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Deep neural networks have brought remarkable breakthroughs in medical image analysis. However, due to their data-hungry nature, the modest dataset sizes in medical imaging projects might be hindering their full potential. Generating…

Deep generative modeling has emerged as a powerful tool for synthesizing realistic medical images, driving advances in medical image analysis, disease diagnosis, and treatment planning. This chapter explores various deep generative models…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Paul Friedrich , Yannik Frisch , Philippe C. Cattin

Generative models such as the variational autoencoder (VAE) and the generative adversarial networks (GAN) have proven to be incredibly powerful for the generation of synthetic data that preserves statistical properties and utility of…

Signal Processing · Electrical Eng. & Systems 2022-04-29 Moustafa Alzantot , Luis Garcia , Mani Srivastava

The advancement of generative AI, particularly in medical imaging, confronts the trilemma of ensuring high fidelity, diversity, and efficiency in synthetic data generation. While Generative Adversarial Networks (GANs) have shown promise…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Lorenzo Tronchin , Tommy Löfstedt , Paolo Soda , Valerio Guarrasi

Data limitation is one of the most common issues in training machine learning classifiers for medical applications. Due to ethical concerns and data privacy, the number of people that can be recruited to such experiments is generally…

Audio and Speech Processing · Electrical Eng. & Systems 2020-04-14 Bahman Mirheidari , Yilin Pan , Daniel Blackburn , Ronan O'Malley , Traci Walker , Annalena Venneri , Markus Reuber , Heidi Christensen

Every year thousands of patients are diagnosed with a glioma, a type of malignant brain tumor. Physicians use MR images as a key tool in the diagnosis and treatment of these patients. Neural networks show great potential to aid physicians…

Image and Video Processing · Electrical Eng. & Systems 2019-10-03 Eric Carver , Zhenzhen Dai , Evan Liang , James Snyder , Ning Wen

The generalizability of machine learning (ML) models for wearable monitoring in stroke rehabilitation is often constrained by the limited scale and heterogeneity of available data. Data augmentation addresses this challenge by adding…

Machine Learning · Computer Science 2024-11-01 Aaron J. Hadley , Christopher L. Pulliam

Medical image processing has been highlighted as an area where deep learning-based models have the greatest potential. However, in the medical field in particular, problems of data availability and privacy are hampering research progress…

Image and Video Processing · Electrical Eng. & Systems 2023-10-27 Christoph Angermann , Johannes Bereiter-Payr , Kerstin Stock , Markus Haltmeier , Gerald Degenhart

In the realm of dermatological diagnoses, where the analysis of dermatoscopic and microscopic skin lesion images is pivotal for the accurate and early detection of various medical conditions, the costs associated with creating diverse and…

Synthetic cardiac MRI (CMRI) generation has emerged as a promising strategy to overcome the scarcity of annotated medical imaging data. Recent advances in GANs, VAEs, diffusion probabilistic models, and flow-matching techniques aim to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Ishan Kumarasinghe , Dasuni Kawya , Madhura Edirisooriya , Isuri Devindi , Isuru Nawinne , Vajira Thambawita

The reconstruction of human visual inputs from brain activity, particularly through functional Magnetic Resonance Imaging (fMRI), holds promising avenues for unraveling the mechanisms of the human visual system. Despite the significant…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Yujian Xiong , Wenhui Zhu , Zhong-Lin Lu , Yalin Wang

Recent generative data augmentation methods conditioned on both image and text prompts struggle to balance between fidelity and diversity, as it is challenging to preserve essential image details while aligning with varied text prompts.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Tianchen Zhao , Xuanbai Chen , Zhihua Li , Jun Fang , Dongsheng An , Xiang Xu , Zhuowen Tu , Yifan Xing

Due to the lack of available annotated medical images, accurate computer-assisted diagnosis requires intensive Data Augmentation (DA) techniques, such as geometric/intensity transformations of original images; however, those transformed…

Computer Vision and Pattern Recognition · Computer Science 2019-04-01 Changhee Han , Leonardo Rundo , Ryosuke Araki , Yujiro Furukawa , Giancarlo Mauri , Hideki Nakayama , Hideaki Hayashi

Understanding the intensity characteristics of brain lesions is key for defining image-based biomarkers in neurological studies and for predicting disease burden and outcome. In this work, we present a novel foreground-based generative…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Berke Doga Basaran , Mengyun Qiao , Paul M. Matthews , Wenjia Bai

Variational autoencoder (VAE) is one of the most common techniques in the field of medical image generation, where this architecture has shown advanced researchers in recent years and has developed into various architectures. VAE has…

Machine Learning · Computer Science 2024-11-13 Khadija Rais , Mohamed Amroune , Abdelmadjid Benmachiche , Mohamed Yassine Haouam

Medical imaging datasets are inherently high dimensional with large variability and low sample sizes that limit the effectiveness of deep learning algorithms. Recently, generative adversarial networks (GANs) with the ability to synthesize…

Image and Video Processing · Electrical Eng. & Systems 2024-12-13 Apoorva Sikka , Skand Peri , Jitender Singh Virk , Usma Niyaz , Deepti R. Bathula

Neuroimaging consortia can enhance reliability and generalizability of findings by pooling data across studies to achieve larger sample sizes. To adjust for site and MRI protocol effects, imaging datasets are often harmonized based on…

Quantitative Methods · Quantitative Biology 2024-03-04 Shruti P. Gadewar , Alyssa H. Zhu , Iyad Ba Gari , Sunanda Somu , Sophia I. Thomopoulos , Paul M. Thompson , Talia M. Nir , Neda Jahanshad

Federated learning enables collaborative training of deep learning models across institutions without sharing sensitive patient data. However, its performance is often limited by small datasets and non-independent, identically distributed…

Image and Video Processing · Electrical Eng. & Systems 2026-04-17 Hongyi Pan , Ziliang Hong , Gorkem Durak , Ziyue Xu , Ulas Bagci

Multimode fiber~(MMF) imaging using deep learning has high potential to produce compact, minimally invasive endoscopic systems. Nevertheless, it relies on large, diverse real-world medical data, whose availability is limited by privacy…

Optics · Physics 2025-11-25 Jawaria Maqbool , M. Imran Cheema

In this paper, we address a key scientific problem in machine learning: Given a training set for an image classification task, can we train a generative model on this dataset to enhance the classification performance? (i.e., closed-set…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Haowen Wang , Guowei Zhang , Xiang Zhang , Zeyuan Chen , Haiyang Xu , Dou Hoon Kwark , Zhuowen Tu