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Implicit Neural Representations (INRs) are a learning-based approach to accelerate Magnetic Resonance Imaging (MRI) acquisitions, particularly in scan-specific settings when only data from the under-sampled scan itself are available.…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Yamin Arefeen , Brett Levac , Zach Stoebner , Jonathan Tamir

Generative models have recently undergone significant advancement due to the diffusion models. The success of these models can be often attributed to their use of guidance techniques, such as classifier or classifier-free guidance, which…

Computer Vision and Pattern Recognition · Computer Science 2023-01-31 Gyeongnyeon Kim , Wooseok Jang , Gyuseong Lee , Susung Hong , Junyoung Seo , Seungryong Kim

How diffusion models generalize beyond their training set is not known, and is somewhat mysterious given two facts: the optimum of the denoising score matching (DSM) objective usually used to train diffusion models is the score function of…

Machine Learning · Computer Science 2025-04-18 John J. Vastola

Diffusion-weighted magnetic resonance imaging (DW-MRI) is used to characterize brain tissue microstructure employing tissue-specific biophysical models. A current limitation, however, is that most of the proposed models are based on the…

Purpose: Combining multi-site diffusion MRI (dMRI) data is hindered by inter-scanner variability, which confounds subsequent analysis. Previous harmonization methods require large, matched or traveling human subjects from multiple sites,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Hwihun Jeong , Qiang Liu , Kathryn E. Keenan , Elisabeth A. Wilde , Walter Schneider , Sudhir Pathak , Anthony Zuccolotto , Lauren J. O'Donnell , Lipeng Ning , Yogesh Rathi

Diffusion models have gained traction as powerful algorithms for synthesizing high-quality images. Central to these algorithms is the diffusion process, a set of equations which maps data to noise in a way that can significantly affect…

Machine Learning · Computer Science 2024-11-12 Subham Sekhar Sahoo , Aaron Gokaslan , Chris De Sa , Volodymyr Kuleshov

Models for inferring monocular shape of surfaces with diffuse reflection -- shape from shading -- ought to produce distributions of outputs, because there are fundamental mathematical ambiguities of both continuous (e.g., bas-relief) and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Xinran Nicole Han , Todd Zickler , Ko Nishino

Diffusion models have achieved state-of-the-art performance, demonstrating remarkable generalisation capabilities across diverse domains. However, the mechanisms underpinning these strong capabilities remain only partially understood. A…

Machine Learning · Computer Science 2025-10-03 Tyler Farghly , Peter Potaptchik , Samuel Howard , George Deligiannidis , Jakiw Pidstrigach

We investigate the approximation efficiency of score functions by deep neural networks in diffusion-based generative modeling. While existing approximation theories utilize the smoothness of score functions, they suffer from the curse of…

Machine Learning · Computer Science 2023-09-21 Song Mei , Yuchen Wu

While the manifold hypothesis is widely adopted in modern machine learning, complex data is often better modeled as stratified spaces -- unions of manifolds (strata) of varying dimensions. Stratified learning is challenging due to varying…

Machine Learning · Statistics 2026-04-14 Randy Martinez , Rong Tang , Lizhen Lin

Multi-echo Gradient Echo (mGRE) sequences provide valuable quantitative parametric maps, such as Quantitative Susceptibility Mapping (QSM) and transverse relaxation rate (R2*), sensitive to tissue iron and myelin. However, structural…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Sizhe Fang , Deqiang Qiu

Computational models of biophysical tissue properties have been widely used in diffusion MRI (dMRI) research to elucidate the link between microstructural properties and MR signal formation. For brain tissue, the research community has…

Medical Physics · Physics 2019-07-16 Santiago Coelho , Jose M. Pozo , Sune N. Jespersen , Alejandro F. Frangi

Diffusion models have shown incredible capabilities as generative models; indeed, they power the current state-of-the-art models on text-conditioned image generation such as Imagen and DALL-E 2. In this work we review, demystify, and unify…

Machine Learning · Computer Science 2022-08-26 Calvin Luo

The interactions between cells and the extracellular matrix are vital for the self-organisation of tissues. In this paper we present proof-of-concept to use machine learning tools to predict the role of this mechanobiology in the…

Tissues and Organs · Quantitative Biology 2023-04-03 Allison E. Andrews , Hugh Dickinson , James P. Hague

Diffusion models have achieved remarkable image generation quality surpassing previous generative models. However, a notable limitation of diffusion models, in comparison to GANs, is their difficulty in smoothly interpolating between two…

Computer Vision and Pattern Recognition · Computer Science 2023-12-13 Kaiwen Zhang , Yifan Zhou , Xudong Xu , Xingang Pan , Bo Dai

We propose a method called integrated diffusion for combining multimodal datasets, or data gathered via several different measurements on the same system, to create a joint data diffusion operator. As real world data suffers from both local…

Machine Learning · Computer Science 2022-03-07 Manik Kuchroo , Abhinav Godavarthi , Alexander Tong , Guy Wolf , Smita Krishnaswamy

Diffusion models, as a class of deep generative models, have recently emerged as powerful tools for robot skills by enabling stable training with reliable convergence. In this paper, we present an end-to-end framework for generating long,…

Stroke is a common disabling neurological condition that affects about one-quarter of the adult population over age 25; more than half of patients still have poor outcomes, such as permanent functional dependence or even death, after the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-19 Chia-Ling Tsai , Hui-Yun Su , Shen-Feng Sung , Wei-Yang Lin , Ying-Ying Su , Tzu-Hsien Yang , Man-Lin Mai

Recovering a 3D human mesh from a single RGB image is a challenging task due to depth ambiguity and self-occlusion, resulting in a high degree of uncertainty. Meanwhile, diffusion models have recently seen much success in generating…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Lin Geng Foo , Jia Gong , Hossein Rahmani , Jun Liu

Discrete diffusion models are increasingly competitive for language modeling, yet it remains unclear how their denoising objectives organize learning. Although these objectives target the full data distribution, we show that the exact…

Machine Learning · Computer Science 2026-05-15 Adrian Müller , Antoine Gonon , Zebang Shen , Ya-Ping Hsieh , Niao He