep learning models. They are very large which makes it necessary to break each image down into smaller patches for analysis, image features have to be extracted at multiple…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Ozan Ciga , Tony Xu , Sharon Nofech-Mozes , Shawna Noy , Fang-I Lu , Anne L. Martel

Accurate medical image segmentation is critical for disease quantification and treatment evaluation. While traditional Unet architectures and their transformer-integrated variants excel in automated segmentation tasks. However, they lack…

Image and Video Processing · Electrical Eng. & Systems 2025-06-09 Guanqun Sun , Yizhi Pan , Weikun Kong , Zichang Xu , Jianhua Ma , Teeradaj Racharak , Le-Minh Nguyen , Junyi Xin

Deep learning techniques have successfully been employed in numerous computer vision tasks including image segmentation. The techniques have also been applied to medical image segmentation, one of the most critical tasks in computer-aided…

Computer Vision and Pattern Recognition · Computer Science 2020-06-30 Titinunt Kitrungrotsakul , Iwamoto Yutaro , Lanfen Lin , Ruofeng Tong , Jingsong Li , Yen-Wei Chen

In this work, we propose a new segmentation network by integrating DenseUNet and bidirectional LSTM together with attention mechanism, termed as DA-BDense-UNet. DenseUNet allows learning enough diverse features and enhancing the…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Wenming Cao , Philip L. H. Yu , Gilbert C. S. Lui , Keith W. H. Chiu , Ho-Ming Cheng , Yanwen Fang , Man-Fung Yuen , Wai-Kay Seto

We address the challenging problem of whole slide image (WSI) classification. WSIs have very high resolutions and usually lack localized annotations. WSI classification can be cast as a multiple instance learning (MIL) problem when only…

Computer Vision and Pattern Recognition · Computer Science 2021-04-05 Bin Li , Yin Li , Kevin W. Eliceiri

Bag-based Multiple Instance Learning (MIL) approaches have emerged as the mainstream methodology for Whole Slide Image (WSI) classification. However, most existing methods adopt a segmented training strategy, which first extracts features…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Jiangping Wen , Jinyu Wen , Meie Fang

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

Computer Vision and Pattern Recognition · Computer Science 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Accurate segmentation of medical images is crucial for diagnostic purposes, including cell segmentation, tumor identification, and organ localization. Traditional convolutional neural network (CNN)-based approaches struggled to achieve…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Daniya Najiha Abdul Kareem , Mustansar Fiaz , Noa Novershtern , Hisham Cholakkal

Medical image segmentation is a crucial task in the field of medical image analysis. Harmonizing the convolution and multi-head self-attention mechanism is a recent research focus in this field, with various combination methods proposed.…

Image and Video Processing · Electrical Eng. & Systems 2023-09-28 Lichao Wang , Jiahao Huang , Xiaodan Xing , Guang Yang

Recently there have been many algorithms proposed for the classification of very high resolution whole slide images (WSIs). These new algorithms are mostly focused on finding novel ways to combine the information from small local patches…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Long Nguyen , Aiden Nibali , Joshua Millward , Zhen He

In digital pathology, Whole Slide Image (WSI) analysis is usually formulated as a Multiple Instance Learning (MIL) problem. Although transformer-based architectures have been used for WSI classification, these methods require modifications…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Juan I. Pisula , Katarzyna Bozek
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